diacetyl adipate | 38478-77-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: diacetyl adipate
• 英文别名: Hexanedioic acid, dianhydride with acetic acid；diacetyl hexanedioate
• CAS: 38478-77-2
• 化学式: C₁₀H₁₄O₆
• 分子量: 230.218
• InChiKey: RFANYEWAHJJLAD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  16
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  86.7
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  己二酸 、 乙酸酐 反应 0.33h， 生成 diacetyl adipate
  参考文献：
  名称：

  Synthesis and characterization of copolyanhydrides of carbohydrate-based galactaric acid and adipic acid

  摘要：

  A series of copolyanhydrides, consisting of 2,3,4,5-tetra-O-acetylgalactaric acid (AGA) and adipic acid (AA) as monomer units, was polymerized. Synthesis of AGA monomer consisted of two steps. First, O-acetylation of galactaric acid secondary hydroxyl groups was performed using acetic anhydride as a reagent. Acetic anhydride was then further used as a reagent in the synthesis of diacetyl mixed anhydride of AGA. Polymerizations were conducted as bulk condensation polymerization at 150 degrees C. Thermal properties of the copolymers varied depending on monomer composition. Increase in the AGA content had a clear increasing effect on the T-g. A similar increasing effect was observed in T-m. The degree of crystallinity decreased as AGA content increased. There was a slightly lowering tendency in the molecular weights of the obtained polymers when the AGA content in the polymerization mixtures increased. The described synthesis route shows that bio-based aldaric acid monomers are potential candidates for the adjustment of thermal properties of polyanhydrides. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2014.07.009

文献信息

• CELLULOSE DERIVATIVES FOR INHIBITING CRYSTALLIZATION OF POORLY WATER-SOLUBLE DRUGS
  申请人：Virginia Tech Intellectual Properties, Inc.

  公开号：US20150004237A1

  公开（公告）日：2015-01-01

  Provided are cellulose esters useful for inhibiting solution crystallization of drugs. Specific polymers include cellulose esters of formula I: wherein n of the ω-carboxyalkanoyl group, is 3, 4, 6, or 8 to provide a ω-carboxyalkanoyl group chosen from succinoyl, glutaroyl, adipoyl, sebacyl, and suberyl groups; and wherein R is chosen from: a hydrogen atom; and an alkanoyl group chosen from acetyl, propionyl, butyryl, valeroyl, hexanoyl, nonanoyl, decanoyl, lauroyl, palmitoyl, and stearoyl groups; wherein there is a total degree of substitution of the alkanoyl group and the ω-carboxyalkanoyl group of at least 2.0; and wherein the polymer comprises m repeating units where n=1 to 1,000,000, or 10 to 100,000, or 100 to 1,000, such as 1 to 6,000. Embodiments further include compositions comprising cellulose esters and poorly water-soluble drugs, which compositions exhibit greater solubility and stability in solution as compared to the drugs alone.

  提供了对于抑制药物溶液结晶有用的纤维素酯。具体的聚合物包括式I的纤维素酯：其中ω-羧基烷酰基团的n为3、4、6或8，以提供从琥珀酰基、戊二酰基、己二酰基、癸二酰基和壬二酰基羧基烷酰基中选择的ω-羧基烷酰基；R从氢原子和从乙酰基、丙酰基、丁酰基、戊酰基、己酰基、壬酰基、癸酰基、月桂酰基、棕榈酰基和硬脂酰基羧酸基中选择的脂肪酰基中选择；其中脂肪酰基和ω-羧基烷酰基的总取代度至少为2.0；聚合物包括m个重复单元，其中n为1至1,000,000、10至100,000或100至1,000，例如1至6,000。实施例还包括包含纤维素酯和难溶于水的药物的组合物，该组合物在溶液中与药物单独相比表现出更高的溶解度和稳定性。
• Food coating
  申请人：Coöperative Verkoop- en Productievereniging, van Aardappelmeel en Derivaten Avebe B.A.

  公开号：EP1228700A1

  公开（公告）日：2002-08-07

  The present invention pertains to the use of a degraded and crosslinked starch in a food coating or batter composition for food products. Surprisingly, it has been found that by virtue of the use of this specific starch, the textural properties and in particular the crispiness of a coating on a food product are significantly improved.

  本发明涉及一种降解交联淀粉在食品涂层或食品面糊组合物中的使用。令人惊奇的是，通过使用这种特定的淀粉，食品涂层的质地特性，特别是酥脆度得到了显著改善。
• 3D-BIOPRINTING OF CELL-LADEN-COLLAGEN GELLAN GUM INTERPENETRATING NETWORK HYDROGEL
  申请人：ROQUETTE FRERES

  公开号：EP4098286A1

  公开（公告）日：2022-12-07

  The present invention relates to a method for preparing cell-laden gellan gum-collagen interpenetrating hydrogel using 3D-bioprinter and a 3D printed hydrogel obtainable thereof, particularly for use in the wound treatment.

  本发明涉及一种利用三维生物打印机制备含细胞的结冷胶-胶原互穿水凝胶的方法及其可获得的三维打印水凝胶，特别是用于伤口治疗的水凝胶。
• Carboxylic acid-modified nitrile-based copolymer latex, method for preparing same, latex composition for dip molding containing same, and dip-molded article
  申请人：LG Chem, Ltd.

  公开号：US10703884B2

  公开（公告）日：2020-07-07

  The present invention relates to a carbonic acid-modified nitrile-based copolymer latex, a process for producing the same, a latex composition for dip-molding comprising the latex composition and a molded article produced therefrom. More specifically, modified nitrile-based copolymer latex, which can improve the stability of latex even with the use of inorganic pigments by making the inherently modified nitrile-based copolymer latex, enables the production of a dip-molded article having a smoothness of syneresis, less stickiness, and excellent tensile strength, a process for producing the same, a latex composition for dip-molding comprising the same, and a molded article made therefrom.

  本发明涉及一种碳酸改性腈基共聚物胶乳、生产该胶乳的工艺、包含该胶乳组合物的用于浸塑成型的胶乳组合物以及由其制成的成型制品。更具体地说，改性腈基共聚物胶乳通过制造固有改性腈基共聚物胶乳，即使在使用无机颜料的情况下也能提高胶乳的稳定性，从而能够生产出具有平滑的粘滞性、较少的粘性和出色的拉伸强度的浸塑制品、生产该制品的工艺、包含该制品的浸塑用胶乳组合物以及由其制成的模塑制品。
• Verfahren zur Herstellung einer mayonnaiseartigen Emulsion
  申请人：KRAFT GENERAL FOODS R & D, INC., Zweigniederlassung München

  公开号：EP0386336B1

  公开（公告）日：1993-07-07