2',6-dihydroxybiphenyl-3-carbonitrile | 1449679-50-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2',6-dihydroxybiphenyl-3-carbonitrile
• 英文别名: 4-Hydroxy-3-(2-hydroxyphenyl)benzonitrile
• CAS: 1449679-50-8
• 化学式: C₁₃H₉NO₂
• 分子量: 211.22
• InChiKey: LMNWCJVTDSJNQX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  64.2
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-溴-4-羟基氰苯 、 2-羟基苯硼酸 在 palladium 10% on activated carbon 、 potassium hydroxide 作用下， 以 水 为溶剂， 反应 0.5h， 以77%的产率得到2',6-dihydroxybiphenyl-3-carbonitrile
  参考文献：
  名称：

  2,2′-Biphenols via Protecting Group-Free Thermal or Microwave-Accelerated Suzuki–Miyaura Coupling in Water

  摘要：

  User-friendly protocols for the protecting group-free synthesis of 2,2'-biphenols via Suzuki-Miyaura coupling of o-halophenols and o-boronophenol are presented. The reactions proceed in water in the presence of simple additives such as K2CO3, KOH, KF, or TBAF and with commercially available Pd/C as precatalyst. Expensive or laboriously synthesized ligands or other additives are not required. In the case of bromophenols, efficient rate acceleration and short reaction times were accomplished by microwave irradiation.

  DOI：

  10.1021/jo401398n

文献信息

• COMPOUNDS AND MESOGENIC MEDIA
  申请人：MERCK PATENT GMBH

  公开号：US20160229795A1

  公开（公告）日：2016-08-11

  Disclosed are compounds of formula I the use of compounds of formula I in liquid crystal media and in particular to flexoelectric liquid crystal devices containing the liquid crystal media.

  公开的是公式I的化合物在液晶介质中的使用，特别是包含该液晶介质的柔性电液晶器件。
• Homogeneous electrorheological fluid
  申请人：Asahi Kasei Kogyo Kabushiki Kaisha

  公开号：EP0657526A2

  公开（公告）日：1995-06-14

  [Purpose] To provide a homogenous electrorheological fluid free from the problem of particles sedimentation. [Structure] An electrorheological fluid comprising, as a main component, a liquid crystal compound comprising a flexible molecular chain having at least two liquid crystal substances bonded thereto. [Effect] Being free from the problem of sedimentation of particles and therefore, it can be applied with stability for prolonged period of time to novel compact actuators handled with electric control such as valve, clutch, brake and torque convertor.

  [目的] 提供一种无颗粒沉淀问题的均匀电流变液。 [结构] 一种电流变液，其主要成分是液晶化合物，该液晶化合物由柔性分子链构成，分子链上至少键合有两种液晶物质。 [效果] 不存在颗粒沉积问题，因此可长期稳定地应用于新型电控紧凑型执行器，如阀门、离合器、制动器和扭矩转换器。
• Compounds and mesogenic media
  申请人：MERCK PATENT GMBH

  公开号：US10343982B2

  公开（公告）日：2019-07-09

  Disclosed are compounds of formula I the use of compounds of formula I in liquid crystal media and in particular to flexoelectric liquid crystal devices containing the liquid crystal media.

  公开了式 I 的化合物 式 I 化合物在液晶介质中的应用，特别是在含有该液晶介质的柔电液晶装置中的应用。
• Bimesogenic compounds and mesogenic media
  申请人：Merck Patent GmbH

  公开号：US10711196B2

  公开（公告）日：2020-07-14

  Bimesogenic compounds of formula I and their use in liquid crystal media and in flexoelectric liquid crystal devices.

  式 I 的生双酰胺化合物 及其在液晶介质和柔电液晶器件中的应用。
• Methods of making telechelic oligomers, methods of making block copolymers, and novel block copolymers
  申请人：——

  公开号：US20020115793A1

  公开（公告）日：2002-08-22

  A method of making telechelic oligomers comprises reacting a substrate compound selected from the group consisting of relatively high molecular weight polymers with a chain transfer agent in the presence of an alkali metal catalyst. The telechelic oligomers thus produced may then be reacted with monomers according to known polymerization techniques in order to produce block copolymers.

  制造远链低聚物的方法包括：在碱金属催化剂存在下，将选自相对高分子量聚合物 组的底物化合物与链转移剂进行反应。这样制得的远缘低聚物可根据已知的聚合技术与单体反应，以生产嵌段共聚物。