Propylene glycol 2-caprate | 170678-32-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Propylene glycol 2-caprate
• 英文别名: 1-hydroxypropan-2-yl decanoate
• CAS: 170678-32-7
• 化学式: C₁₃H₂₆O₃
• 分子量: 230.34
• InChiKey: PKEJCCNSYCBFJE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  16
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Cosmetic composition and production thereof
  申请人：Kawasaki Yuji

  公开号：US20060018867A1

  公开（公告）日：2006-01-26

  It has been desired to develop a highly preservative and antibacterial cosmetic composition that can easily be applied to both emulsion and non-emulsion type cosmetics. It has also been desired to develop a method of improving a preservative and/or antibacterial effect(s) of a cosmetic composition comprising polyorganosiloxane-containing epsilon-polylysine and thereby reducing the amount of antibacterial preservative agent to be used. There is provided a cosmetic composition comprising one or a combination of two or more of polyorganosiloxane-containing epsilon-polylysine compounds obtained by reacting epsilon-polylysine with polyorganosiloxane or a physiologically acceptable salt thereof, and polyhydric alcohol.

  人们一直希望开发一种高防腐性和抗菌性的化妆品组合物，这种组合物既可用于乳液型化妆品，也可用于非乳液型化妆品。此外，还希望开发一种方法，以改善含有聚有机硅氧烷的ε-聚赖氨酸的化妆品组合物的防腐和/或抗菌效果，从而减少抗菌防腐剂的用量。本发明提供了一种化妆品组合物，该组合物包含一种或两种以上的含聚有机硅氧烷的ε-聚赖氨酸化合物的组合，这些ε-聚赖氨酸化合物是通过ε-聚赖氨酸与聚有机硅氧烷或其生理上可接受的盐以及多元醇反应而得到的。
• Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof
  申请人：Chisso Corporation

  公开号：EP1604647B1

  公开（公告）日：2008-05-07
• PHARMACEUTICAL COMPOSITIONS OF 5-HYDROXY-2-METHYLNAPHTHALENE-1, 4-DIONE
  申请人：Pellficure Pharmaceuticals, Inc.

  公开号：EP3528799A1

  公开（公告）日：2019-08-28
• PHARMACEUTICAL COMPOSITIONS OF 5-HYDROXY-2-METHYLNAPHTHALENE-1,4-DIONE
  申请人：PellFiCure Pharmaceuticals, Inc.

  公开号：US20180221306A1

  公开（公告）日：2018-08-09

  Disclosed herein are pharmaceutical compositions of 5-hydroxy-2-methylnaphthalene-1,4-dione. Also disclosed are methods of treating diseases and/or conditions associated with a cancer, such as prostate cancer with such pharmaceutical compositions of 5-hydroxy-2-methylnaphthalene-1,4-dione. The disclosed pharmaceutical compositions may provide improved dosage for oral administration to patients in the clinic. The disclosed pharmaceutical compositions may provide improved stability and/or shelf life.
• [EN] PHARMACEUTICAL COMPOSITIONS OF 5-HYDROXY-2-METHYLNAPHTHALENE-1, 4-DIONE<br/>[FR] COMPOSITIONS PHARMACEUTIQUES DE 5-HYDROXY-2-MÉTHYLNAPHTALÈNE-1, 4-DIONE
  申请人：PELLFICURE PHARMACEUTICALS INC

  公开号：WO2018080933A1

  公开（公告）日：2018-05-03

  Disclosed herein are pharmaceutical compositions of 5-hydroxy-2- methylnaphthalene-l,4-dione. Also disclosed are methods of treating diseases and/or conditions associated with a cancer, such as prostate cancer with such pharmaceutical compositions of 5-hydroxy-2-methylnaphthalene-l,4-dione. The disclosed pharmaceutical compositions may provide improved dosage for oral administration to patients in the clinic. The disclosed pharmaceutical compositions may provide improved stability and/or shelf life.