9,10-dioxo-9,10-dihydroanthracene-2,7-disulfonyl dichloride | 36003-56-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 9,10-dioxo-9,10-dihydroanthracene-2,7-disulfonyl dichloride
• 英文别名: anthraquinone-2,7-disulfonylchloride；9,10-dioxo-9,10-dihydro-anthracene-2,7-disulfonyl chloride；Anthrachinon-disulfonsaeure-(2.7)-dichlorid；9,10-Dioxo-9,10-dihydro-anthracen-2,7-disulfonylchlorid；9,10-dioxo-9,10-dihydro-2,7-anthracenedisulfonyl dichloride；9,10-Dioxo-9,10-dihydro-anthracene-2,7-disulfonyl dichloride；9,10-dioxoanthracene-2,7-disulfonyl chloride
• CAS: 36003-56-2
• 化学式: C₁₄H₆Cl₂O₆S₂
• 分子量: 405.236
• InChiKey: FDAGIURIANMEOD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  24
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  119
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  9,10-dioxo-9,10-dihydroanthracene-2,7-disulfonyl dichloride 在 氯化亚砜 作用下， 生成 2,7-二氯蒽醌
  参考文献：
  名称：

  DE284976

  摘要：

  公开号：
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 氯磺酸 作用下， 生成 9,10-dioxo-9,10-dihydroanthracene-2,7-disulfonyl dichloride
  参考文献：
  名称：

  DE266521

  摘要：

  公开号：

文献信息

• [EN] TRICYCLIC COMPOUNDS<br/>[FR] COMPOSÉS TRICYCLIQUES
  申请人：VIVACE THERAPEUTICS INC

  公开号：WO2017058716A1

  公开（公告）日：2017-04-06

  Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for treating cancers or congenital diseases. Specific cancers and congenital disease includes those that are mediated by YAP/TAZ.

  本文提供了包含所述化合物的药物组合物，用于治疗癌症或先天性疾病。具体的癌症和先天性疾病包括那些由YAP/TAZ介导的疾病。
• FLUORENES AND ANTHRACENES THAT INHIBIT P2X3 AND P2X2/3 CONTAINING RECEPTORS
  申请人：——

  公开号：US20040019042A1

  公开（公告）日：2004-01-29

  Compounds of formula (I) 1 are novel P2X 3 and P2X 2 /P2X 3 containing receptor antagonists and are useful in treating pain, urinary incontinence, and bladder overactivity.

  式(I)1的化合物是新型的含有P2X3和P2X2/P2X3受体拮抗剂，可用于治疗疼痛、尿失禁和膀胱过度活动。
• [EN] DERIVATIVES OF MULTI-RING AROMATIC COMPOUNDS AND USES AS ANTI-TUMOR AGENTS<br/>[FR] DÉRIVÉS DE COMPOSÉS AROMATIQUES À NOYAUX MULTIPLES ET UTILISATIONS COMME AGENTS ANTI-TUMORAUX
  申请人：AVALON PHARMACEUTICALS

  公开号：WO2010082912A1

  公开（公告）日：2010-07-22

  Chemical agents, such as disulfonamide derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine, and similar heterocyclic ring structures, including salts thereof, that act as anti-cancer and anti-tumor agents, are disclosed, along with methods for preparing such agents, as well as pharmaceutical compositions containing such agents as active ingredients and methods of using these as therapeutic agents.

  本文披露了化学试剂，如萘、蒽、联苯并呋喃、二苯并吡喃和吖啶的二磺酰胺衍生物等，以及类似的杂环环结构，包括其盐，作为抗癌和抗肿瘤试剂，并披露了制备这些试剂的方法，以及含有这些试剂作为活性成分的药物组合物，以及使用这些试剂作为治疗试剂的方法。
• DIMERIC IAP INHIBITORS
  申请人：STRAUB Christopher Sean

  公开号：US20110206690A1

  公开（公告）日：2011-08-25

  The present invention provides compounds of formula M-L-M′ (where M and M′ are each independently a monomeric moiety of Formula (I) and L is a linker). The dimeric compounds have been found to be effective in promoting apoptosis in rapidly dividing cells.

  本发明提供了公式M-L-M′的化合物（其中M和M′分别是公式（I）中的单体基团，L是连接物）。已发现二聚化合物在促进快速分裂细胞凋亡方面具有有效性。
• [EN] ANTHRAQUINONE DIOXIMES AND USES THEREOF<br/>[FR] DIOXIMES D'ANTHRAQUINONE ET LEURS UTILISATIONS
  申请人：AVALON PHARMACEUTICALS

  公开号：WO2010059142A1

  公开（公告）日：2010-05-27

  Anthraquinone dioximes and their derivatives are disclosed for use in treatment of diseases, especially cancer, such as colon and colorectal cancer. Methods of preparing such derivatives are also presented. Compositions of these compounds, as well as metabolites of said compounds and their use in gene modulation are also described.

  Anthraquinone dioximes 及其衍生物被揭示用于治疗疾病，特别是癌症，如结肠和结直肠癌。还介绍了制备这些衍生物的方法。同时，还描述了这些化合物的组成，以及其代谢物和在基因调控中的使用。