OZONOLYSIS REACTIONS IN LIQUID CO2 AND CO2-EXPANDED SOLVENTS
申请人:University Of Kansas
公开号:EP2209547A2
公开(公告)日:2010-07-28
Ozonolysis Reactions in Liquid CO2 and CO2-Expanded Solvents
申请人:UNIVERSITY OF KANSAS
公开号:US20130240781A1
公开(公告)日:2013-09-19
A method for increasing ozone concentration in a liquid can include: providing a gas having ozone; introducing the ozone-containing gas into a liquid, wherein the liquid and ozone combination has a temperature between about 0.8 and about 1.5 times the critical temperature of ozone; and increasing isothermally, the pressure of the ozone-containing gas above the liquid to about 0.3 to about 5 times the critical pressure of ozone so as to increase the ozone concentration in the liquid. The temperature is expressed in absolute units (Kelvin or Rankin). The method can be used for removing ozone from a gas or for purifying ozone. The liquid having a high ozone concentration can be used for ozonolysis of a substrate.
COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS
申请人:ModernaTX, Inc.
公开号:US20180028664A1
公开(公告)日:2018-02-01
This disclosure provides improved lipid-based compositions, including lipid nanoparticle compositions, and methods of use thereof for delivering agents in vivo including nucleic acids and proteins. These compositions are not subject to accelerated blood clearance and they have an improved toxicity profile in vivo.