Methenamine anhydromethylenecitrate | 6190-43-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Methenamine anhydromethylenecitrate
• 英文别名: 2-[4-(carboxymethyl)-5-oxo-1,3-dioxolan-4-yl]acetic acid;1,3,5,7-tetrazatricyclo[3.3.1.13,7]decane
• CAS: 6190-43-8
• 化学式: C13H20N4O7
• 分子量: 344.32
• InChiKey: VFYFMNCKPJDAPV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.81
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  123
• 氢给体数：
  2
• 氢受体数：
  11

文献信息

• Flexible bone composite
  申请人：Synthes USA

  公开号：EP2308517A2

  公开（公告）日：2011-04-13

  The present invention relates in general to implantable flexible bone composites, and method for preparing the same. The flexible bone composite includes at least one polymeric layer and at least one calcium-containing layer. The polymeric layer can be a polymeric layer including a synthetic polymer. The calcium-containing layer can include a calcium compound such as β-Ca3(PO4)?. The flexible bone composites of the invention are useful as bone void fillers and have improved handling characteristics.

  本发明总体上涉及可植入的柔性骨复合材料及其制备方法。柔性骨复合材料包括至少一个聚合物层和至少一个含钙层。聚合物层可以是包括合成聚合物的聚合物层。含钙层可包括钙化合物，如β-Ca3(PO4)?本发明的柔性骨复合材料可用作骨空隙填充物，并具有更好的处理特性。
• Functional surfaces
  申请人：Orthobond Corporation

  公开号：US11154061B2

  公开（公告）日：2021-10-26

  Articles having functional surfaces, for example antimicrobial functional surfaces, are prepared by methods comprising anodization. Organophosphorous compounds are deposited on a surface by methods comprising anodization, followed by attaching functional compounds, functional oligomers or functional polymers. Alternatively, functional organophosphorous compounds, functional oligomers or functional polymers are deposited on a surface by methods comprising anodization.

  具有功能性表面（例如抗菌功能性表面）的物品是通过包括阳极氧化的方法制备的。有机磷化合物可通过阳极氧化法沉积在表面上，然后再附着功能性化合物、功能性低聚物或功能性聚合物。或者，通过阳极氧化法在表面沉积功能性有机磷化合物、功能性低聚物或功能性聚合物。
• Antimicrobial hyaluronic acid coatings for orthopedic implants
  申请人：Disegi Arthur John

  公开号：US20050220837A1

  公开（公告）日：2005-10-06

  The invention relates to an implant wherein the surface of the implant is coated with hyaluronic acid or a derivative thereof. The coated implants resist microbial growth.

  本发明涉及一种植入物，其表面涂有透明质酸或其衍生物。 这种涂层植入物可防止微生物生长。
• Devices with multiple surface functionality
  申请人：Schwartz Jeffrey

  公开号：US20060194008A1

  公开（公告）日：2006-08-31

  Phosphorus-based coatings having a plurality of phosphate moieties, a plurality of phosphonate moieties, or both, covalently bonded to an oxide surface of an implantable substrate exhibiting one or more of the following characteristics: (a) the surface phosphorus-containing group density of the coated regions of the substrate is at least about 0.1 nmol/cm 2 ; (b) the phosphorus-based coating has a thickness of less than about 10 nm; or (c) the surface phosphorus-containing group density of the coated regions of the substrate is equal to or greater than the surface hydroxyl group density of the oxide surface of the substrate. Implantable devices embodying the coated substrates are also disclosed.

  具有多个磷酸基、多个膦酸基或二者共价键合到可植入基底的氧化物表面的磷基涂层，具有以下一个或多个特征： (a) 基底涂层区域的表面含磷基团密度至少约为 0.1 nmol/cm 2 (b) 磷基涂层的厚度小于约 10 nm；或 (c) 基底涂层区域的表面含磷基团密度等于或大于基底氧化物表面的表面羟基密度。还公开了体现涂层基底的可植入装置。
• FAST DISSOLVING COMPOSITION WITH PROLONGED SWEET TASTE
  申请人：Panacea Biotec Limited

  公开号：EP1235561A2

  公开（公告）日：2002-09-04