bis[4-(3,5-dichloro)pyridyl]ketimine | 847446-22-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: bis[4-(3,5-dichloro)pyridyl]ketimine
• 英文别名: Bis(3,5-dichloropyridin-4-yl)methanimine；bis(3,5-dichloropyridin-4-yl)methanimine
• CAS: 847446-22-4
• 化学式: C₁₁H₅Cl₄N₃
• 分子量: 320.993
• InChiKey: ZOURSSTVDZMWKJ-UHFFFAOYSA-N

物化性质

• 沸点：
  413.4±45.0 °C(Predicted)
• 密度：
  1.63±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  49.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  bis[4-(3,5-dichloro)pyridyl]ketimine 在 sodium acetate 、 dinitrogen tetraoxide 作用下， 以 四氯化碳 、 乙醚 为溶剂， 反应 3.0h， 生成 bis[4-(3,5-dichloro)pyridyl]diazomethane
  参考文献：
  名称：

  Preparation of Sterically Congested Di(4-pyridyl)diazomethanes and Characterization of Triplet Carbenes from Them

  摘要：

  Di(4-pyridyl)diazomethanes having two and four ortho chlorine groups were prepared, and the triplet carbenes generated from them were characterized by ESR and UV/vis at low temperature and time-resolved UV/vis at room temperature. An appreciable increase in the stability of triplet carbenes is achieved by introducing ortho chlorine groups.

  DOI：

  10.1021/ol047467p
• 作为产物：
  描述：

  3,5-二氯吡啶 在 sodium azide 、 三乙胺 、 lithium diisopropyl amide 作用下， 以 四氢呋喃 、 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 52.0h， 生成 bis[4-(3,5-dichloro)pyridyl]ketimine
  参考文献：
  名称：

  Preparation of Sterically Congested Di(4-pyridyl)diazomethanes and Characterization of Triplet Carbenes from Them

  摘要：

  Di(4-pyridyl)diazomethanes having two and four ortho chlorine groups were prepared, and the triplet carbenes generated from them were characterized by ESR and UV/vis at low temperature and time-resolved UV/vis at room temperature. An appreciable increase in the stability of triplet carbenes is achieved by introducing ortho chlorine groups.

  DOI：

  10.1021/ol047467p

文献信息

• Preparation of Sterically Congested Di(4-pyridyl)diazomethanes and Characterization of Triplet Carbenes from Them
  作者：Tetsuji Itoh、Akira Takada、Katsuyuki Hirai、Hideo Tomioka

  DOI：10.1021/ol047467p

  日期：2005.3.1

  Di(4-pyridyl)diazomethanes having two and four ortho chlorine groups were prepared, and the triplet carbenes generated from them were characterized by ESR and UV/vis at low temperature and time-resolved UV/vis at room temperature. An appreciable increase in the stability of triplet carbenes is achieved by introducing ortho chlorine groups.