9-Oxononyl methanesulfonate | 1246855-64-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: 9-Oxononyl methanesulfonate
• CAS: 1246855-64-0
• 化学式: C₁₀H₂₀O₄S
• 分子量: 236.332
• InChiKey: UBBMYLYZADBJBB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  15
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  68.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  9-Oxononyl methanesulfonate 在 锰 、 水 、 2,4,6-collidine hydrochloride 作用下， 以 四氢呋喃 为溶剂， 以83%的产率得到C₁₀H₂₂O₄S
  参考文献：
  名称：

  Mn(0)-Mediated Chemoselective Reduction of Aldehydes. Application to the Synthesis of α-Deuterioalcohols

  摘要：

  A mild simple safe chemoselective reduction of different kinds to the corresponding alcohols mediated by the Mn dust/water system is described. In addition to this, the use of D2O leads to the synthesis of alpha-deuerated alcohols and constitutes an efficient inexpensive alternative for the preparation of these compounds.

  DOI：

  10.1021/jo1015618
• 作为产物：
  描述：

  C₁₀H₂₂O₄S 在 戴斯-马丁氧化剂 作用下， 以 二氯甲烷 为溶剂， 以70%的产率得到9-Oxononyl methanesulfonate
  参考文献：
  名称：

  Mn(0)-Mediated Chemoselective Reduction of Aldehydes. Application to the Synthesis of α-Deuterioalcohols

  摘要：

  A mild simple safe chemoselective reduction of different kinds to the corresponding alcohols mediated by the Mn dust/water system is described. In addition to this, the use of D2O leads to the synthesis of alpha-deuerated alcohols and constitutes an efficient inexpensive alternative for the preparation of these compounds.

  DOI：

  10.1021/jo1015618

文献信息

• Dehydrogenative Synthesis of Linear α,β-Unsaturated Aldehydes with Oxygen at Room Temperature Enabled by ^<i>t</i>BuONO
  作者：Mei-Mei Wang、Xiao-Shan Ning、Jian-Ping Qu、Yan-Biao Kang

  DOI：10.1021/acscatal.7b01008

  日期：2017.6.2

  Synthesis of linear α,β-unsaturated aldehydes via a room-temperature oxidative dehydrogenation has been realized by the cocatalysis of an organic nitrite and palladium with molecular oxygen as the sole clean oxidant. Linear α,β-unsaturated aldehydes could be efficiently prepared under aerobic catalytic conditions directly from the corresponding saturated linear aldehydes. Besides linear products, the

  通过有机亚硝酸盐和钯与分子氧作为唯一的清洁氧化剂的共催化，已经实现了通过室温氧化脱氢合成线性α，β-不饱和醛。线性α，β-不饱和醛可以在需氧催化条件下直接由相应的饱和线性醛有效地制备。除线性产品外，通过相同的标准方法也可以顺利实现芳香族类比。有机亚硝酸盐氧化还原助催化剂和醇溶剂在实现该方法中起着关键作用。
• Process for preparing functional group-containing olefinic compounds
  申请人：3M Innovative Properties Company

  公开号：EP2314559A2

  公开（公告）日：2011-04-27

  A process for preparing functional group-containing olefinic compounds comprising the steps of (a) reacting (1) at least one functional group-containing nucleophile with (2) at least one carbonyl-containing compound that comprises at least one group that is a leaving group, or that is capable of subsequent conversion to a leaving group, and that optionally comprises one or more isolated carbon to carbon double or triple bonds, to form the corresponding functional group-containing carbonyl-containing compound, said carbonyl-containing compound being selected from the group consisting of ketones and aldehydes; and (b) reacting said functional group-containing carbonyl-containing compound with at least one alkylidene phosphorane comprising an alkylidene moiety and three other moieties bonded to its phosphorus atom, said alkylidene moiety optionally comprising one or more carbon to carbon double or triple bonds, to form a functional group-containing olefinic compound.

  一种制备含官能团烯烃化合物的工艺，包括以下步骤 (a) 使(1)至少一种含官能团的亲核体与(2)至少一种含羰基的化合物反应，该化合物包含至少一个离去基团或可随后转化为离去基团的基团，并可选择包含一个或多个孤立的碳对碳双键或三键，以形成相应的含官能团的含羰基的化合物，所述含羰基的化合物选自由酮和醛组成的组；(b) 使所述含官能团的羰基化合物与至少一种亚烷基磷烷反应，所述亚烷基磷烷包括一个亚烷基分子和与磷原子成键的另外三个分子，所述亚烷基分子可选择包括一个或多个碳对碳双键或三键，以形成含官能团的烯烃化合物。
• PROCESS FOR PREPARING FUNCTIONAL GROUP-CONTAINING OLEFINIC COMPOUNDS
  申请人：3M Innovative Properties Company

  公开号：EP1678115A2

  公开（公告）日：2006-07-12
• Prosthetic Valve with Sealing Members and Methods of Use Thereof
  申请人：Tabor Charles

  公开号：US20110264206A1

  公开（公告）日：2011-10-27

  Embodiments of the present invention provide prosthetic valves having sealing members on the external surface thereof. The prosthetic heart valves of the present invention are preferably delivered by catheter directly through the apex of the heart or by other close range transcatheter delivery methods. Because these methods of implantation require a shorter length of catheter, a prosthetic valve can be more accurately oriented in the desired implantation location. Fluoroscopy can be used to further assist in orientation of the valve. The sealing members of the present invention can be positioned on the prosthetic valve such that, when the prosthetic valve is implanted in a native annulus, each provided sealing member is located adjacent to a commissural point of the native valve leaflets. Because the sealing members are precisely oriented on the prosthetic valve, a physician can ensure that the sealing members are aligned with the commissural points of the native valve leaflets. In embodiments of the present invention, the prosthetic valve can have a waisted middle section, and the sealing members can be located in the waisted middle section such that the crimped diameter of the prosthetic valve is not negatively impacted by the sealing members.
• US6838576B1
  申请人：——

  公开号：US6838576B1

  公开（公告）日：2005-01-04