[6]-姜二醇3,5-二乙酸酯 | 143615-75-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: [6]-姜二醇3,5-二乙酸酯
• 中文别名: 二乙酰氧基-6-姜二醇
• 英文名称: [6]-Gingerdiol 3,5-diacetate
• 英文别名: [3-acetyloxy-1-(4-hydroxy-3-methoxyphenyl)decan-5-yl] acetate
• CAS: 143615-75-2
• 化学式: C₂₁H₃₂O₆
• 分子量: 380.5
• InChiKey: PXBFKEHWQRAQQD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  27
• 可旋转键数：
  14
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  82.1
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• [EN] GINGEROL COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS<br/>[FR] COMPOSÉS DE GINGÉROL ET LEUR UTILISATION EN TANT QUE MODIFICATEURS D'ARÔME
  申请人：FIRMENICH & CIE

  公开号：WO2021094268A1

  公开（公告）日：2021-05-20

  The present disclosure relates to gingerol compounds, whether in their diol form or as a derivative, and their use to enhance the salty taste or the umami taste of a flavored article. The disclosure also provides compositions and flavored products containing such compounds. In some embodiments, the flavored products have reduced amounts of salt or umami-enhancing compounds (glutamates, arginates, purinic ribonucleotides, such as inosine monophosphate (IMP) and guanosine monophosphate (GMP)), relative to comparable flavored products that do not incorporate the gingerol compounds. The disclosure further provides methods of making monoacetate or diacetate derivatives of gingerol diols.

  本公开涉及姜酚化合物，无论是以它们的二醇形式还是作为衍生物，并且它们的用途是增强调味品的咸味或鲜味。该公开还提供了含有这些化合物的组合物和调味产品。在某些实施例中，相对于不含姜酚化合物的类似调味产品，这些调味产品的盐或鲜味增强化合物（谷氨酸盐、精氨酸盐、嘌呤核苷酸盐，例如肌苷酸酸（IMP）和鸟苷酸酸（GMP））的含量减少。该公开还提供制备姜酚二醇的单醋酸酯或双醋酸酯衍生物的方法。
• REDUCED SODIUM FOOD PRODUCTS
  申请人：GENERAL MILLS, INC.

  公开号：EP2954037B1

  公开（公告）日：2018-04-11
• Ginger Extract For Inhibiting Human Drug Transporters
  申请人：Ishiguro Naoki

  公开号：US20090011059A1

  公开（公告）日：2009-01-08

  The present invention relates to the use of a ginger extract on its own or in combination with pharmaceutical compositions for inhibiting human drug transporters for positively influencing the oral bioavailability and pharmacokinetics of active substances.
• [EN] GINGER EXTRACT FOR INHIBITING HUMAN DRUG TRANSPORTERS<br/>[FR] EXTRAIT DE GINGEMBRE POUR INHIBER DES TRANSPORTEURS DE MEDICAMENT HUMAINS
  申请人：BOEHRINGER INGELHEIM INT

  公开号：WO2007071721A2

  公开（公告）日：2007-06-28

  [EN] The present invention relates to the use of a ginger extract on its own or in combination with pharmaceutical compositions for inhibiting human drug transporters for positively influencing the oral bioavailability and pharmacokinetics of active substances.
  [FR] La présente invention concerne l'utilisation d'un extrait de gingembre seul ou en combinaison avec des compositions pharmaceutiques pour inhiber des transporteurs de médicament humains pour influencer positivement la biodisponibilité et la pharmacocinétique orales de substances actives.