(2S,3S,4R)-2-azido-3,4-bis[(4-methoxyphenyl)methyl]octadecan-1-ol

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物 - 二苄基丁烷木脂素
• 英文名称: (2S,3S,4R)-2-azido-3,4-bis[(4-methoxyphenyl)methyl]octadecan-1-ol
• 化学式: C34H53N3O3
• 分子量: 551.8
• InChiKey: DCBNSCNMZIQFBC-SAUDROSCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.4
• 重原子数：
  40
• 可旋转键数：
  23
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  53
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Highly efficient synthesis of alpha-O-galactosyl ceramides
  申请人：Gervay-Hague Jacquelyn

  公开号：US20090036658A1

  公开（公告）日：2009-02-05

  A method for the production of a-O-galactosyl ceramide precursor is demonstrated. The method involves the reaction of galactosyl iodide with a sphingosine derivative or phytosphingosine derivative in the presence of a quaternary ammonium iodide salt to prepare the a-O-galactosyl ceramide precursor in the a-anomer form. The a-O-galactosyl ceramide is then prepared by reaction with a suitable fatty acid or fatty acid derivative.