D-α-methylleucine amide | 113565-54-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: D-α-methylleucine amide
• 英文别名: (2R)-2-amino-2,4-dimethylpentanamide
• CAS: 113565-54-1
• 化学式: C₇H₁₆N₂O
• 分子量: 144.217
• InChiKey: FTJJDCJLMLWWPS-SSDOTTSWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  69.1
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  D-α-methylleucine amide 在 盐酸 作用下， 反应 72.0h， 以97.3%的产率得到2-甲基亮氨酸
  参考文献：
  名称：

  Synthesis of optically pure .alpha.-alkylated .alpha.-amino acids and a single-step method for enantiomeric excess determination

  摘要：

  DOI：

  10.1021/jo00243a049
• 作为产物：
  描述：

  α-methylleucine amide 生成 D-α-methylleucine amide
  参考文献：
  名称：

  Synthesis of optically pure .alpha.-alkylated .alpha.-amino acids and a single-step method for enantiomeric excess determination

  摘要：

  DOI：

  10.1021/jo00243a049

文献信息

• PROCESS FOR THE PREPARATION OF (1R,3R)- AND (1S,3S)-2,2-DIHALO-3-(SUBSTITUTED PHENYL)CYCLOPROPANECARBOXYLIC ACIDS
  申请人：Dow AgroSciences LLC

  公开号：US20180099919A1

  公开（公告）日：2018-04-12

  The (1R,3R)- or (1S,3S)-enantiomer of 2,2-dichloro-3-(substituted phenyl)cyclopropane-carboxylic acid is prepared in a process involving chemical resolution of a racemic mixture of a trans-2,2-dichloro-3-(substituted phenyl)cyclopropanecarboxylic acid with an enantiomeric amine, isolation of a diastereomeric amine salt and finally treatment of the salt with an acid.

  2,2-二氯-3-(取代苯基)环丙烷羧酸的(1R,3R)-或(1S,3S)-对映体是通过化学拆分反式的2,2-二氯-3-(取代苯基)环丙烷羧酸的外消旋混合物与对映异构胺的化学拆分、分离出的对映异构胺盐和最终用酸处理盐的过程制备的。
• Process for the preparation of (1R,3R)- and (1S,3S)-2,2-dihalo-3-(substituted phenyl)cyclopropanecarboxylic acids
  申请人：Dow AgroSciences LLC

  公开号：US10239817B2

  公开（公告）日：2019-03-26

  The (1R,3R)- or (1S,3S)-enantiomer of 2,2-dichloro-3-(substituted phenyl)cyclopropane-carboxylic acid is prepared in a process involving chemical resolution of a racemic mixture of a trans-2,2-dichloro-3-(substituted phenyl)cyclopropanecarboxylic acid with an enantiomeric amine, isolation of a diastereomeric amine salt and finally treatment of the salt with an acid.

  2,2-二氯-3-(取代苯基)环丙烷羧酸的(1R,3R)-或(1S,3S)-对映体的制备过程包括反式-2,2-二氯-3-(取代苯基)环丙烷羧酸的外消旋混合物与对映体胺的化学分解，分离非对映胺盐，最后用酸处理该盐。
• Molecules having pesticidal utility, and intermediates, compositions, and processes related thereto
  申请人：Dow AgroSciences LLC

  公开号：US10993440B2

  公开（公告）日：2021-05-04

  This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”).

  本公开涉及对节肢动物门、软体动物门和线虫动物门害虫具有杀虫作用的分子、生产此类分子的工艺、用于此类工艺的中间体、含有此类分子的杀虫组合物以及使用此类杀虫组合物对付此类害虫的工艺。这些杀虫组合物可用作杀螨剂、杀虫剂、杀螨剂、杀软体动物剂和杀线虫剂等。本文公开了具有下式（"式一"）的分子。
• DUCHATEAU, A.;CROMBACH, M.;KAMPHUIS, J.;BOESTEN, W. H. J.;SCHOEMAKER, H. +, J. CHROMATOGR., 471,(1989) C. 263-270
  作者：DUCHATEAU, A.、CROMBACH, M.、KAMPHUIS, J.、BOESTEN, W. H. J.、SCHOEMAKER, H. +

  DOI：——

  日期：——
• KRUIZINGA, WIM H.;BOLSTER, JOHN;KELLOGG, RICHARD M.;KAMPHUIS, JOHAN;BOEST+, J. ORG. CHEM., 53,(1988) N 8, 1826-1827
  作者：KRUIZINGA, WIM H.、BOLSTER, JOHN、KELLOGG, RICHARD M.、KAMPHUIS, JOHAN、BOEST+

  DOI：——

  日期：——