2-Butyl-2-(propan-2-yl)propane-1,3-diol | 299171-88-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-Butyl-2-(propan-2-yl)propane-1,3-diol
• 英文别名: 2-butyl-2-propan-2-ylpropane-1,3-diol
• CAS: 299171-88-3
• 化学式: C₁₀H₂₂O₂
• 分子量: 174.28
• InChiKey: AQHPICNWFNXTGE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Heterocyclic Ring and Carbocyclic Derivative
  申请人：Shionogi & Co., Ltd.

  公开号：US20160024072A1

  公开（公告）日：2016-01-28

  The present invention provides novel compounds having a P2X 3 and/or P2X 2/3 receptor antagonistic effect, e.g. a compound of Formula (I): wherein R 2 is a hydrogen atom or the like; ring A is five- to seven-cycloalkane or the like; C is a carbon atom; Q 1 and Q 2 are carbon atoms or the like; R 9a and R 9b are carbon atoms or the like; R 6 is cycloalkyl or the like; R 7 is a group represented by the formula: wherein ring D is benzene or the like; carbon atom a and b are carbon atoms; ring B is an aromatic carbocyclic ring or the like; s and s′ are 0 or the like; R 9 and R 9′ are halogen or the like, or the like, or its pharmaceutically acceptable salt.

  本发明提供了具有P2X3和/或P2X2/3受体拮抗作用的新化合物，例如Formula (I)的化合物：其中R2是氢原子或类似物；环A是五至七环烷或类似物；C是碳原子；Q1和Q2是碳原子或类似物；R9a和R9b是碳原子或类似物；R6是环烷基或类似物；R7是由以下公式表示的基团：其中环D是苯或类似物；碳原子a和b是碳原子；环B是芳香族碳环或类似物；s和s'为0或类似物；R9和R9'是卤素或类似物，或其药用可接受盐。
• Antiseptic/antifungal agent and endermic liniment composition which contains it
  申请人：SHISEIDO COMPANY LIMITED

  公开号：EP1040757A1

  公开（公告）日：2000-10-04

  The present invention is an antiseptic/antifungal agent in which 2, 2-dialkyl-1,3-propanediol represented by the following general formula (I) is an effective component: [In this formula, R1 and R2 can either be identical or different from each other, and both denote an alkyl group with a carbon number of 1 - 4. ] as well as an endermic liniment composition which contains it. The present invention is also an endermic liniment composition which contains 3-methyl-3-methoxybutanol and 1,2-pentane diol, as well as an endermic liniment composition which contains 3-methyl-3-methoxybutanol and 2-phenoxy ethanol. The endermic liniment composition of the present invention contains an antiseptic/antifungal agent with much superior safety and usability and is used for cosmetics and such.

  本发明是一种防腐剂/抗真菌剂，其中由以下通式（I）代表的 2，2-二烷基-1，3-丙二醇是一种有效成分： [式中，R1 和 R2 既可以相同，也可以不同，均表示碳数为 1 - 4 的烷基。] 以及含有该成分的皮肤护理剂组合物。本发明也是一种含有 3-甲基-3-甲氧基丁醇和 1,2-戊二醇的皮肤护理剂组合物，以及一种含有 3-甲基-3-甲氧基丁醇和 2-苯氧基乙醇的皮肤护理剂组合物。 本发明的皮肤护理剂组合物含有一种防腐剂/抗真菌剂，其安全性和实用性大大提高，可用于化妆品等。
• PROPYLENE POLYMER, METHOD FOR PRODUCTION OF THE PROPYLENE POLYMER, PROPYLENE POLYMER COMPOSITION, AND MOLDED ARTICLE MANUFACTURED FROM THE COMPOSITION
  申请人：Japan Polypropylene Corporation

  公开号：EP1980576A1

  公开（公告）日：2008-10-15

  Disclosed is a production method of polypropylene having high MFR value and excellent product qualities with high productivity. The method enables to produce a propylene polymer by a gas phase process where the reaction heat is removed mainly by the heat of vaporization of liquefied propylene. The method is characterized by using a solid catalyst component (A) which is prepared by contacting components (A1), (A2) and (A3) shown below. Further disclosed are: a propylene polymer produced by the method; a propylene polymer composition; and a molded body of the composition. Component (A1) : a solid component containing titanium, magnesium and a halogen as essential components. Component (A2): a vinyl silane compound. Component (A3): an organosilicon compound having an alkoxy group (A3a) and/or a compound having at least two ether bonds (A3b).

  本发明公开了一种生产聚丙烯的方法，该方法具有较高的 MFR 值和优异的产品质量，且生产率高。该方法可通过气相工艺生产丙烯聚合物，在气相工艺中，反应热主要通过液化丙烯的汽化热带走。该方法的特点是使用固体催化剂组分 (A)，该组分是由下图所示的组分 (A1)、(A2) 和 (A3) 接触制备的。进一步公开了：用该方法生产的丙烯聚合物；丙烯聚合物组合物；以及该组合物的模塑体。组分 (A1)：一种固体组分，其主要成分为钛、镁和卤素。组分（A2）：乙烯基硅烷化合物。组分（A3）：具有一个烷氧基（A3a）和/或至少具有两个醚键（A3b）的有机硅化合物。
• PROPYLENE-BASED POLYMER AND PRODUCTION METHOD THEREFOR, PROPYLENE-BASED POLYMER COMPOSITION AND MOLDED BODY MADE THEREOF
  申请人：KOBAYASHI Yoshitaka

  公开号：US20100099811A1

  公开（公告）日：2010-04-22

  Disclosed is a production method of polypropylene having high MFR value and excellent product qualities with high productivity. The method enables to produce a propylene polymer by a gas phase process where the reaction heat is removed mainly by the heat of vaporization of liquefied propylene. The method is characterized by using a solid catalyst component (A) which is prepared by contacting components (A1), (A2) and (A3) shown below. Further disclosed are: a propylene polymer produced by the method; a propylene polymer composition; and a molded body of the composition. Component (A1): a solid component containing titanium, magnesium and a halogen as essential components. Component (A2): a vinyl silane compound. Component (A3): an organosilicon compound having an alkoxy group (A3 a ) and/or a compound having at least two ether bonds (A3 b ).
• US6620418B1
  申请人：——

  公开号：US6620418B1

  公开（公告）日：2003-09-16