3-(2-nitro-phenoxy)-benzoic acid | 27237-20-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(2-nitro-phenoxy)-benzoic acid
• 英文别名: 3-(2-Nitro-phenoxy)-benzoesaeure；3-(2-Nitrophenoxy)benzoic acid
• CAS: 27237-20-3
• 化学式: C₁₃H₉NO₅
• mdl: MFCD00690139
• 分子量: 259.218
• InChiKey: HGFIGLCYOONRCT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  92.4
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  3-(2-nitro-phenoxy)-benzoic acid 在 氯化亚砜 、 氨 、 丙酮 、 苯 作用下， 生成 3-(2-nitro-phenoxy)-benzoic acid amide
  参考文献：
  名称：

  Expression of human hepatitis C virus core antigen in tobacco plants by tobacco mosaic virus-based vector system

  摘要：

  Tobacco mosaic virus (TMV) has the potential to highly express foreign gene. A novel TMV-based in trans expression system was constructed. A TMV mutant TSHc had its coat protein replaced with hepatitis C virus (HCV) core antigen gene. Another TMV mutant TSBD was replicase-detective. Coinfection of the two mutants could cause systemic infection in tobacco plants by in trans complementation of their functions. TSHc could effectively replicate and assemble to viral particles, which were a little longer than that of wild-type TMV. HCV core antigen was expressed in whole tobacco plants. A similar expression lever of HCV core antigen was detected on serial passages, which suggested that this viral expression system be stable.

  DOI：

  10.1007/bf02884901
• 作为产物：
  描述：

  2-(3-methylphenoxy)nitrobenzene 在 potassium permanganate 作用下， 生成 3-(2-nitro-phenoxy)-benzoic acid
  参考文献：
  名称：

  Tomita; Ikawa, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1955, vol. 75, p. 449,451

  摘要：

  DOI：

文献信息

• Method of Treating Kcnq Related Disorders Using Organozinc Compounds
  申请人：Li Min

  公开号：US20110257146A1

  公开（公告）日：2011-10-20

  The instant invention describes methods of treating KCNQ related diseases and disorders using organozinc compounds. In certain embodiments, pain is treated using Zinc Pyrithione.
• US4874846A
  申请人：——

  公开号：US4874846A

  公开（公告）日：1989-10-17
• Tomita; Ikawa, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1955, vol. 75, p. 449,451
  作者：Tomita、Ikawa

  DOI：——

  日期：——
• Expression of human hepatitis C virus core antigen in tobacco plants by tobacco mosaic virus-based vector system
  作者：Aidong Han、Yule Liu、Li Xiao、Liangyi Kang、Yuman Zhang、Dongtian Li、Bo Tian

  DOI：10.1007/bf02884901

  日期：2000.3

  Tobacco mosaic virus (TMV) has the potential to highly express foreign gene. A novel TMV-based in trans expression system was constructed. A TMV mutant TSHc had its coat protein replaced with hepatitis C virus (HCV) core antigen gene. Another TMV mutant TSBD was replicase-detective. Coinfection of the two mutants could cause systemic infection in tobacco plants by in trans complementation of their functions. TSHc could effectively replicate and assemble to viral particles, which were a little longer than that of wild-type TMV. HCV core antigen was expressed in whole tobacco plants. A similar expression lever of HCV core antigen was detected on serial passages, which suggested that this viral expression system be stable.