N,N-dimethyl-2-(4-phenylthiazol-2-ylamino)acetamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N,N-dimethyl-2-(4-phenylthiazol-2-ylamino)acetamide
• 英文别名: N,N-dimethyl-2-[(4-phenyl-1,3-thiazol-2-yl)amino]acetamide
• 化学式: C₁₃H₁₅N₃OS
• 分子量: 261.348
• InChiKey: FKNUNHCXRQEIMC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  73.5
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-氨基安替比林 、 N,N-dimethyl-2-(4-phenylthiazol-2-ylamino)acetamide 在 盐酸 、 sodium nitrite 、 sodium acetate 作用下， 以 乙醇 为溶剂， 反应 2.0h， 以82%的产率得到2-(5-antipyrinylazo-4-phenylthiazol-2-ylamino)-N,N-dimethylacetamide
  参考文献：
  名称：

  Substituted 5-Antipyrinylazo-4-phenyl-2-aminothiazoles as Disperse Dyes for Dyeing Polyester Fabrics

  摘要：

  A series of some new substituted 5-antipyrinylazo4-phenyl-2-aminothiazole disperse dyes was synthesized by diazocoupling of 4-antipyrinyldiazonium chloride with aminothiazole derivatives. The synthesized dyes were characterized by UV-Vis absorption, IR, H-1 NMR, and MS spectroscopy. The dyes gave orange to reddish-violet shades with very good depth and levelness when applied to polyester fabrics as disperse dyes and their fastness properties were evaluated on polyester fibers. Also the position of color in CIELAB coordinates ( L*, a*, b*, H*, and C*) was assessed.

  DOI：

  10.1007/s00706-007-0749-4

文献信息

• Substituted 5-Antipyrinylazo-4-phenyl-2-aminothiazoles as Disperse Dyes for Dyeing Polyester Fabrics
  作者：Mohamed A. Metwally、Amira Metwally、Ebrahim Abdel-Galil、Fathy A. Amer

  DOI：10.1007/s00706-007-0749-4

  日期：2008.1

  A series of some new substituted 5-antipyrinylazo4-phenyl-2-aminothiazole disperse dyes was synthesized by diazocoupling of 4-antipyrinyldiazonium chloride with aminothiazole derivatives. The synthesized dyes were characterized by UV-Vis absorption, IR, H-1 NMR, and MS spectroscopy. The dyes gave orange to reddish-violet shades with very good depth and levelness when applied to polyester fabrics as disperse dyes and their fastness properties were evaluated on polyester fibers. Also the position of color in CIELAB coordinates ( L*, a*, b*, H*, and C*) was assessed.