p-coumaroyl aspartate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: p-coumaroyl aspartate
• 英文别名: n-[4'-Hydroxy-(e)-cinnamoyl]-l-aspartic acid；2-[[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]amino]butanedioic acid
• 化学式: C₁₃H₁₃NO₆
• 分子量: 279.249
• InChiKey: FKBRNPNAUOXZMQ-ZZXKWVIFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  20
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  124
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  对羟基肉桂酸 、 (S)-Di-tert-butyl 2-aminosuccinate hydrochloride 在 1-羟基苯并三唑 、 N,N-二异丙基乙胺 、 三氟乙酸 、 N,N'-二异丙基碳二亚胺 作用下， 生成 p-coumaroyl aspartate
  参考文献：
  名称：

  Coumaroylaspartate from cell suspension cultures of Arabidopsis thaliana

  摘要：

  A major new compound was isolated from cell suspension cultures of Arabidopsis thaliana and its structure shown to be N-(E-4-coumaroyl)-aspartate by ion spray MS and MS/MS as well as H-1 NMR spectroscopy. This amide was chemically synthesized and found to be identical with the natural isolate.

  DOI：

  10.1016/s0031-9422(00)90798-2

文献信息

• Extract of undifferentiated cells of Mimosa pudica and uses thereof in dermo-cosmetics
  申请人：PIERRE FABRE DERMO-COSMETIQUE

  公开号：US10954488B2

  公开（公告）日：2021-03-23

  The present invention relates to a preparation obtained from an in vitro culture of undifferentiated cells of Mimosa pudica, as well as to the preparation method thereof; a cosmetic or dermatological composition comprising said preparation; and the uses thereof for the treatment of inflammatory skin conditions, as an antioxidant agent in the treatment of oxidative stress caused by environmental pollution, and as an anti-aging agent.

  本发明涉及一种从含羞草未分化细胞体外培养中获得的制剂及其制备方法；一种包含上述制剂的化妆品或皮肤科组合物；以及其在治疗炎症性皮肤病、作为抗氧化剂治疗环境污染引起的氧化应激和作为抗衰老剂方面的用途。
• EXTRAIT DE CELLULES INDIFFERENCIEES DE MIMOSA PUDICA ET SES UTILISATIONS EN DERMO-COSMETIQUE
  申请人：Pierre Fabre Dermo-Cosmétique

  公开号：EP3471837A2

  公开（公告）日：2019-04-24
• EXTRACT OF UNDIFFERENTIATED CELLS OF MIMOSA PUDICA AND USES THEREOF IN DERMO-COSMETICS
  申请人：PIERRE FABRE DERMO-COSMETIQUE

  公开号：US20190136181A1

  公开（公告）日：2019-05-09

  The present invention relates to a preparation obtained from an in vitro culture of undifferentiated cells of Mimosa pudica , as well as to the preparation method thereof; a cosmetic or dermatological composition comprising said preparation; and the uses thereof for the treatment of inflammatory skin conditions, as an antioxidant agent in the treatment of oxidative stress caused by environmental pollution, and as an anti-aging agent.
• [EN] EXTRACT OF UNDIFFERENTIATED CELLS OF MIMOSA PUDICA AND USES THEREOF IN DERMO-COSMETICS<br/>[FR] EXTRAIT DE CELLULES INDIFFERENCIEES DE MIMOSA PUDICA ET SES UTILISATIONS EN DERMO-COSMETIQUE
  申请人：PIERRE FABRE DERMO-COSMETIQUE

  公开号：WO2017216274A2

  公开（公告）日：2017-12-21

  La présente invention concerne une préparation issue d'une culture in vitro de cellules indifférenciées de Mimosa pudica ainsi que son procédé de préparation; une composition cosmétique ou dermatologique comprenant ladite préparation; et ses utilisations pour le traitement des troubles inflammatoires cutanés, comme agent anti-oxydant dont le traitement des stress oxydatifs dus à la pollution environnementale, et comme agent anti-âge
• Coumaroylaspartate from cell suspension cultures of Arabidopsis thaliana
  作者：Hans-Peter Mock、Victor Wray、Werner Beck、Jörg W. Metzger、Dieter Strack

  DOI：10.1016/s0031-9422(00)90798-2

  日期：1993.8

  A major new compound was isolated from cell suspension cultures of Arabidopsis thaliana and its structure shown to be N-(E-4-coumaroyl)-aspartate by ion spray MS and MS/MS as well as H-1 NMR spectroscopy. This amide was chemically synthesized and found to be identical with the natural isolate.