5-[2-methoxy-5-methyl-3-(4-methyl-5-oxo-penta-1,3-dienyl)-phenyl]-2-methyl-penta-2,4-dienal | 680575-43-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 5-[2-methoxy-5-methyl-3-(4-methyl-5-oxo-penta-1,3-dienyl)-phenyl]-2-methyl-penta-2,4-dienal
• 英文别名: (2E,4E)-5-[2-methoxy-5-methyl-3-[(1E,3E)-4-methyl-5-oxopenta-1,3-dienyl]phenyl]-2-methylpenta-2,4-dienal
• CAS: 680575-43-3
• 化学式: C₂₀H₂₂O₃
• 分子量: 310.393
• InChiKey: WAOCVCWHVXUROS-JKEPKXLBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  23
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  5-[2-methoxy-5-methyl-3-(4-methyl-5-oxo-penta-1,3-dienyl)-phenyl]-2-methyl-penta-2,4-dienal 在 camphor-10-sulfonic acid 、 zinc(II) chloride 作用下， 以 乙醚 为溶剂， 反应 36.0h， 生成 9-[3-(4,8-dimethyl-9-oxo-nona-1,3,5,7-tetraenyl)-2-methoxy-5-methyl-phenyl]-2,6-dimethyl-nona-2,4,6,8-tetraenal
  参考文献：
  名称：

  O-Trimethylsilylenol ethers as versatile building blocks in a modular preparation of polyenic backbone

  摘要：

  Versatility and synthetic potential of 1-(trimethylsilyloxy)-1,3-butadiene, 1-(trimethylsilyloxy)penta-1,3-diene, and their methyl substituted derivatives have been demonstrated in a modular synthetic methodology of stereodefined pi-conjugated unsymmetrical, symmetrical two-dimensional, and octupolar polyenal structure. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2003.12.008
• 作为产物：
  描述：

  2-甲氧基-5-甲基异邻苯二甲醛 在 camphor-10-sulfonic acid 、 zinc(II) chloride 作用下， 以 乙醚 为溶剂， 反应 38.5h， 生成 5-[2-methoxy-5-methyl-3-(4-methyl-5-oxo-penta-1,3-dienyl)-phenyl]-2-methyl-penta-2,4-dienal
  参考文献：
  名称：

  O-Trimethylsilylenol ethers as versatile building blocks in a modular preparation of polyenic backbone

  摘要：

  Versatility and synthetic potential of 1-(trimethylsilyloxy)-1,3-butadiene, 1-(trimethylsilyloxy)penta-1,3-diene, and their methyl substituted derivatives have been demonstrated in a modular synthetic methodology of stereodefined pi-conjugated unsymmetrical, symmetrical two-dimensional, and octupolar polyenal structure. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2003.12.008

文献信息

• O-Trimethylsilylenol ethers as versatile building blocks in a modular preparation of polyenic backbone
  作者：Beata W Domagalska、Ludwik Syper、Kazimiera A Wilk

  DOI：10.1016/j.tet.2003.12.008

  日期：2004.2

  Versatility and synthetic potential of 1-(trimethylsilyloxy)-1,3-butadiene, 1-(trimethylsilyloxy)penta-1,3-diene, and their methyl substituted derivatives have been demonstrated in a modular synthetic methodology of stereodefined pi-conjugated unsymmetrical, symmetrical two-dimensional, and octupolar polyenal structure. (C) 2004 Elsevier Ltd. All rights reserved.