hibiscus acid | 27750-11-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: hibiscus acid
• 英文别名: ALLO-2-hydroxycitric acid；(1S,2R)-1,2-dihydroxypropane-1,2,3-tricarboxylic acid
• CAS: 27750-11-4
• 化学式: C₆H₈O₈
• 分子量: 208.125
• InChiKey: ZMJBYMUCKBYSCP-AWFVSMACSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.6
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  152
• 氢给体数：
  5
• 氢受体数：
  8

安全信息

• 海关编码：
  2918199090

反应信息

• 作为反应物：
  描述：

  hibiscus acid 在 calcium hydroxide 作用下， 以 水 为溶剂， 生成 calcium (-)-hydroxycitric acid
  参考文献：
  名称：

  WO2006/81682

  摘要：

  公开号：
• 作为产物：
  描述：

  calcium (-)-hydroxycitric acid 生成 hibiscus acid
  参考文献：
  名称：

  WO2006/81682

  摘要：

  公开号：

文献信息

• COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS
  申请人：Chodorowski-Kimmes Sandrine

  公开号：US20100239509A1

  公开（公告）日：2010-09-23

  The present patent application relates to a cosmetic or dermatological composition comprising, in a cosmetically or dermatologically acceptable medium, a polymer comprising: (a) a polymer backbone that may be obtained by reaction: of a polyol comprising 3 to 6 hydroxyl groups; of a monocarboxylic acid containing 6 to 32 carbon atoms; of a polycarboxylic acid comprising at least two carboxylic groups COOH, and/or of a cyclic anhydride such as a polycarboxylic acid and/or of a lactone comprising at least one carboxylic group COOH; and (b) at least one junction group linked to the said polymer backbone and capable of establishing H bonds with one or more partner junction groups, each pairing of a junction group involving at least three H (hydrogen) bonds. The patent application also concerns a cosmetic treatment process using the said composition.

  本专利申请涉及一种化妆品或皮肤科学组合物，包括在化妆品或皮肤科学上可接受的介质中，包含以下聚合物的组合物：(a) 由以下反应得到的聚合物骨架：含有3至6个羟基的多元醇；含有6至32个碳原子的一元羧酸；至少含有两个羧基COOH的多元羧酸，和/或类似多元羧酸的环酐和/或至少含有一个羧基COOH的内酯；以及(b) 至少一个连接到所述聚合物骨架的连接基团，并能够与一个或多个配对连接基团建立H键，每个连接基团的配对涉及至少三个H（氢）键。该专利申请还涉及使用所述组合物的化妆品处理过程。
• COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION
  申请人：GIUSTINIANI Pascal

  公开号：US20090028807A1

  公开（公告）日：2009-01-29

  The present application relates to a cosmetic or pharmaceutical, in particular lipstick, composition comprising a polycondensate The application also relates to a method of cosmetic treatment using the composition, the polycondensate thus defined and a method of preparing the polycondensate.

  本申请涉及一种化妆品或药用品，特别是口红，包括聚缩酸酯的组合物。该申请还涉及一种使用该组合物进行化妆处理的方法，所述聚缩酸酯的定义以及一种制备聚缩酸酯的方法。
• COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT
  申请人：Malle Gerard

  公开号：US20100272660A1

  公开（公告）日：2010-10-28

  The present application relates to a cosmetic or pharmaceutical composition comprising a polycondensate capable of being obtained by the reaction of the following monomers alone: of 10 to 30% by weight, relative to the total weight of the polycondensate, of one or more polyols comprising 3 to 6 hydroxyl groups; of 30 to 80% by weight, relative to the total weight of the polycondensate, of one or more linear, branched and/or cyclic, saturated or unsaturated, non-aromatic monocarboxylic acids comprising 6 to 32 carbon atoms; of 1 to 40% by weight, relative to the total weight of the polycondensate, of one or more polycarboxylic acids and/or cyclic anhydrides of such a polycarboxylic acid and/or lactones comprising at least one COOH group; and optionally of 0.1 to 15% by weight, relative to the total weight of the polycondensate, of one or more silicones having a hydroxyl and/or carboxyl functional group. The application also relates to a method of cosmetic treatment using the said composition, and the polycondensate thus defined.

  本申请涉及一种化妆品或药用组合物，包括由以下单体反应而得的聚缩酸酯：相对于聚缩酸酯的总重量，占10至30%的一种或多种含有3至6个羟基的多元醇；占30至80%的一种或多种线性、支链和/或环状、饱和或不饱和、非芳香族的单羧酸，含有6至32个碳原子；占聚缩酸酯总重量的1至40%的一种或多种多羧酸和/或多羧酸的环状酐和/或含有至少一个COOH基团的内酯；以及可选地占聚缩酸酯总重量的0.1至15%的一种或多种硅氧烷，具有羟基和/或羧基官能团。该申请还涉及使用所述组合物进行化妆处理的方法，以及如此定义的聚缩酸酯。
• ORGANIC ACIDS AS AGENTS TO DISSOLVE CALCIUM MINERALS IN PATHOLOGICAL CALCIFICATION AND USES THEREOF
  申请人：Rimer Jeffrey D.

  公开号：US20150297545A1

  公开（公告）日：2015-10-22

  In an embodiment of the present disclosure, there is provided a composition for dissolving calcium oxalate crystals thereby inhibiting/preventing further growth of crystals. In some embodiments, such a composition comprises at least one stereoisomer of hydroxycitrate, a derivative of the organic acid citrate. Such a method comprises administering to the subject an effective amount of the aforementioned composition. In another embodiment, the present disclosure pertains to a method of treating kidney stone disorder. Such a method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. In yet another embodiment, the present disclosure relates to a method of treating calcium oxalate stone disease. In an embodiment, the method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition.

  在本公开的实施例中，提供了一种用于溶解草酸钙晶体从而抑制/预防晶体进一步生长的组合物。在一些实施例中，这样的组合物包括至少一种羟基柠檬酸的立体异构体，这是有机酸柠檬酸的衍生物。这种方法包括向受试者施用上述组合物的有效量。在另一实施例中，本公开涉及一种治疗肾结石疾病的方法。这种方法包括向需要的受试者施用上述组合物的治疗有效量。在另一实施例中，本公开涉及一种治疗草酸钙结石疾病的方法。在一实施例中，该方法包括向需要的受试者施用上述组合物的治疗有效量。
• Novel acyclic chiral derivatives of hibiscus acid and the process of preparing the same
  申请人：——

  公开号：US20020045769A1

  公开（公告）日：2002-04-18

  The present invention relates to a novel acyclic chiral derivatives of Hibiscus acid of formula I, 1 wherein: R 1 ═R 5 ═lower aryl or alkyl ester or substituted aryl or alkyl alcohol R 3 ═substituted aryl or alkyl ester or substituted aryl alcohol R 2 ═R4═hydroxyl or 2 and a process for preparing the same.

  本发明涉及一种新型无环手性Hibiscus酸衍生物，其化学式为I,1，其中：R1═R5═低芳基或烷基酯或取代芳基或烷基醇；R3═取代芳基或烷基酯或取代芳基醇；R2═R4═羟基或2，以及其制备方法。