Propyl 2,2-di(hydroxymethyl)propionate | 63468-00-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羟基酸及其衍生物
• 英文名称: Propyl 2,2-di(hydroxymethyl)propionate
• 英文别名: propyl 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate
• CAS: 63468-00-8
• 化学式: C₈H₁₆O₄
• 分子量: 176.21
• InChiKey: WKKSVSCQYZLNJY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Derivatives of curcuminoids and use thereof as an anticancer agent
  申请人：CHINA MEDICAL UNIVERSITY

  公开号：US10787413B2

  公开（公告）日：2020-09-29

  A series of novel bis(hydroxymethyl) alkanoate derivatives of curcuminoids were designed, and synthesized, which show anticancer activity, and in particular to breast cancer, colon cancer, and prostate cancer.

  我们设计并合成了一系列新型姜黄素双（羟甲基）烷酸酯衍生物，这些衍生物具有抗癌活性，特别是对乳腺癌、结肠癌和前列腺癌。
• BLOCK COPOLYMERS WITH SURFACE-ACTIVE JUNCTION GROUPS, COMPOSITIONS AND PROCESSES THEREOF
  申请人：IBM Corporation

  公开号：US20160244557A1

  公开（公告）日：2016-08-25

  The present invention relates to a novel block copolymer of structure 1, wherein, A- is a block polymer chain, B is a block polymer chain, wherein, A- and B- are chemically different, covalently connected polymer chains, which are phase separable and the moiety X(Y(Z) b ) a is a junction group, which comprises a surface active pendant moiety Y(Z) b wherein: a is an integer from 1 to 4 denoting the number of surface active pendant moieties Y(Z) b on X, b is an integer from 1 to 5 denoting the number of Z moieties on the linking moiety Y, X is a linking group between the A polymer block, the B polymer block and the moiety Y, Y is a linking group or a direct valence bond between X and Z; and Z is a moiety independently selected from, a fluorine containing moiety, a Si 1 -Si 8 siloxane containing moiety or a hydrocarbon moiety with at least 18 carbons, and further wherein the junction group X(Y(Z) b ) a has a surface energy less than that that of the block A and less than that of the block B. The invention also relates to a composition comprising the novel copolymer and its use in direct self-assembly processes.
• HIGH-CHI BLOCK COPOLYMERS FOR INTERCONNECT STRUCTURES BY DIRECTED SELF-ASSEMBLY
  申请人：International Business Machines Corporation

  公开号：US20170294341A1

  公开（公告）日：2017-10-12

  High-chi diblock copolymers are disclosed whose self-assembly properties are suitable for forming hole and bar openings for conductive interconnects in a multi-layered structure. The hole and bar openings have reduced critical dimension, improved uniformity, and improved placement error compared to the industry standard poly(styrene)-b-poly(methyl methacrylate) block copolymer (PS-b-PMMA). The BCPs comprise a poly(styrene) block, which can optionally include repeat units derived from trimethylsilyl styrene, and a second block that can be a polycarbonate block or a polyester block. Block copolymers comprising a fluorinated linking group L′ comprising 1-25 fluorines between the blocks can provide further improvement in uniformity of the openings.
• NOVEL DERIVATIVES OF CURCUMINOIDS AND USE THEREOF AS AN ANTICANCER AGENT
  申请人：CHINA MEDICAL UNIVERSITY

  公开号：US20190161430A1

  公开（公告）日：2019-05-30

  A series of novel bis(hydroxymethyl) alkanoate derivatives of curcuminoids were designed, and synthesized, which show anticancer activity, and in particular to breast cancer, colon cancer, and prostate cancer.
• US4742095A
  申请人：——

  公开号：US4742095A

  公开（公告）日：1988-05-03