2,6-dimethoxybenzoyldiphenylphosphine oxide | 75980-61-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,6-dimethoxybenzoyldiphenylphosphine oxide
• 英文别名: (2,6-Dimethoxyphenyl)(diphenylphosphoryl)methanone；(2,6-dimethoxyphenyl)-diphenylphosphorylmethanone
• CAS: 75980-61-9
• 化学式: C₂₁H₁₉O₄P
• 分子量: 366.353
• InChiKey: SUEDCWGEKSLKOM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  二苯基膦 、 2,6-二甲氧基苯甲醛 在 二叔丁基过氧化物 、 copper diacetate 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 12.0h， 以89%的产率得到2,6-dimethoxybenzoyldiphenylphosphine oxide
  参考文献：
  名称：

  光固化引发剂酰基膦氧化合物的制备方法

  摘要：

  本发明提供一种式I所示的酰基膦氧化合物的制备方法，所述制备方法包括：(1)向式II所示的芳基甲醛衍生物与二芳基磷氧的混合物中加入Cu(OAc)2、过氧二叔丁基醚和溶剂，密封后在70～90℃下搅拌反应6～24小时得到反应液；(2)将反应液中的溶剂除去后，用二氯甲烷与水的混合溶剂进行萃取分离，收集下层有机相并除去溶剂得到粗产品，将粗产品纯化即得到式I所示的酰基膦氧化合物。该制备方法的中间产物无需分离，整个制备过程无需加入强酸或强碱作为溶剂，采用一锅法制备酰基膦氧化合物，制备工艺简单。

  公开号：

  CN114106040B

文献信息

• SILANE COUPLING COMPOUNDS AND MEDICAL AND/OR DENTAL CURABLE COMPOSITIONS COMPRISING THE SAME
  申请人：KABUSHIKI KAISHA SHOFU

  公开号：US20190300552A1

  公开（公告）日：2019-10-03

  The present invention relate to a novel silane coupling agent and a medical and/or dental curable composition comprising the same. It is an object of the present invention to provide a novel silane coupling agent that imparts high affinity to a radical polymerizable monomer, thereby imparting high mechanical strength, flexibility and durability when used for a medical and/or dental curable composition, and an inorganic filler surface-treated with the novel silane coupling agent and a novel medical and/or dental curable composition. A silane coupling agent including repeating units such as a urethane bond and polyethylene glycol (ether bond) at a specific position is used.

  本发明涉及一种新型硅烷偶联剂以及包括该偶联剂的医用和/或牙科可固化组合物。本发明的目的是提供一种新型硅烷偶联剂，使其对自由基聚合单体具有高亲和力，从而在用于医用和/或牙科可固化组合物时赋予高机械强度、柔韧性和耐久性，并且包括经新型硅烷偶联剂表面处理的无机填料和新型医用和/或牙科可固化组合物。该硅烷偶联剂包括在特定位置具有尿素键和聚乙二醇（醚键）等重复单元。
• DENTAL ADHESIVE
  申请人：KURARAY NORITAKE DENTAL INC.

  公开号：US20170196778A1

  公开（公告）日：2017-07-13

  The present invention provides a dental adhesive exhibiting excellent initial bond strength and bond durability to both enamel and dentin. The present invention relates to a dental adhesive containing: an asymmetric acrylamide-methacrylic acid ester compound (a); an acid group-containing (meth)acrylic polymerizable monomer (b); and a water-soluble polymerizable monomer (c). The asymmetric acrylamide-methacrylic acid ester compound (a) is represented by the following general formula (1): where X is an optionally substituted, linear or branched C 1 to C 6 aliphatic group or an optionally substituted aromatic group, the aliphatic group is optionally interrupted by at least one linking group selected from the group consisting of —O—, —S—, —CO—, —CO—O—, —O—CO—, —NR 1 —, —CO—NR 1 —, —NR 1 —CO—, —CO—O—NR 1 —, —O—CO—NR 1 —, and —NR 1 —CO—NR 1 —, and R 1 is a hydrogen atom or an optionally substituted, linear or branched C 1 to C 6 aliphatic group.

  本发明提供了一种牙科粘接剂，具有优异的初始粘接强度和对牙釉质和牙本质的粘接耐久性。本发明涉及一种含有以下成分的牙科粘接剂：不对称丙烯酰胺-甲基丙烯酸酯化合物（a）；含酸基的（甲基）丙烯酸聚合单体（b）；以及水溶性聚合单体（c）。不对称丙烯酰胺-甲基丙烯酸酯化合物（a）由下述一般式（1）表示：其中X是可选择取代的线性或支链状的C1到C6脂肪族基或可选择取代的芳香族基，所述脂肪族基可被来自由—O—、—S—、—CO—、—CO—O—、—O—CO—、—NR1—、—CO—NR1—、—NR1—CO—、—CO—O—NR1—、—O—CO—NR1—和—NR1—CO—NR1—组成的至少一个连接基中断，R1为氢原子或可选择取代的线性或支链状的C1到C6脂肪族基。
• [EN] DENTAL COMPOSITION<br/>[FR] COMPOSITION DENTAIRE
  申请人：DENTSPLY DETREY GMBH

  公开号：WO2018108948A1

  公开（公告）日：2018-06-21

  The present invention relates to a dental composition comprising a specific polymerizable compound and a polymerization initiator system. Furthermore, the present invention relates to the specific polymerizable compound as such and its use in a dental composition. The specific polymerizable compound of the present invention has an N-allyl (meth)acrylamide group, which nitrogen atom is substituted with an alkyl or alkenyl group optionally substituted by a group selected from a hydroxyl group, a C1-4 alkoxy group, a tertiary amino group and a carboxyl group, wherein 1 to 8 carbon atoms in the main chain of the alkyl or alkenyl group may independently from each other be replaced by a heteroatom selected from an oxygen atom and a sulfur atom.

  本发明涉及一种包括特定可聚合化合物和聚合引发剂体系的牙科组合物。此外，本发明涉及所述特定可聚合化合物本身及其在牙科组合物中的使用。本发明的特定可聚合化合物具有N-烯丙基（甲基）丙烯酰胺基团，该氮原子被烷基或烯基取代，该烷基或烯基可以选择性地被羟基、C1-4烷氧基、三级胺基和羧基中的一种取代，其中烷基或烯基中的主链的1至8个碳原子可以分别被氧原子和硫原子中选择的杂原子所取代。
• SELF-ADHESIVE DENTAL COMPOSITE RESIN
  申请人：KURARAY NORITAKE DENTAL INC.

  公开号：US20170135910A1

  公开（公告）日：2017-05-18

  The present invention provides a self-adhesive composite resin having excellent adhesiveness to tooth structures and excellent mechanical strength. The present invention relates to a self-adhesive dental composite resin containing: an asymmetric acrylamide-methacrylic acid ester compound (a); an acid group-containing (meth)acrylic polymerizable monomer (b); a hydrophobic crosslinkable polymerizable monomer (c); a photopolymerization initiator (d); and a filler (e). The asymmetric acrylamide-methacrylic acid ester compound (a) is represented by the following general formula (1): where X is an optionally substituted, linear or branched C 1 to C 6 aliphatic group or an optionally substituted aromatic group, the aliphatic group is optionally interrupted by at least one linking group selected from the group consisting of —O—, —S—, —CO—, —CO—O—, —O—CO—, —NR 1 —, —CO—NR 1 —, —NR 1 —CO—, —CO—O—NR 1 —, —O—CO—NR 1 —, and —NR 1 —CO—NR 1 —, and R 1 is a hydrogen atom or an optionally substituted, linear or branched C 1 to C 6 aliphatic group.

  本发明提供了一种具有优异粘附性和优异机械强度的自粘合复合树脂。本发明涉及一种自粘合牙科复合树脂，包含：不对称的丙烯酰胺-甲基丙烯酸酯化合物（a）；含酸基的（甲基）丙烯酸聚合单体（b）；疏水性交联聚合单体（c）；光聚合引发剂（d）；和填料（e）。不对称的丙烯酰胺-甲基丙烯酸酯化合物（a）由以下通式（1）表示：其中X是可选取代的线性或支链的C1至C6脂肪族基团或可选取代的芳香族基团，脂肪族基团可由以下组成的至少一种连接基团中断：—O—、—S—、—CO—、—CO—O—、—O—CO—、—NR1—、—CO—NR1—、—NR1—CO—、—CO—O—NR1—、—O—CO—NR1—和—NR1—CO—NR1—，R1为氢原子或可选取代的线性或支链的C1至C6脂肪族基团。
• Photo-curable reparative material for dental use
  申请人：——

  公开号：US20030162863A1

  公开（公告）日：2003-08-28

  A photocurable dental restorative comprising (i) 100 parts by weight of a polymerizable monomer, (ii) 0.01 to 5 parts by weight of a photopolymerization initiator of acylphosphine oxide, and (iii) 200 to 1900 parts by weight of an inorganic filler, wherein the inorganic filler (iii) is a mixed filler of: (A) irregular-shaped inorganic particles having an average particle size of not smaller than 0.1 &mgr;m but smaller than 1 &mgr;m; (B) spherical inorganic particles having an average primary particle size of not smaller than 0.1 &mgr;m but not larger than 5 &mgr;m; and (C) fine inorganic particles having an average primary particle size of not larger than 0.1 &mgr;m; which are so blended as to satisfy the following mass ratios circle over (1)} to circle over (3)}: mA /( mB+mC )=0.2 to 3  circle over (1)} mB /( mB+mC )=0.5 to 0.99  circle over (2)} mC /( mB+mC )=0.01 to 0.5  circle over (3)} where mA, mB and mC are masses of the inorganic particles (A) to (C). The restorative features excellent handling property, and makes it possible to obtain a cured product having a high fracture toughness and excellently glossy surface.

  一种光固化牙科修复材料，包括（i）100份重量的可聚合单体，（ii）0.01至5份重量的酰基膦氧化物光聚合引发剂，和（iii）200至1900份重量的无机填料，其中无机填料（iii）是以下混合填料：（A）具有平均粒径不小于0.1μm但小于1μm的不规则形状无机颗粒；（B）具有平均初级粒径不小于0.1μm但不大于5μm的球形无机颗粒；和（C）具有平均初级粒径不大于0.1μm的细微无机颗粒；这些颗粒混合以满足以下质量比圆圈1}至圆圈3}：mA/(mB+mC)=0.2至3；mB/(mB+mC)=0.5至0.99；mC/(mB+mC)=0.01至0.5；其中mA、mB和mC分别为无机颗粒（A）至（C）的质量。该修复材料具有出色的操作性能，可以获得具有高断裂韧性和极佳光泽表面的固化产品。