N-(2-hydroxyethyl)perfluoro-2-methyl-3-oxahexanamide | 904055-94-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-(2-hydroxyethyl)perfluoro-2-methyl-3-oxahexanamide
• 英文别名: N-(perfluoro-2-methyl-3-oxahexanoyl)-2-aminoethanol；2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)-N-(2-hydroxyethyl)propanamide
• CAS: 904055-94-3
• 化学式: C₈H₆F₁₁NO₃
• 分子量: 373.123
• InChiKey: OMNDMPVDPPWECC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  23
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  58.6
• 氢给体数：
  2
• 氢受体数：
  14

反应信息

• 作为反应物：
  描述：

  柠康酸酐 、 N-(2-hydroxyethyl)perfluoro-2-methyl-3-oxahexanamide 在 对甲苯磺酸 作用下， 以 甲苯 为溶剂， 反应 40.0h， 生成
  参考文献：
  名称：

  FLUORINATED ESTERS

  摘要：

  一种化合物，包括Formula 2A，2B或2C(Ra—O—CO—)2Y，其中： Formula 2A：Ra—O—CO—Y—CO—O—(CH2CH2)Rf Formula 2B：Ra—O—CO—Y—CO—O—R Formula 2C 其中： Ra是基团(i) Rf(CH2CF2)d—(CgH2g)—；(ii) RfOCF2CF2—(CgH2g)—；(iii) RfOCFHCF2O(CH2CH2O)v—(CgH2g)—；(iv) RfOCFHCF2O(CwH2w)—；(v) RfOCF(CF3)CONH—(CgH2g)—；或(vi) Rf(CH2)h[(CF2CF2)i(CH2CH2)j]k；每个Rf独立地为CcF(2c+1)；c为2至约6；d为1至约3；g为1至4；v为1至约4；w为约3至约12；h为1至约6；i、j和k每个独立地为1、2或3，或它们的混合；但vi中的碳原子总数约为8至约22；Y是具有烯烃不饱和度的线性或支链二元基，其化学式为—CeH(2e−2)—，其中e为2或3；R为H或线性或支链烷基CbH(2b+1)—；b为1至约18。

  公开号：

  US20100004482A1
• 作为产物：
  描述：

  全氟(2-甲基-3-氧杂己基)氟化物 、 C.I.酸性橙108 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 反应 15.0h， 以82%的产率得到N-(2-hydroxyethyl)perfluoro-2-methyl-3-oxahexanamide
  参考文献：
  名称：

  新型全氟烷基醚衍生物的合成

  摘要：

  基于市售的全氟烷基醚酰基氟，已经设计和制备了一系列新型的含氟醚单体。用烯丙醇，甲基丙烯酸2-羟乙酯或N-烯丙基甲胺处理酰基氟，可以直接形成相应的含乙烯基的氟化单体。酰氯与缩水甘油可制得高产率的氟化环氧单体。同时，由二乙醇胺或3-氨基-1，2-丙二醇制得氟化二醇。此外，还获得了氟化单胺，氟化一元醇和氟化二氯化物。这些氟化单体中的大多数在室温下为液体，并在普通有机溶剂中表现出良好的溶解性。

  DOI：

  10.1007/s11164-018-3411-3

文献信息

• FLUORINATED ALCOHOLS
  申请人：Mclain Stephan James

  公开号：US20100004478A1

  公开（公告）日：2010-01-07

  A compound comprising Formula 5 R f OCFHCF 2 O(CH 2 CH 2 O) v —H  Formula 5 wherein R f is C c F (2c+1) ; c is 2 to about 6; and v is 2 to about 4; and a process for its preparation comprising contacting a compound of Formula 6 R f —O—CF═CF 2 Formula 6 wherein R f is C c F (2c+1) , and c is 2 to about 6, with a compound of Formula 7 HO—(CH 2 CH 2 O) v —H  Formula 7 wherein v is 2 to about 4.

  一种化合物，其化学式为5RfOCFHCF2O(CH2CH2O)v—H，其中Rf为CcF(2c+1)；c为2至约6；v为2至约4；以及一种制备该化合物的方法，包括将化合物6的化合物与化合物7接触，化合物6的化学式为Rf—O—CF═CF2，其中Rf为CcF(2c+1)，c为2至约6，化合物7的化学式为HO—(CH2CH2O)v—H，其中v为2至约4。
• POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE
  申请人：Qiu Weiming

  公开号：US20100233419A1

  公开（公告）日：2010-09-16

  A composition comprising a copolymer having repeating units in any sequence of Formula I wherein R f is a straight or branched perfluoroalkyl group having from about 1 to about 20 carbon atoms, or a mixture thereof, which is optionally interrupted by at least one oxygen atom, X 3 is oxygen or X 1 , each X 1 is independently an organic divalent linking group having from about 1 to about 20 carbon atoms, optionally containing an oxygen, nitrogen, or sulfur, or a combination thereof, G is F or CF 3 , A is an amide, j is zero or positive integer, X 2 is an organic linking group, Y is O, N or S, h is zero when Y is N, and h is one when Y is O or S, Z is H, a straight or branched alkyl group having from about 1 to about 4 carbon atoms, or halide, B is H or wherein R f , X 1 , X 3 , G, A, and j are as defined above, provided that when B is H, j is a positive integer, m is a positive integer, q is zero or a positive integer when Y is O, and q is a positive integer when Y is N or S, p is zero or a positive integer when Y is O, and p is a positive integer when Y is N or S, each W is independently various copolymer units.

  一种包含具有任何顺序的重复单元的共聚物的组合物，其化学式为I，其中Rf是直链或支链的全氟烷基基团，具有约1到约20个碳原子，或二者的混合物，可由至少一个氧原子中断，X3是氧或X1，每个X1独立地是具有约1到约20个碳原子的有机二价连接基团，可包含氧、氮或硫，或二者的组合，G是F或CF3，A是酰胺，j是零或正整数，X2是有机连接基团，Y是O、N或S，当Y是N时，h为零，当Y是O或S时，h为一，Z是H，直链或支链的具有约1到约4个碳原子的烷基基团，或卤素，B是H或，其中Rf、X1、X3、G、A和j如上所定义，但当B为H时，j为正整数，m为正整数，当Y为O时，q为零或正整数，当Y为N或S时，q为正整数，当Y为O时，p为零或正整数，当Y为N或S时，p为正整数，每个W独立地是各种共聚物单元。
• PARTIALLY FLUORINATED SULFONATED SURFACTANTS
  申请人：Murphy Peter Michael

  公开号：US20100003737A1

  公开（公告）日：2010-01-07

  The present invention comprises a compound comprising Formula 1A, 1B, or 1C (R a —O—CO—) 2 X  Formula 1A R a —O—CO—X—CO—O—(CH 2 CH 2 )R f Formula 1B R a —O—CO—X—CO—O—R  Formula 1C wherein R a is the group R f (CH 2 CF 2 ) d —(C g H 2g )—; R f OCF 2 CF 2 —(C g H 2g )—; R f OCFHCF 2 O(CH 2 CH 2 O) v —(C g H 2g )—; R f OCFHCF 2 O(C w H 2w ); R f OCF(CF 3 )CONH—(C g H 2g ); or R f (CH 2 ) h [(CF 2 CF 2 ) i (CH 2 CH 2 ) j ] k ; R f is C c F (2c+1) ; d is 1 to about 3; g is 1 to 4; v is 1 to about 4; w is from about 3 to about 12; h is 1 to about 6; i, j, and k are each independently 1, 2, or 3, or a mixture thereof; provided that the total number of carbon atoms in group (vi) is from about 8 to about 22; X is a linear or branched difunctional alkyl sulfonate group —C e H (2e−1) (SO 3 M)-, wherein e is 2 or 3; M is a monovalent cation selected from the group consisting of hydrogen, ammonium, alkali metal, or alkaline earth metal; R is H or a linear or branched alkyl group C b H (2b+1) —; and b is from 1 to about 18.

  本发明包括一种化合物，其包括公式1A、1B或1C(Ra—O—CO—)2X，其中：公式1A为Ra—O—CO—X—CO—O—( )Rf；公式1B为Ra—O—CO—X—CO—O—R；公式1C为Ra—O—CO—X—CO—O—(vi)，其中：R为Rf(CH2CF2)d—(CgH2g)—、RfOCF2CF2—(CgH2g)—、RfOCFHCF2O( O)v—(CgH2g)—、RfOCFHCF2O(CwH2w)、RfOCF(CF3)CONH—(CgH2g)或Rf( )h[(CF2CF2)i( )j]k；Rf为CcF(2c+1)；d为1至约3；g为1至4；v为1至约4；w为约3至约12；h为1至约6；i、j和k各自独立地为1、2或3，或其混合物；所述(vi)中的碳原子总数为约8至约22；X为线性或支链双官能团烷基磺酸盐基——CeH(2e−1)(SO3M)-，其中e为2或3；M为从氢、铵、碱金属或碱土金属中选择的一价阳离子；R为H或线性或支链烷基CbH(2b+1)—；b为1至约18。
• FLUORINATED POLYOXYALKYLENE GLYCOL DIESTER SURFACTANTS
  申请人：Murphy Peter Michael

  公开号：US20100099837A1

  公开（公告）日：2010-04-22

  A fluorinated polyoxyalkylene glycol diester surfactant of formula 1 B—X—COCH 2 O—[—C p H 2p O—] n —CH 2 CO—X—R a (1) wherein B is M or R a , M is an ionizable hydrogen, ammonium, alkali metal, or alkaline earth metal, p is from about 2 to about 4, n is from about 5 to about 43, X is O, S, or SCH 2 CH 2 O, R a is R f (CH 2 CF 2 ) d —(C g H 2g )—; R f [OCF 2 CF 2 ] r (C g H 2g )—; R f (CH 2 ) h [(CF 2 CF 2 ) i (CH 2 CH 2 ) j ] k —; or R f OY—; Y is CFHCF 2 O(CH 2 CH 2 O) v —(C g H 2g )—; CFHCF 2 O(C w H 2w )—; or CF(CF 3 )CONH—(C g H 2g )—; each R f is independently C c F (2c+1) wherein c is 1 to about 6; d is 1 to about 3; g is 1 to about 4; s is 0 or 1; r is 1 to about 4; h is 1 to about 6; i, j, and k are each independently 1, 2, or 3, or a mixture thereof; provided that the total number of carbon atoms in R f (CH 2 ) h [(CF 2 CF 2 ) i (CH 2 CH 2 ) j ] k —is from about 8 to about 22; v is 1 to about 4; and w is from about 2 to about 12.

  化学式1B-X-CO O-[CpH2pO]n- CO-X-Ra的氟代聚氧化烷基二酯表面活性剂（1） 其中，B为M或Ra，M为可离子化氢、铵、碱金属或碱土金属，p为大约2至4，n为大约5至43，X为O、S或S O，Ra为Rf(CH2CF2)d-(CgH2g)-、Rf[OCF2CF2]r(CgH2g)-、Rf( )h[(CF2CF2)i( )j]k-或RfOY-，Y为CFHCF2O( O)v-(CgH2g)-、CFHCF2O(CwH2w)-或CF(CF3)CONH-(CgH2g)-，每个Rf独立地为CcF(2c+1)，其中c为1至6，d为1至3，g为1至4，s为0或1，r为1至4，h为1至6，i、j和k分别为1、2或3或其混合物，但Rf( )h[(CF2CF2)i( )j]k-中的碳原子总数约为8至22，v为1至4，w为大约2至12。
• Fluorinated polyoxyalkylene glycol diester surfactants
  申请人：E.I. duPont de Nemours and Company

  公开号：US08022107B2

  公开（公告）日：2011-09-20

  A fluorinated polyoxyalkylene glycol diester surfactant of formula 1 B—X—COCH2O—[—CpH2pO—]n—CH2CO—X—Ra  (1) wherein B is M or Ra, M is an ionizable hydrogen, ammonium, alkali metal, or alkaline earth metal, p is from about 2 to about 4, n is from about 5 to about 43, X is O, S, or SCH2CH2O, Ra is Rf(CH2CF2)d—(CgH2g)—; Rf[OCF2CF2]r(CgH2g)—; Rf(CH2)h[(CF2CF2)i(CH2CH2)j]k-; or RfOY—; Y is CFHCF2O(CH2CH2O)v-(CgH2g)—; CFHCF2O(CwH2w)—; or CF(CF3)CONH—(CgH2g)—; each Rf is independently CcF(2c+1) wherein c is 1 to about 6; d is 1 to about 3; g is 1 to about 4; or 1; r is 1 to about 4; h is 1 to about 6; i, j, and k are each independently 1, 2, or 3, or a mixture thereof; provided that the total number of carbon atoms in Rf(CH2)h[(CF2CF2)i(CH2CH2)j]k— is from about 8 to about 22; v is 1 to about 4; and w is from about 2 to about 12.

  一种化学物质的化学式为1B—X—CO O—[—CpH2pO—]n— CO—X—Ra 的氟代聚氧烷基二酯表面活性剂，其中B是M或Ra，M是可电离的氢、铵、碱金属或碱土金属，p为约2至4，n为约5至43，X为O、S或S O，Ra是Rf(CH2CF2)d—(CgH2g)—；Rf[OCF2CF2]r(CgH2g)—；Rf( )h[(CF2CF2)i( )j]k-；或RfOY—；Y为CFHCF2O( O)v-(CgH2g)—；CFHCF2O(CwH2w)—；或CF(CF3)CONH—(CgH2g)—；每个Rf独立地为CcF(2c+1)，其中c为1至约6，d为1至约3，g为1至约4或1，r为1至约4，h为1至约6，i、j和k分别为1、2或3，或其混合物；提供Rf( )h[(CF2CF2)i( )j]k—中碳原子的总数约为8至22；v为1至约4，w为约2至12。