2-hydroxyethyl (Z)-2,3-dichloroprop-2-enoate | 1392201-96-5

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 乙烯基卤化物
• 英文名称: 2-hydroxyethyl (Z)-2,3-dichloroprop-2-enoate
• CAS: 1392201-96-5
• 化学式: C₅H₆Cl₂O₃
• 分子量: 185.007
• InChiKey: RFDHYQMPXHYGDJ-ARJAWSKDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  (2Z)-2,3-二氯丙烯酸 、 乙二醇 在 N,N'-二环己基碳二亚胺 作用下， 生成 2-hydroxyethyl (Z)-2,3-dichloroprop-2-enoate
  参考文献：
  名称：

  Preparation of (Z)-1,2-dichloroalkenes from terminal alkynes

  摘要：

  (Z)-1,2-二卤代烯烃是两种立体异构体中热力学上不受青睐的。本文报告了从黏液氯酸合成一些(Z)-1,2-二氯代烯烃类似物的方法。更通用的方法是通过氯硼化末端炔烃来获得相应的(Z)-氯硼酸作为第一步。将有机硼酸与氟化氢钾处理，然后再用四丁基铵三氯化物处理，以立体特异性的方式中等到良好的产率获得(Z)-1,2-二氯代烯烃。

  DOI：

  10.1139/v2012-041

文献信息

• CONSUMER PRODUCT COMPRISING POLY ACRYLATE AND POLY(BETA-AMINO ESTER) DELIVERY CAPSULES WITH ENHANCED DEGRADABILITY
  申请人：The Procter & Gamble Company

  公开号：EP4000725A1

  公开（公告）日：2022-05-25

  Consumer product composition having delivery particles encapsulating oily core materials have a shell material of hybrid poly acrylate and poly(beta-amino esters) (PAC/PBAE). The delivery particles may have a single shell of hybrid PAC/PBAE, dual shells including hybrid PAC/PBAE in an inner shell and PBAE in an outer shell crosslinked to the inner shell, or multiple shells including PAC in an inner shell, hybrid PAC/PBAE in a transitioning shell, and PBAE in an outer shell. Formation of the delivery particles includes polymerization between multifunctional amine and multifunctional acrylate to produce a water-soluble PBAE; polymerization between the preformed PBAE prepolymer having free methacrylate moieties reactive with a multifunctional (meth)acrylate in the oil phase, or at an interface of the water and oil phases to produce PAC wall, polymerization between polyacrylate and the amine moiety of PBAE prepolymer to produce hybrid PAC/PBAE delivery particle wall; and polymerization between multifunctional acrylate and primary or secondary amine moiety of the PBAE prepolymer to form a PBAE outer shell.

  具有封装油性核心材料的输送颗粒的消费品组合物，其外壳材料为混合聚丙烯酸酯和聚（β-氨基酯）（PAC/PBAE）。递送颗粒可以是混合 PAC/PBAE 的单层壳，也可以是双层壳，包括内层壳中的混合 PAC/PBAE 和外层壳中与内层壳交联的 PBAE，还可以是多层壳，包括内层壳中的 PAC、过渡层中的混合 PAC/PBAE 和外层壳中的 PBAE。输送颗粒的形成包括多功能胺和多功能丙烯酸酯之间的聚合，以产生水溶性 PBAE；具有游离甲基丙烯酸酯分子的预成型 PBAE 预聚物与油相中或水相和油相界面处的多功能（甲基）丙烯酸酯反应聚合，生成 PAC 壁，聚丙烯酸酯与 PBAE 预聚物的胺分子聚合，生成混合 PAC/PBAE 输送粒子壁；以及多功能丙烯酸酯与 PBAE 预聚物的伯胺或仲胺分子聚合，形成 PBAE 外壳。
• Encapsulation
  申请人：Encapsys, LLC

  公开号：US20200315931A1

  公开（公告）日：2020-10-08

  The invention describes a core shell microcapsule wherein the capsule shell is hydrolysable. The capsule is made from a water phase with initiator and emulsifier, and from one or more oil phases having a first multifunctional (meth)acrylate monomer having greater than one ester group on average in the monomer and having a hydrophilicity index of less than 20; a second multifunctional (meth)acrylate monomer, the second multifunctional (meth)acrylate comprising a hydrophilic multifunctional polar monomer having a hydrophilicity index of at least 20 and said second multifunctional polar monomer comprising 50% or less of the capsule shell along with an acidic (meth)acrylate monomer or at least one oil soluble or dispersible simple acid, the acidic (meth)acrylate monomer having one or more groups which are selected from carboxy and sulfonic groups, and optionally from 0 to 50% by weight of the shell comprises in addition an aliphatic polyester comprising an oligomer, polymer or co-polymer of one or more of lactic acid, caprolactone, or glycolic acid, the aliphatic polyester having two or more of acrylate or methacrylate groups.
• MULTIFUNCTIONAL (METH)ACRYLATE POLYSACCHARIDE MICROCAPSULES
  申请人：Encapsys, LLC

  公开号：US20220087944A1

  公开（公告）日：2022-03-24

  The invention describes a core shell microcapsule wherein the capsule shell is an interfacial copolymer formed of a modified polysaccharide free radical cross-linked with a multifunctional (meth)acrylate. The polysaccharide is hydrophobically modified with an adduct containing at least one unsaturated bond. The modification imparts hydrophobic character to the polysaccharide to act as an emulsifier, driving the modified polysaccharide to an oil-water interface of an encapsulation emulsion described, and creates an active bonding site for free-radical polymerization between the polysaccharide and multifunctional (meth)acrylate, thereby forming a microcapsule shell surrounding the core material.
• Poly Acrylate and Poly(Beta-Amino Ester) Capsules with Enhanced Degradability
  申请人：Encapsys,LLC

  公开号：US20220153901A1

  公开（公告）日：2022-05-19

  Delivery particles encapsulating oily core materials have a shell material of hybrid poly acrylate and poly(beta-amino esters) (PAC/PBAE). The delivery particles may have a single shell of hybrid PAC/PBAE, dual shells including hybrid PAC/PBAE in an inner shell and PBAE in an outer shell crosslinked to the inner shell, or multiple shells including PAC in an inner shell, hybrid PAC/PBAE in a transitioning shell, and PBAE in an outer shell. Formation of the delivery particles includes polymerization between multifunctional amine and multifunctional acrylate to produce a water soluble PBAE; polymerization between the preformed PBAE prepolymer having free methacrylate moieties reactive with a multifunctional (meth)acrylate in the oil phase, or at an interface of the water and oil phases to produce PAC wall, polymerization between polyacrylate and the amine moiety of PBAE prepolymer to produce hybrid PAC/PBAE delivery particle wall; and polymerization between multifunctional acrylate and primary or secondary amine moiety of the PBAE prepolymer to form a PBAE outer shell.
• US3992014A
  申请人：——

  公开号：US3992014A

  公开（公告）日：1976-11-16