Propyl 4-bromo-3-hydroxybutanoate | 828276-58-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羟基酸及其衍生物
• 英文名称: Propyl 4-bromo-3-hydroxybutanoate
• CAS: 828276-58-0
• 化学式: C₇H₁₃BrO₃
• 分子量: 225.08
• InChiKey: CAWAXRYLKWINSI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• PROCESS FOR PRODUCING BUTYRIC ESTER DERIVATIVES
  申请人：KANEKA CORPORATION

  公开号：EP0970947A1

  公开（公告）日：2000-01-12

  This invention has its objects to provide a process for producing a butyric acid ester derivative of the above general formula (2) which is capable of removing various impurity byproducts whose formation cannot be avoided by the prior art technology, particularly the compound of the above general formula (1), with good efficiency. This invention is related to a process for producing a butyric acid ester derivative of the general formula (2) which comprises treating a mixture containing a compound of the following general formula (1) with an addition reagent capable of adding itself to said ethylenic bond to thereby convert said compound of the general formula (1) to an addition product which can be easily separated from said butyric acid ester derivative of the general formula (2) and a process for producing a butyric acid ester derivative of the general formula (2) which comprises reacting a compound of the general formula (3) with a salt of prussic acid by a flow method.         HOCH2-CH=CH-COOR     (1)

  本发明的目的是提供一种生产上述通式(2)的丁酸酯衍生物的工艺，该工艺能够以良好的效率去除现有技术无法避免形成的各种杂质副产物，特别是上述通式(1)的化合物。 本发明涉及一种生产通式(2)丁酸酯衍生物的工艺，该工艺包括用一种加成试剂处理含有下 述通式(1)化合物的混合物，该加成试剂能将自身加到所述乙烯键上，从而将所述通式(1) 化合物转化为加成产物。通式(2)丁酸酯衍生物的生产工艺，包括通过流动法使通式(3)化合物与普鲁士酸盐反应。 HOCH2-CH=CH-COOR (1)
• EP0970947B1
  申请人：——

  公开号：EP0970947B1

  公开（公告）日：2005-01-26
• US6140527A
  申请人：——

  公开号：US6140527A

  公开（公告）日：2000-10-31