(1R,4E,8E,12R)-13-oxabicyclo[10.1.0]trideca-4,8-diene

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 环氧化物
• 英文名称: (1R,4E,8E,12R)-13-oxabicyclo[10.1.0]trideca-4,8-diene
• 化学式: C₁₂H₁₈O
• 分子量: 178.27
• InChiKey: OWUVDWLTQIPNLN-HPWUHRQSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (1R,4E,8E,12R)-13-oxabicyclo[10.1.0]trideca-4,8-diene 、 盐酸 、 水 以88%的产率得到
  参考文献：
  名称：

  HAUFE, G., SYNTHESIS, 1983, N 3, 235-237

  摘要：

  DOI：
• 作为产物：
  描述：

  反,反,反-1,5,9-环十二烷基三烯 、 甲酸 、 双氧水 生成 (1R,4E,8E,12R)-13-oxabicyclo[10.1.0]trideca-4,8-diene
  参考文献：
  名称：

  HAUFE, G., SYNTHESIS, 1983, N 3, 235-237

  摘要：

  DOI：

文献信息

• Systems and processes for thermolysis of polylactones to produce organic acids
  申请人：Novomer, Inc.

  公开号：US10457624B2

  公开（公告）日：2019-10-29

  Reactor systems and processes produce organic acids through thermolysis of polylactones. The reactor systems and processes introduce at least one epoxide reagent and carbon monoxide reagent to at least one reaction vessel through at least one feed stream inlet. The epoxide reagent and carbon monoxide reagent contact at least one carbonylation catalyst to produce at least one beta-lactone intermediate. The beta-lactone intermediate is polymerized with at least one initiator in the presence of a metal cation to produce at least one polylactone product. The polylactone product is heated under thermolysis conditions to produce at least one organic acid product. The processes control the presence of contaminates, impurities, catalytic materials, and/or reagents to provide for highly pure organic acid products.

  反应器系统和工艺通过热分解聚内酯生产有机酸。反应器系统和工艺通过至少一个进料流入口将至少一种环氧试剂和一氧化碳试剂引入至少一个反应容器。环氧化物试剂和一氧化碳试剂与至少一种羰基化催化剂接触，生成至少一种β-内酯中间体。在金属阳离子存在下，β-内酯中间体与至少一种引发剂聚合，生成至少一种聚内酯产品。聚内酯产品在热分解条件下加热，生成至少一种有机酸产品。这些工艺可控制污染物、杂质、催化材料和/或试剂的存在，以提供高纯度的有机酸产品。
• Processes for producing beta-lactone with heterogenous catalysts
  申请人：Novomer, Inc.

  公开号：US10590099B1

  公开（公告）日：2020-03-17

  The present invention is directed to processes from producing beta-lactone and beta-lactone derivatives using heterogenous catalysts. In preferred embodiments of the present invention, the processes comprise the steps: passing a feed stream comprising an epoxide reagent and a carbon monoxide reagent to a reaction zone; contacting the epoxide reagent and the carbon monoxide reagent with a heterogenous catalyst to produce a beta-lactone product in the reaction zone; and removing the beta-lactone product from the reaction zone. In preferred embodiments, the heterogenous catalyst comprises a solid support containing a cationic Lewis acid functional group and a metal carbonyl compound comprising at least one of anionic metal carbonyl compound or a neutral metal carbonyl compound. In certain preferred embodiments, the epoxide reagent and carbon monoxide reagent have a biobased content.

  本发明涉及使用异质催化剂生产β-内酯和β-内酯衍生物的工艺。在本发明的优选实施方案中，该工艺包括以下步骤：将包含环氧化物试剂和一氧化碳试剂的进料流通入反应区；使环氧化物试剂和一氧化碳试剂与异质催化剂接触，在反应区生成β-内酯产物；从反应区除去β-内酯产物。在优选的实施方案中，异质催化剂包括含有阳离子路易斯酸官能团和金属羰基化合物的固体载体，金属羰基化合物包括阴离子金属羰基化合物或中性金属羰基化合物中的至少一种。在某些优选的实施方案中，环氧化物试剂和一氧化碳试剂具有生物基含量。
• Biobased Carbon Fibers and Carbon Black and Methods of Making the Same
  申请人：Novomer, Inc.

  公开号：US20190002293A1

  公开（公告）日：2019-01-03

  Bio-based materials, e.g., epoxide starting material, a beta-lactone starting material and/or a beta-hydroxy amide starting material, may be used as feedstocks in processes for making and using acrylonitrile and acrylonitrile derivatives to produce, among other products, carbon fibers and carbon black.
• Processes Using Multifunctional Catalysts
  申请人：Novomer, Inc.

  公开号：US20190076834A1

  公开（公告）日：2019-03-14

  The present invention is directed to catalysts and processes for catalyzing two or more chemical reactions with a multifunctional catalyst in a reaction vessel. The processes include steps for introducing one or more reagents to a reaction vessel containing a multifunctional catalyst; contacting the one or more reagents with a first portion of the multifunctional catalyst to produce an intermediate; contacting the intermediate with a second portion of the multifunctional catalyst to produce a product; and removing the product from the reaction vessel. In certain embodiments, the multifunctional catalyst may have a first portion with carbonylation functionality for catalyzing the production of a beta-lactone intermediate from an epoxide reagent and a carbon monoxide reagent. In certain embodiments, the multifunctional catalyst may have a second portion with a functionality suitable for polymerization, co-polymerization, and/or modification of a beta-lactone intermediate. In preferred embodiments, the first portion and second portion are bonded to a heterogenous support.
• PROCESSSES USING MULTIFUNCTIONAL CATALYSTS
  申请人：Novomer, Inc.

  公开号：US20190076835A1

  公开（公告）日：2019-03-14

  The present invention is directed to processes for catalyzing two or more chemical reactions with a multifunctional catalyst in a reaction vessel. The processes include steps for introducing one or more reagents to a reaction vessel containing a multifunctional catalyst; contacting the one or more reagents with a first portion of the multifunctional catalyst to produce an intermediate; contacting the intermediate with a second portion of the multifunctional catalyst to produce a product; and removing the product from the reaction vessel. In certain embodiments, the multifunctional catalyst may have a first portion with carbonylation functionality for catalyzing the production of a beta-lactone intermediate from an epoxide reagent and a carbon monoxide reagent. In certain embodiments, the multifunctional catalyst may have a second portion with a functionality suitable for polymerization, co-polymerization, and/or modification of a beta-lactone intermediate. In preferred embodiments, the first portion and second portion are bonded to a heterogenous support.