Methyl 2,2-dihydroxyoctadecanoate | 67332-37-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Methyl 2,2-dihydroxyoctadecanoate
• CAS: 67332-37-0
• 化学式: C₁₉H₃₈O₄
• 分子量: 330.5
• InChiKey: RWZVFCIPMBYBCY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  23
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• [EN] CONTINUOUS PROCESS FOR THE PRODUCTION OF DERIVATIVES OF SATURATED CARBOXYLIC ACIDS<br/>[FR] PROCÉDÉ CONTINU DE PRODUCTION DE DÉRIVÉS D'ACIDES CARBOXYLIQUES SATURÉS
  申请人：NOVAMONT SPA

  公开号：WO2011080297A1

  公开（公告）日：2011-07-07

  There is described a continuous process for the oxidative cleavage of derivatives of unsaturated carboxylic acids for the production of saturated carboxylic acids and their derivatives comprising the steps of: a) feeding to a first reactor at least a derivative of an unsaturated carboxylic acid, an oxidizing compound and a catalyst capable of catalyzing the oxidation reaction of the olefinic double bond to obtain an intermediate compound containing vicinal diols, and of b) feeding to a second reactor said intermediate compound, a compound containing oxygen and a catalyst capable of catalyzing the oxidation reaction of the vicinal diols to carboxylic groups, to obtain saturated monocarboxylic acids (i) and derivatives of saturated carboxylic acids with more than one acid function (ii); c) separating the saturated monocarboxylic acids (i) from the derivatives of carboxylic acids having more than one acid function (ii).

  描述了一种连续的过程，用于氧化裂解不饱和羧酸衍生物，生产饱和羧酸及其衍生物，包括以下步骤：a）将至少一种不饱和羧酸衍生物、氧化剂和能够催化烯烃双键氧化反应的催化剂输入到第一反应器中，以获得含有邻二醇的中间化合物；b）将所述中间化合物、含氧化合物和能够催化邻二醇氧化为羧基的催化剂输入到第二反应器中，以获得饱和单羧酸（i）和具有多个酸功能的饱和羧酸衍生物（ii）；c）将饱和单羧酸（i）与具有多个酸功能的羧酸衍生物（ii）分离。
• CONTINUOUS PROCESS FOR THE PRODUCTION OF DERIVATIVES OF SATURATED CARBOXYLIC ACIDS
  申请人：Bieser Arno

  公开号：US20120302778A1

  公开（公告）日：2012-11-29

  There is described a continuous process for the oxidative cleavage of derivatives of unsaturated carboxylic acids for the production of saturated carboxylic acids and their derivatives comprising the steps of: a) feeding to a first reactor at least a derivative of an unsaturated carboxylic acid, an oxidizing compound and a catalyst capable of catalyzing the oxidation reaction of the olefinic double bond to obtain an intermediate compound containing vicinal diols, and of b) feeding to a second reactor said intermediate compound, a compound containing oxygen and a catalyst capable of catalyzing the oxidation reaction of the vicinal diols to carboxylic groups, to obtain saturated monocarboxylic acids (i) and derivatives of saturated carboxylic acids with more than one acid function (ii); c) separating the saturated monocarboxylic acids (i) from the derivatives of carboxylic acids having more than one acid function (ii).

  描述了一种连续过程，用于氧化裂解不饱和羧酸衍生物以生产饱和羧酸及其衍生物，包括以下步骤：a）将至少一种不饱和羧酸衍生物、氧化剂和能够催化烯丙双键氧化反应的催化剂送入第一反应器，以获得含有邻二醇的中间化合物，和b）将所述中间化合物、含氧化合物和能够催化邻二醇氧化为羧基的催化剂送入第二反应器，以获得饱和单羧酸（i）和具有多个酸功能的饱和羧酸衍生物（ii）；c）将饱和单羧酸（i）与具有多个酸功能的羧酸衍生物（ii）分离。
• Improved Process for the Production of Derivatives of Saturated Carboxylic Acids
  申请人：Bastioli Catia

  公开号：US20080245995A1

  公开（公告）日：2008-10-09

  A process for the production of carboxylic acids and their derivatives comprising the steps of: (c) reacting a derivative of an unsaturated fatty acid with an oxidizing compound in the presence of a catalyst capable of catalysing the reaction of oxidation of the double olefinic bond of the derivative of the unsaturated fatty acid so as to obtain as intermediate product of reaction a vicinal diol; and (d) reacting said intermediate compound with oxygen, or a compound containing oxygen, in the presence of a catalyst capable of catalysing the reaction of oxidation of the hydroxyl groups of the vicinal diol to carboxylic groups, characterized in that both of the steps (a) and (b) are carried out in the absence of added organic solvent and in that the water/diol ratio in the reaction of step (b) is less than 1:1.

  一种生产羧酸及其衍生物的方法，包括以下步骤：（c）在催化剂的存在下，将不饱和脂肪酸衍生物与氧化剂反应，催化剂能够催化不饱和脂肪酸衍生物的双烯键氧化反应，从而得到邻二醇的中间产物；（d）在催化剂的存在下，将该中间化合物与氧气或含氧化合物反应，催化剂能够催化邻二醇的羟基氧化反应成为羧基，其特征在于步骤（a）和（b）都在无添加有机溶剂的情况下进行，并且步骤（b）中的水/二醇比小于1:1。
• Process for the oxidative cleavage of vicinal diols
  申请人：NOVAMONT S.P.A.

  公开号：US10421925B2

  公开（公告）日：2019-09-24

  This invention relates to a process for obtaining monocarboxylic and dicarboxylic acids from unsaturated carboxylic acids and/or their derivatives. The said process comprises an oxidative cleavage reaction of vicinal diols into which are fed at least some of the aqueous phase separated out at the end of the reaction itself and at least one base so that the pH of the aqueous solution at the start of the oxidative cleavage reaction is between 4 and 7.

  本发明涉及一种从不饱和羧酸和/或其衍生物中获得单羧酸和二羧酸的工艺。该工艺包括邻位二元醇的氧化裂解反应，向该反应中加入至少一些在反应本身结束时分离出来的水相和至少一种碱，从而使氧化裂解反应开始时水溶液的 pH 值介于 4 和 7 之间。
• OLIGOMERS OF FATTY ACIDS
  申请人：UNICHEMA CHEMIE B.V.

  公开号：EP0984916A1

  公开（公告）日：2000-03-15