dihexyl cadmium | 3431-71-8

• 分子结构分类: 有机化合物
• 英文名称: dihexyl cadmium
• 英文别名: dihexylcadmium
• CAS: 3431-71-8
• 化学式: C₁₂H₂₆Cd
• 分子量: 282.748
• InChiKey: LQIQGWOCWRMVHC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.07
• 重原子数：
  13.0
• 可旋转键数：
  10.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  dihexyl cadmium 、 2-萘甲酰氯 生成 1-[2]naphthyl-heptan-1-one
  参考文献：
  名称：

  369.物理性质和化学成分。第XLI部分。萘化合物

  摘要：

  DOI：

  10.1039/jr9650002072
• 作为产物：
  描述：

  溴己烷 、 cadmium(II) chloride 在 magnesium 作用下， 以 乙醚 为溶剂， 反应 2.5h， 生成 十二烷 、 dihexyl cadmium
  参考文献：
  名称：

  NMR-based molecular ruler for determining the depth of intercalants within the lipid bilayer

  摘要：

  The development of "molecular rulers" would allow one to quantitatively locate the penetration depth of intercalants within lipid bilayers. To this end, an attempt was made to correlate the C-13 NMR chemical shift of polarizable "reporter" carbons (e.g., carbonyls) of intercalants within DMPC liposomal bilayers - with the polarity it experiences, and with its Angstrom distance from the interface.This requires families of molecules with two "reporter carbons" separated by a known distance, residing at various depths/polarities within the bilayer. For this purpose, two homologous series of dicarbonyl compounds, methyl n-oxooctadecanoates and the corresponding n-oxooctadecanoic acids (n = 4-16), were synthesized. To assist in assignment and detection several homologs in each system were prepared (13)C(-)enriched in both carbonyls. Within each family, the number of carbons and functional groups remains the same, with the only difference being the location of the second ketone carbonyl along the fatty acid chain. Surprisingly, the head groups within each family are not anchored near the lipid-water interface, nor are they even all located at the same depth. Nevertheless, using an iterative best fit analysis of the data points enables one to obtain an exponential curve. The latter gives substantial insight into the correlation between polarity (measured in terms of the Reichardt polarity parameter, E-T(30)) and penetration depth into the liposomal bilayer. Still missing from this curve are data points in the moderate polarity range. (C) 2014 Elsevier Ireland Ltd. All rights reserved.

  DOI：

  10.1016/j.chemphyslip.2014.07.007
• 作为试剂：
  描述：

  环己甲酰氯 在 dihexyl cadmium 、 苯 作用下， 生成 1-cyclohexylheptan-1-one
  参考文献：
  名称：

  Decarboxylation of α-Substituted Glycidic Acids

  摘要：

  DOI：

  10.1021/ja01110a013

文献信息

• Structure and Reactivity. I. The Oximation Rates of Some Straight-Chain and Monomethyl-Substituted Alkanones
  作者：Paul G. Kletzke

  DOI：10.1021/jo01029a022

  日期：1964.6
• Acid-Catalyzed Condensation of Phenols and Keto Acids
  作者：ARTHUR J. YU、ALLAN R. DAY

  DOI：10.1021/jo01101a016

  日期：1958.7
• The Preparation and Some Reactions of 1,1,1-Trifluoro-2-alkenes¹
  作者：Kenneth N. Campbell、James O. Knobloch、Barbara K. Campbell

  DOI：10.1021/ja01166a014

  日期：1950.10
• Martin, Annales de Chimie (Cachan, France), 1959, vol. <13>1, p. 541,561
  作者：Martin

  DOI：——

  日期：——
• Synthesis, resolution, and antiplatelet activity of 3-substituted 1(3H)-isobenzofuranone
  作者：Hua Yang、Gao-Yun Hu、Jun Chen、Yi Wang、Zhong-Hua Wang

  DOI：10.1016/j.bmcl.2007.06.082

  日期：2007.9

  A series of 3-substituted-1(3H)-isobenzofuranone 6a-g and 7a-g were synthesized from phthalic anhydride. The compound 6a-g was resolved. The antiplatelet activities of these compounds were evaluated using in vitro experiment of platelet aggregation. The levels of antiplatelet activity were displayed as following sequence: l-isomer > dl-isomer > d-isomer, respectively. The alkylphthalide is more active than the corresponding alkenephthalide. All these compounds were less active than n-butylphthalide (NBP, 6c) and Aspirin (Asp). (c) 2007 Elsevier Ltd. All rights reserved.