[4-(2-咪唑-1-基乙氧基)苯基]甲醇 | 100199-60-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 中文名称: [4-(2-咪唑-1-基乙氧基)苯基]甲醇
• 英文名称: Benzenemethanol, 4-(2-(1H-imidazol-1-yl)ethoxy)-
• 英文别名: [4-(2-imidazol-1-ylethoxy)phenyl]methanol
• CAS: 100199-60-8
• 化学式: C₁₂H₁₄N₂O₂
• mdl: MFCD01761957
• 分子量: 218.255
• InChiKey: GDNYXDJGFLTMJN-UHFFFAOYSA-N

物化性质

• 沸点：
  462.9±30.0 °C(Predicted)
• 密度：
  1.16±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  47.3
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  [4-(2-咪唑-1-基乙氧基)苯基]甲醇 在 ammonium tetrafluoroborate 、 N,N-二异丙基乙胺 作用下， 以 二氯甲烷 、 乙腈 为溶剂， 反应 68.0h， 生成
  参考文献：
  名称：

  Synthesis and preliminary use of novel acrylic ester-derived task-specific ionic liquids

  摘要：

  Novel electrophilic alkenes bearing an ionic liquid-type appendage have been prepared and used in Diels-Alder cycloadditions, 1,4-additions, Heck couplings and Stetter reactions; this new type Of Support allows easy monitoring of the reactions by NMR and MS as well as simple and efficient work-up and isolation procedures. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2003.10.198
• 作为产物：
  描述：

  methyl 4-<2-(1H-imidazol-1-yl)-ethoxy>-benzoate 在 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 为溶剂， 反应 17.0h， 以88%的产率得到[4-(2-咪唑-1-基乙氧基)苯基]甲醇
  参考文献：
  名称：

  Synthesis and preliminary use of novel acrylic ester-derived task-specific ionic liquids

  摘要：

  Novel electrophilic alkenes bearing an ionic liquid-type appendage have been prepared and used in Diels-Alder cycloadditions, 1,4-additions, Heck couplings and Stetter reactions; this new type Of Support allows easy monitoring of the reactions by NMR and MS as well as simple and efficient work-up and isolation procedures. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2003.10.198

文献信息

• BRUNO, G.;CAHN, J.
  作者：BRUNO, G.、CAHN, J.

  DOI：——

  日期：——
• Synthesis and preliminary use of novel acrylic ester-derived task-specific ionic liquids
  作者：Siddam Anjaiah、Srivari Chandrasekhar、René Grée

  DOI：10.1016/j.tetlet.2003.10.198

  日期：2004.1

  Novel electrophilic alkenes bearing an ionic liquid-type appendage have been prepared and used in Diels-Alder cycloadditions, 1,4-additions, Heck couplings and Stetter reactions; this new type Of Support allows easy monitoring of the reactions by NMR and MS as well as simple and efficient work-up and isolation procedures. (C) 2003 Elsevier Ltd. All rights reserved.