N,N-dimethyl-2-(1H-pyrrol-1-yl)ethan-1-amine | 14798-67-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: N,N-dimethyl-2-(1H-pyrrol-1-yl)ethan-1-amine
• 英文别名: N,N-dimethyl-2-pyrrol-1-ylethanamine
• CAS: 14798-67-5
• 化学式: C₈H₁₄N₂
• mdl: MFCD12187088
• 分子量: 138.213
• InChiKey: MKAFXTJXBAATNI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  8.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N,N-dimethyl-2-(1H-pyrrol-1-yl)ethan-1-amine 、 碘甲烷 生成 trimethyl-(2-pyrrol-1-yl-ethyl)-ammonium; iodide
  参考文献：
  名称：

  The Synthesis of 1- and 2-Pyrrolealkylamines

  摘要：

  DOI：

  10.1021/jo01114a020
• 作为产物：
  描述：

  吡咯 、 2-氯-N,N-二甲基乙胺 在 sodium amide 、 苯 作用下， 生成 N,N-dimethyl-2-(1H-pyrrol-1-yl)ethan-1-amine
  参考文献：
  名称：

  The Synthesis of 1- and 2-Pyrrolealkylamines

  摘要：

  DOI：

  10.1021/jo01114a020

文献信息

• Use of Metal Complex Compounds as Oxidation Catalysts
  申请人：Schlingloff Gunther

  公开号：US20090044345A1

  公开（公告）日：2009-02-19

  The present invention relates to the use, as oxidation catalysts, of metal complex compounds having tetradentate ligands of formula (2) wherein all substitutents have the meanings as defined in Claim 1 . The present invention relates also to formulations comprising such metal complex compounds, to novel metal complex compounds and to novel ligands.

  本发明涉及将具有四齿配体的金属配合物化合物用作氧化催化剂，其化学式为（2），其中所有取代基的含义如权利要求1中定义的。本发明还涉及包含这种金属配合物化合物的配方，以及新型金属配合物和新型配体。
• Identification of Psychoplastogenic <i>N</i>,<i>N</i>-Dimethylaminoisotryptamine (isoDMT) Analogues through Structure–Activity Relationship Studies
  作者：Lee E. Dunlap、Arya Azinfar、Calvin Ly、Lindsay P. Cameron、Jayashri Viswanathan、Robert J. Tombari、Douglas Myers-Turnbull、Jack C. Taylor、Ana Cristina Grodzki、Pamela J. Lein、David Kokel、David E. Olson

  DOI：10.1021/acs.jmedchem.9b01404

  日期：2020.2.13

  Ketamine, N,N-dimethyltryptamine (DMT), and other psychoplastogens possess enormous potential as neurotherapeutics due to their ability to potently promote neuronal growth. Here, we report the first-ever structure activity relationship study with the explicit goal of identifying novel psychoplastogens. We have discovered several key features of the psychoplastogenic pharmacophore and used this information to develop N,N-dimethylaminoisotryptamine (isoDMT) psychoplastogens that are easier to synthesize, have improved physicochemical properties, and possess reduced hallucinogenic potential as compared to their DMT counterparts.
• LIGAND COMPOUND, CATALYST SYSTEM FOR OLEFIN OLIGOMERIZATION, AND OLEFIN OLIGOMERIZATION METHOD USING THE SAME
  申请人：LG CHEM, LTD.

  公开号：US20160271600A1

  公开（公告）日：2016-09-22

  The present invention relates to a ligand compound, a catalyst system for olefin oligomerization, and a method for olefin oligomerization using the same. The present ligand compound is a compound having a certain new structure and enables provision of a catalyst system for olefin oligomerization that can oligomerize ethylene with higher catalytic activity.
• US9827561B2
  申请人：——

  公开号：US9827561B2

  公开（公告）日：2017-11-28