丁二醇棕榈酸酯 | 5384-26-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 丁二醇棕榈酸酯
• 英文名称: Hexadecanoic acid--butane-1,4-diol (1/1)
• 英文别名: butane-1,4-diol;hexadecanoic acid
• CAS: 5384-26-9
• 化学式: C20H42O4
• 分子量: 346.5
• InChiKey: OXUIEZRIPVCZPV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  24
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  77.8
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• UV ABSORBER FORMULATIONS
  申请人：Acker Stephanie

  公开号：US20100111884A1

  公开（公告）日：2010-05-06

  Disclosed is a UV filter composition comprising (a) an organic UV absorber of formula (1), wherein R 1 and R 2 , independently of one another, are C 3 -C 18 alkyl; C 2 -C 18 alkenyl; a radical of the formula —CH 2 —CH(OH)—CH 2 —O-T 1 ; or R 1 and R 2 are a radical of the formula (4a); R 7 is a direct bond; a straight-chain or branched C 1 -C 4 alkylene radical or a radical of the formula (I) or (II); R 8 , R 9 and R 10 , independently of one another, are C 1 -C 18 alkyl; C 1 -C 18 alkoxy or a radical of the formula (III); R 11 is C 1 -C 5 alkyl; m 1 is a number from 1 to 4; p 1 is 0; or a number from 1 to 5; A 1 is a radical of the formula (1b), (1c) or (1d); R 3 is hydrogen; C 1 -C 10 alkyl; —(CH 2 CHR 5 —O)n 1 -T 2 ; or —CH 2 —CH(—OH)—CH 2 —O-T 2 ; R 4 is hydrogen; M; C 1 -C 5 alkyl; or —(CH 2 )m 2 —O-T 3 ; R 5 is hydrogen; or methyl; T 1 , T 2 and T 3 independently from each other are hydrogen; or C 1 -C 18 alkyl; Q 1 is C 1 -C 18 alkyl, M is a metal cation; m 2 is 1 to 4; and n 1 is 1-16, (b) dimethyl capramide, (c) a cosmetically acceptable carrier; and water.

  本发明公开了一种紫外线过滤组合物，包括（a）式（1）的有机紫外线吸收剂，其中R1和R2独立地是C3-C18烷基；C2-C18烯基；式—CH2—CH（OH）—CH2—O-T1的基团；或者R1和R2是式（4a）的基团；R7是直链或支链C1-C4烷基、式（I）或（II）的基团；R8、R9和R10独立地是C1-C18烷基、C1-C18烷氧基或式（III）的基团；R11是C1-C5烷基；m1是1至4的数字；p1是0或1至5的数字；A1是式（1b）、（1c）或（1d）的基团；R3是氢、C1-C10烷基、式—（CH2CHR5—O）n1-T2或式—CH2—CH（—OH）—CH2—O-T2；R4是氢、M、C1-C5烷基或式—（CH2）m2—O-T3；R5是氢或甲基；T1、T2和T3互相独立地是氢或C1-C18烷基；Q1是C1-C18烷基，M是金属阳离子；m2是1至4的数字；n1是1-16，（b）二甲基辛酰胺，（c）化妆品可接受载体；和水。
• Diffusion matrix for transdermal drug administration and transdermal drug delivery devices including same
  申请人：CYGNUS THERAPEUTIC SYSTEMS

  公开号：EP0272918A2

  公开（公告）日：1988-06-29

  A solid state, resilient laminated composite for administering a drug transdermally consisting of a top layer of a resilient elastomer; a middle diffusion matrix layer composed of a polyurethane macroporous foam framework in whose pores are embedded a viscoelastic blend of a medical grade polysiloxane adhesive, drug, and optionally a percutaneous absorption enhancer, and a basal surface layer of the medical grade polysiloxane adhesive.

  一种用于经皮给药的固态弹性层压复合材料，由弹性人造橡胶表层、由聚氨酯大孔泡沫框架组成的中间扩散基质层（其孔隙中嵌入了医用级聚硅氧烷粘合剂、药物和经皮吸收促进剂的粘弹性混合物）以及医用级聚硅氧烷粘合剂基底表层组成。
• Solid drug-delivery devices employing fatty acid esters or fatty alcohol ethers of alkanediols as percutaneous absorption enhancers
  申请人：CYGNUS THERAPEUTIC SYSTEMS

  公开号：EP0483105A1

  公开（公告）日：1992-04-29

  A solid state, resilient laminated composite for administering estradiol transdermally consisting of a multiplicity of spaced structural laminas of a resilient elastomer, one of which forms the top of the composite, a viscoelastic hydrophobic polymer lamina containing propylene glycol monolaurate interposed between each structural lamina and a pressure-sensitive adhesive lamina that provides the basal surface of the composite and consists of a blend of a pressure-sensitive adhesive, estradiol, and propylene glycol monolaurate.

  一种用于经皮给药雌二醇的固态弹性层状复合材料，由多个间隔排列的弹性弹性体结构层组成，其中一个结构层构成复合材料的顶部，每个结构层之间有一个含有单月桂酸丙二醇酯的粘弹性疏水聚合物层，以及一个提供复合材料基面的压敏粘合层，该粘合层由压敏粘合剂、雌二醇和单月桂酸丙二醇酯混合组成。
• THICKENING COMPOSITION
  申请人：Ajinomoto Co., Inc.

  公开号：EP1746141A1

  公开（公告）日：2007-01-24

  The present invention provides a thickening composition simultaneously exhibiting suitable thickening performance and superior usability, which contains N-long-chain acyl acidic amino acid and/or a salt thereof, an amphipathic substance, an inorganic salt, and water as essential components, and has a viscosity of not less than 200 mPa·s. By the addition of the thickening composition, moreover, cleansing compositions and cosmetic compositions for skin, hair and the like, which maintain thickening performance and usability, while containing N-long-chain acyl acidic amino acid and/or a salt thereof are provided.

  本发明提供了一种增稠组合物，它同时具有合适的增稠性能和优异的使用性，其主要成分包括 N-长链酰基酸性氨基酸和/或其盐、两性物质、无机盐和水，粘度不低于 200 mPa-s。此外，通过添加该增稠组合物，还可提供用于皮肤、头发等的清洁组合物和化妆品组合物，这些组合物在保持增稠性能和可用性的同时，还含有 N-长链酰基酸性氨基酸和/或其盐。
• Substrates having formulations with improved transferability
  申请人：Kimberly-Clark Worldwide, Inc.

  公开号：US10307351B2

  公开（公告）日：2019-06-04

  Substrates having formulations disposed thereon, wherein the formulations have improved transfer rates from the substrate to skin, are disclosed herein. More particularly, the formulations can be applied to nonwoven, particularly elastomeric substrates, as well as tissue paper, and can be easily and efficiently transferred from the substrate to the skin of a user upon intimate contact thereto. Laminated articles using one or more of the substrates having the formulations disposed thereon are further disclosed.

  本文公开了具有配方的基材，其中的配方具有更高的从基材到皮肤的转移率。更具体地说，这些制剂可以应用于无纺布，特别是弹性基材以及纸巾，并且在与基材亲密接触时，可以轻松有效地从基材转移到使用者的皮肤上。此外，还进一步公开了使用一种或多种基材的层压制品，这些基材上都涂有配方。