Butane-1,1-diol;3-hydroxybutanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羟基酸及其衍生物
• 英文名称: Butane-1,1-diol;3-hydroxybutanoic acid
• 英文别名: butane-1,1-diol;3-hydroxybutanoic acid
• 化学式: C8H18O5
• 分子量: 194.23
• InChiKey: YAIPYRLKGQPJCG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.06
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  98
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• Compound for use in protecting skin
  申请人：TDELTAS LIMITED

  公开号：US10821062B2

  公开（公告）日：2020-11-03

  A method of protecting animal tissue particularly skin, from damage caused by radiation exposure, by contacting the tissue with a ketone ester, a method of protecting skin, reducing the deterioration of skin or maintaining or improving the properties of skin by applying topically to the skin a ketone body comprising (R)-3-hydroxybutyrate moieties is disclosed. A ketone body comprising (R)-3-hydroxybutyrate moieties, especially enantiomerically enriched R-1,3-hydroxybutyl-(R)-3-hydroxybutyrate, for such uses is also provided.

  本发明公开了一种保护动物组织，特别是皮肤免受辐射照射损害的方法，方法是将酮酯与动物组织接触；还公开了一种保护皮肤的方法，方法是在皮肤上局部涂抹由(R)-3-羟基丁酸酯分子组成的酮体，以减少皮肤的恶化或保持或改善皮肤的特性。还提供了一种包含(R)-3-羟基丁酸分子的酮体，特别是对映体富集的 R-1,3-羟基丁基-(R)-3-羟基丁酸，用于上述用途。
• COMPOUND FOR USE IN PROTECTING SKIN
  申请人：Tdeltas Limited

  公开号：EP2968091A1

  公开（公告）日：2016-01-20
• [EN] COMPOUND FOR USE IN PROTECTING SKIN<br/>[FR] COMPOSÉ SERVANT À PROTÉGER LA PEAU
  申请人：TDELTAS LTD

  公开号：WO2014139599A1

  公开（公告）日：2014-09-18

  A method of protecting animal tissue particularly skin, from damage caused by radiation exposure, by contacting the tissue with a ketone ester, a method of protecting skin, reducing the deterioration of skin or maintaining or improving the properties of skin by applying topically to the skin a ketone body comprising (R)-3-hydroxybutyrate moieties is disclosed. A ketone body comprising (R)-3-hydroxybutyrate moieties, especially enantiomerically enriched R-1,3-hydroxybutyl-(R)-3-hydroxybutyrate, for such uses is also provided.