Methanone, (2-iodo-5-nitrophenyl)(1-(((2R)-1-methyl-2-piperidinyl)methyl)-1H-indol-3-yl)- | 444912-51-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: Methanone, (2-iodo-5-nitrophenyl)(1-(((2R)-1-methyl-2-piperidinyl)methyl)-1H-indol-3-yl)-
• 英文别名: (2-iodo-5-nitrophenyl)-[1-[[(2R)-1-methylpiperidin-2-yl]methyl]indol-3-yl]methanone
• CAS: 444912-51-0
• 化学式: C22H22IN3O3
• 分子量: 503.3
• InChiKey: ZUHIXXCLLBMBDW-MRXNPFEDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  29
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  71.1
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Use of heme oxygenase 1 inducers and cannabinoid 2 receptor or delta-opioid receptor agonists in inflammatory pain
  申请人：Fundació Institut de Recerca de l'Hospital de la Santa Creu l Sant Pau

  公开号：EP2992880A1

  公开（公告）日：2016-03-09

  The present invention relates to a combination comprising at least an heme oxygenase 1 inducer, and at least a cannabinoid 2 receptor agonist or a selective δ-opioid receptor agonist, for use in the prevention and/or treatment of inflammatory pain.

  本发明涉及一种组合物，至少包含一种血红素加氧酶 1 诱导剂和至少一种大麻素 2 受体激动剂或一种选择性 δ-阿片受体激动剂，用于预防和/或治疗炎症性疼痛。
• METHODS OF INSECT CONTROL
  申请人：Garrity Paul

  公开号：US20110151018A1

  公开（公告）日：2011-06-23

  The present invention is directed towards methods of inhibiting thermo- and chemo-sensing in insects and pests by inhibiting TRPA1 ion gated channel or family members. The present invention is also directed towards methods of insect control by modulating the TRPA1 ion gated channel or family members. The methods are applicable to a wide variety of insects and pests including agricultural and horticultural pests.
• [EN] METHODS OF INSECT CONTROL BY INHIBITING OR MODULATING THE TRPA1 ION GATED CHANNEL OR FAMILY MEMBERS<br/>[FR] PROCÉDÉ DE LUTTE CONTRE LES INSECTES IMPLIQUANT L'INHIBITION OU LA MODULATION DES CANAUX IONIQUES TRPA1 OU DE MEMBRES DE LEUR FAMILLE
  申请人：UNIV BRANDEIS

  公开号：WO2009152261A1

  公开（公告）日：2009-12-17

  The present invention is directed towards methods of inhibiting thermo- and chemo-sensing in insects and pests by inhibiting TRPA1 ion gated channel or family members. The present invention is also directed towards methods of insect control by modulating the TRPA1 ion gated channel or family members. The methods are applicable to a wide variety of insects and pests including agricultural and horticultural pests.