1-<4-Hydroxy-3-methoxy-phenyl>-hexan-3-on | 53172-00-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 1-<4-Hydroxy-3-methoxy-phenyl>-hexan-3-on
• 英文别名: (2)-Paradol；<2>-Paradol；1-(4-hydroxy-3-methoxy-phenyl)-hexan-3-one；1-(4-Hydroxy-3-methoxy-phenyl)-hexan-3-on；1-(4-Hydroxy-3-methoxyphenyl)hexan-3-one
• CAS: 53172-00-2
• 化学式: C₁₃H₁₈O₃
• 分子量: 222.284
• InChiKey: TWKXRMWIRZAHEI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  香草醛 在 palladium on activated charcoal 四氢吡咯 、 氢气 、 溶剂黄146 作用下， 生成 1-<4-Hydroxy-3-methoxy-phenyl>-hexan-3-on
  参考文献：
  名称：

  辛辣的化合物。第一部分。改进的对位异构体（烷基4-羟基-3-甲氧基苯乙基酮）的合成及其辛辣度评估

  摘要：

  同源系列的11个对位的多巴酚，其中一个[6]对位的多酚（正庚基4-羟基-3-甲氧基苯乙基酮）天然存在于砂仁砂仁（Zingiberaceae）的种子中（也称为天堂谷物） ，几内亚胡椒或Melegueta胡椒）已通过一种改良方法合成。该系列介绍了包括g​​lc行为在内的物理特性和刺激性评估实验。

  DOI：

  10.1039/p19720003001

文献信息

• Inhibitors Of Cognitive Decline
  申请人：Rishton Gilbert M.

  公开号：US20080193574A1

  公开（公告）日：2008-08-14

  Compounds that are central nervous system drug candidates for the treatment of cognitive decline and, more particularly, Alzheimer's disease are provided. Methods of treating, inhibiting, and/or abatement of cognitive decline and Alzheimer's disease with a derivative of ginger oil are also provided. Also provided is a method of conditioning biological extracts, such as a medicinal plant extract, by a reductive amination process to give nitrogen-containing derivatives.
• Inhibitors of cognitive decline
  申请人：Rishton Gilbert M.

  公开号：US20110111068A1

  公开（公告）日：2011-05-12

  Compounds that are central nervous system drug candidates for the treatment of cognitive decline and, more particularly, Alzheimer's disease are provided. Methods of treating, inhibiting, and/or abatement of cognitive decline and Alzheimer's disease with a derivative of ginger oil are also provided. Also provided is a method of conditioning biological extracts, such as a medicinal plant extract, by a reductive amination process to give nitrogen-containing derivatives.
• US7723377B2
  申请人：——

  公开号：US7723377B2

  公开（公告）日：2010-05-25
• Nomura; Hotta, Science Reports of the Tohoku University, Series 1: Physics, Chemistry, Astronomy, vol. 14, p. 136
  作者：Nomura、Hotta

  DOI：——

  日期：——