3-Hydroxy-5-phenoxypentanoic acid | 155638-20-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 3-Hydroxy-5-phenoxypentanoic acid
• CAS: 155638-20-3
• 化学式: C₁₁H₁₄O₄
• 分子量: 210.23
• InChiKey: ZKPPNJNGKKHGLI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3-Hydroxy-5-phenoxypentanoic acid 、 3-Hydroxy-7-phenoxyheptanoic acid 以is produced from 11-phenoxyundecanoic acid的产率得到11-苯氧基十一烷酸
  参考文献：
  名称：

  Polyhydroxyalkanoate containing 3-hydroxythienylalkanoic acid as monomer unit and method for producing the same

  摘要：

  具有合成新型3-羟基噻吩烷基酸单体聚羟基脂肪酸能力的微生物，使用噻吩烷基酸作为原料，在含有噻吩烷基酸的培养基上培养，提取培养细胞中产生的聚羟基脂肪酸。

  公开号：

  US20020065389A1
• 作为产物：
  描述：

  (R)-3-hydroxy-5-(4-fluorophenyl)valeryl CoA 、 (R)-3-hydroxy-5-phenoxyvaleryl CoA 反应 0.42h， 以, 250, 432-439 (1997) after obtaining 3-hydroxy-5-phenoxyvaleric acid的产率得到3-Hydroxy-5-phenoxypentanoic acid
  参考文献：
  名称：

  Particles for electrophoresis, a production method thereof and a display using the particles

  摘要：

  提供一种具有良好分散性和分散稳定性的电泳显示用电泳粒子，适用于绝缘介质，并且受到凝聚、沉淀等影响的保护，以及一种用于制备具有高适用性的颜料的电泳粒子的生产过程，以响应全彩色显示，并使用具有优异记忆性和高可靠性的电泳显示装置的电泳粒子。电泳粒子使用至少部分结构为至少部分表面覆盖有聚羟基脂肪酸酯的颜料形成。

  公开号：

  US06853477B2

文献信息

• Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same
  申请人：CANON KABUSHIKI KAISHA

  公开号：US20040067576A1

  公开（公告）日：2004-04-08

  A polyhydroxyalkanoate having a monomer unit composition represented by General Formula (1): A m B (1−m) (1) wherein A is represented by General Formula (2), B is at least one selected from the group consisting of monomer units represented by General Formula (3) or (4), and m has a value of 0.01 or larger and smaller than 1: 1 wherein n has a value of 0 to 10, k has a value of 3 or 5, and R is at least one group selected from the group consisting of groups represented by General Formulae (5) to (7): 2 in Formula (5) R1 is a group selected from the group consisting of a hydrogen atom (H), halogen atoms, —CN, —NO 2 , —CF 3 , —C 2 F 5 . and —C 3 F 7 ; and q is an integer selected from 1 to 8; in Formula (6) R2 is a group selected from the group consisting of a hydrogen atom (H), halogen atoms, —CN, —NO 2 , —CF 3 , —C 2 F 5 and —C 3 F 7 ; and r is an integer selected from 1 to 8; in Formula (7) R3 is a group selected from the group consisting of a hydrogen atom (H), halogen atoms, —CN, —NO 2 , —CF 3 , —C 2 F 5 and —C 3 F 7 ; and s is an integer selected from 1 to 8. The efficient production methods are also provided.

  一种聚羟基脂肪酸酯，其单体单元组成由通式（1）表示：AmB（1-m）（1）其中，A由通式（2）表示，B至少选自通式（3）或（4）表示的单体单元组成的群体，m的值大于或等于0.01且小于1:1。其中n的值为0到10，k的值为3或5，R至少选自通式（5）到（7）表示的群体中的一种：2在公式（5）中，R1选自氢原子（H）、卤素原子、—CN、—NO2、—CF3、—C2F5和—C3F7组成的群体，q为1到8之间的整数；在公式（6）中，R2选自氢原子（H）、卤素原子、—CN、—NO2、—CF3、—C2F5和—C3F7组成的群体，r为1到8之间的整数；在公式（7）中，R3选自氢原子（H）、卤素原子、—CN、—NO2、—CF3、—C2F5和—C3F7组成的群体，s为1到8之间的整数。同时还提供了高效的生产方法。
• Polyhydroxyalkanoates and method of producing them by utilizing mircroorganisms
  申请人：——

  公开号：US20010029039A1

  公开（公告）日：2001-10-11

  A microbial polyhydroxyalkanoate which comprises one or more of monomer units represented by Formula (1), 1 where R is at least one selected from the group represented by any one of Formulas (2), (3) and (4); 2 in Formula (2), R1 is selected from the group consisting of hydrogen atom (H), halogen atom, —CN, —NO 2 , —CF 3 , —C 2 F 5 and —C 3 F 7 , and q is an integer of 1 to 8; in Formula (3), R2 is selected from the group consisting of hydrogen atom (H), halogen atom, —CN, —NO 2 , —CF 3 , —C 2 F 5 and —C 3 F 7 , and r is an integer of 1 to 8; in Formula (4), R3 is selected from the group consisting of hydrogen atom (H), halogen atom, —CN, —NO 2 , —CF 3 , —C 2 F 5 and —C 3 F 7 , and s is an integer of 1 to 8. The production method is also disclosed.

  一种微生物聚羟基烷酸酯，包括由式（1）表示的单体单元中的一个或多个，其中R至少选自式（2）、（3）和（4）所表示的任一组中的一种；在式（2）中，R1选自氢原子（H）、卤素原子、—CN、—NO2、—CF3、—C2F5和—C3F7组成的一组中，q是1到8的整数；在式（3）中，R2选自氢原子（H）、卤素原子、—CN、—NO2、—CF3、—C2F5和—C3F7组成的一组中，r是1到8的整数；在式（4）中，R3选自氢原子（H）、卤素原子、—CN、—NO2、—CF3、—C2F5和—C3F7组成的一组中，s是1到8的整数。同时公开了生产方法。
• Process for producing polyhydroxyalkanoates by utilizing microorganisms
  申请人：——

  公开号：US20030180899A1

  公开（公告）日：2003-09-25

  A microbial polyhydroxyalkanoate which comprises one or more of monomer units represented by Formula (1), 1 where R is at least one selected from the group represented by any one of Formulas (2), (3) and (4); 2 in Formula (2), R1 is selected from the group consisting of hydrogen atom (H), halogen atom, —CN, —NO 2 , —CF 3 , —C 2 F 5 and —C 3 F 7 , and q is an integer of 1 to 8; in Formula (3), R2 is selected from the group consisting of hydrogen atom (H), halogen atom, —CN, —NO 2 , —CF 3 , —C 2 F 5 and —C 3 F 7 , and r is an integer of 1 to 8; in Formula (4), R3 is selected from the group consisting of hydrogen atom (H), halogen atom, —CN, —NO 2 , —CF 3 , —C 2 F 5 and —C 3 F 7 , and s is an integer of 1 to 8. The production method is also disclosed.

  一种微生物聚羟基脂肪酸酯，包括由公式（1）表示的单体单元中的一个或多个，其中R至少选自任一公式（2）、（3）和（4）所表示的组中之一；在公式（2）中，R1从氢原子（H）、卤素原子、—CN、—NO2、—CF3、—C2F5和—C3F7组成的组中选择，q为1至8的整数；在公式（3）中，R2从氢原子（H）、卤素原子、—CN、—NO2、—CF3、—C2F5和—C3F7组成的组中选择，r为1至8的整数；在公式（4）中，R3从氢原子（H）、卤素原子、—CN、—NO2、—CF3、—C2F5和—C3F7组成的组中选择，s为1至8的整数。还公开了生产方法。
• Particulate construct comprising polyhydroxyalkanoate and method for producing it
  申请人：——

  公开号：US20030194443A1

  公开（公告）日：2003-10-16

  The invention provides a particulate construct such as microcapsules containing a drug, and serving a slow releasing preparation not associated with a practically unacceptable initial burst release but showing a practically acceptable zero-order release for a certain period and a producing method for such particulate construct, and a slow releasing preparation of a high drug content capable of stably incorporating the drug in the particulate construct such as microcapsules, and a producing method for such preparation. The invention also provides a particulate construct such as microcapsules utilizing a highly functional polymer compound and incorporating oil phase and/or water phase in solid phase, and a producing method therefor. Furthermore, the invention provides a particulate construct such as microcapsules having a hollow structure of a single polymer membrane as the outer shell and capable of containing many bubbles in the fine particles, and a producing method capable of preparing such construct with a high reproducibility. According to the invention, a particulate construct such as microcapsules is formed with polyhydroxyalkanoate of a specified structure and a drug for a desired purpose, an oil phase and/or a water phase, or a gaseous phase is included in such construct.

  本发明提供了一种微粒构造物，例如包含药物的微胶囊，用作缓释制剂，不会出现实际上不可接受的初始爆发释放，但在一定时间内显示实际上可接受的零级释放，并提供了这种微粒构造物的制备方法，以及能够稳定地将药物纳入微粒构造物中，例如微胶囊的高药物含量的缓释制剂，以及这种制备方法。本发明还提供了一种利用高功能聚合物化合物并将油相和/或水相纳入固相的微粒构造物，以及其制备方法。此外，本发明还提供了一种具有单一聚合物膜的空心结构的微粒构造物，能够在细小的颗粒中包含许多气泡，并提供了一种能够高度重复制备这种构造物的制备方法。根据本发明，可使用具有特定结构的聚羟基烷酸酯和药物制备微粒构造物，该构造物中包含油相和/或水相或气态相。
• Pigment containing ink and production method thereof
  申请人：——

  公开号：US20030203987A1

  公开（公告）日：2003-10-30

  A micro-capsulated pigment containing pigment ink being excellent in density, fineness, transparency, and coloring and color rendering properties required for ink solutions and having excellent dispersibility and dispersion stability with time due to the reduced particle size is provided. At least a color material with at least part of the surfaces of pigment particles covered with polyhydroxyalkanoate, and a medium for dispersion of the color material are used to obtain the pigment ink.

  提供了一种微胶囊化颜料，其中包含颜料油墨，其具有油墨溶液所需的密度、细度、透明度、着色和色彩还原性，由于粒子尺寸的减小，具有优异的分散性和稳定性。使用至少一种颜料材料，其中颜料颗粒的至少一部分表面被聚羟基脂肪酸酯覆盖，以及用于分散颜料材料的介质来获得颜料油墨。