丁酸2-(二甲基氨基)乙酯 | 16597-65-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 丁酸2-(二甲基氨基)乙酯
• 英文名称: 2-(Dimethylamino)ethyl butyrate
• 英文别名: butyric acid-(2-dimethylamino-ethyl ester)；Buttersaeure-(2-dimethylamino-aethylester)；1-Butyryloxy-2-dimethylamino-aethan；β-dimethylaminoethyl butyrate；Butanoic acid, 2-(dimethylamino)ethyl ester；2-(dimethylamino)ethyl butanoate
• CAS: 16597-65-2
• 化学式: C₈H₁₇NO₂
• 分子量: 159.228
• InChiKey: NCOVMJHPLAYTJS-UHFFFAOYSA-N

物化性质

• 沸点：
  180-191 °C
• 密度：
  0.909 g/cm3(Temp: 25 °C)

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 海关编码：
  2930200015

反应信息

• 作为反应物：
  描述：

  丁酸2-(二甲基氨基)乙酯 、 苯磺酸甲酯 生成 benzenesulfonic acid ; (2-butyryloxy-ethyl)-trimethyl-ammonium salt
  参考文献：
  名称：

  US2731493

  摘要：

  公开号：
• 作为产物：
  描述：

  p-(Benzoyl)benzyl-N,N-dimethyl-N(butanoyloxyethyl)ammonium triphenyl-n-butylborate 以 乙腈 为溶剂， 生成 丁酸2-(二甲基氨基)乙酯
  参考文献：
  名称：

  Sarker, Ananda M.; Lungu, Adrian; Mejiritski, Alexander, Journal of the Chemical Society. Perkin Transactions 2 (2001), 1998, # 10, p. 2315 - 2331

  摘要：

  DOI：

文献信息

• [EN] LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS<br/>[FR] LIPIDES ET COMPOSITIONS LIPIDIQUES DESTINÉS À LA LIBÉRATION D'AGENTS ACTIFS
  申请人：NOVARTIS AG

  公开号：WO2015095346A1

  公开（公告）日：2015-06-25

  This invention provides for a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein R1-R3, n, p, L1 and L2 are defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues.

  这项发明提供了一种式（I）的化合物或其药学上可接受的盐，其中R1-R3、n、p、L1和L2在此处被定义。式（I）的化合物及其药学上可接受的盐是阳离子脂质，在将生物活性剂传递给细胞和组织方面非常有用。
• [EN] FOOD SUPPLEMENT AND COMPOSITION COMPRISING CHOLINE BUTYRATE SALT AND/OR BUTYRYLCHOLINE<br/>[FR] COMPLÉMENT ALIMENTAIRE ET COMPOSITION COMPRENANT UN SEL DE BUTYRATE DE CHOLINE ET/OU DE LA BUTYRYLCHOLINE
  申请人：ABERGAVENNY NV

  公开号：WO2017187335A1

  公开（公告）日：2017-11-02

  The present Invention relates to the use of choline butyrate or butyrylcholine in food and in particular in the treatment of Intestinal disorders and in the stimulation of the brain development. Furthermore, the invention provides for a food supplement and a pharmaceutical composition comprising choline butyrate or butyrylcholine, The invention also relates to an animal feed comprising choline butyrate or butyrylcholine or said food supplement.

  本发明涉及在食品中使用胆碱丁酸盐或丁酰胆碱，特别是在治疗肠道疾病和促进大脑发育方面的应用。此外，该发明提供了一种食品补充剂和包含胆碱丁酸盐或丁酰胆碱的药物组合物。该发明还涉及一种含有胆碱丁酸盐或丁酰胆碱或上述食品补充剂的动物饲料。
• Photosensitive intramolecular electron transfer compounds
  申请人：Spectra Group Limited, Inc.

  公开号：US05998496A1

  公开（公告）日：1999-12-07

  A compound of the general formula: A-L.sup.+ D.sup.- where A is a moiety which absorbs radiation and enters an excited state in which it accepts an electron; D.sup.- is a moiety which donates an electron to the excited state A and releases a free radical; and L.sup.+ is a cationic linking group which tethers electron acceptor moiety A to electron donor moiety D.sup.-. Cationic linking moiety L.sup.+ has the formula: -L'-G- where L' is a moiety which forms a stable radical with acceptor moiety A upon transfer of an electron from donor moiety D.sup.- to electron acceptor moiety A, and G is a moiety which forms a leaving group upon transfer of the electron from donor moiety D.sup.- to acceptor moiety A.

  通式为：A-L.sup.+ D.sup.-的化合物，其中A是一个吸收辐射并进入激发态以接受电子的基团；D.sup.-是一个给予激发态A电子并释放自由基的基团；L.sup.+是一个阳离子连接基团，将电子受体基团A与电子给体基团D.sup.-连接在一起。阳离子连接基团L.sup.+的化学式为：-L'-G-，其中L'是一个在从给体基团D.sup.-到电子受体基团A的电子转移过程中与受体基团A形成稳定自由基的基团，G是一个在从给体基团D.sup.-到受体基团A的电子转移过程中形成脱离基团的基团。
• Block copolymer
  申请人：JSR CORPORATION

  公开号：US10308752B2

  公开（公告）日：2019-06-04

  A block copolymer includes a polystyrene block including a styrene unit, and a polyalkyl (meth)acrylate block including an alkyl (meth)acrylate unit. The block copolymer includes an organic group that is bound to at least one end of a main chain of the block copolymer and that comprises a hetero atom. A polymerization initiation end of the block copolymer includes a structure derived from an alkyl lithium. The organic group included in the block copolymer includes a nitrogen atom, a sulfur atom, a phosphorus atom, a tin atom, or a combination thereof, or is represented by formula (1). R1 represents a single bond or a divalent organic group having 1 to 30 carbon atoms; and R2 represents a hydrogen atom, an aliphatic linear hydrocarbon group having 1 to 30 carbon atoms, an alicyclic hydrocarbon group having 3 to 30 carbon atoms, or the like.

  嵌段聚合物包括聚苯乙烯嵌段（包括苯乙烯单元）和聚烷基（甲基）丙烯酸酯嵌段（包括烷基（甲基）丙烯酸酯单元）。该嵌段共聚物包括与嵌段共聚物主链至少一端结合的有机基团，该有机基团包含杂原子。嵌段共聚物的聚合起始端包括一个由烷基锂衍生的结构。嵌段共聚物中包含的有机基团包括氮原子、硫原子、磷原子、锡原子或它们的组合，或者由式（1）表示。R1 代表单键或具有 1 至 30 个碳原子的二价有机基团；R2 代表氢原子、具有 1 至 30 个碳原子的脂族线性烃基、具有 3 至 30 个碳原子的脂环烃基或类似基团。
• Composition and pattern-forming method
  申请人：JSR CORPORATION

  公开号：US10995173B2

  公开（公告）日：2021-05-04

  A directed self-assembling composition for pattern formation includes a block copolymer. The block copolymer includes a polystyrene block having a styrene unit, and a polyalkyl (meth)acrylate block having an alkyl (meth)acrylate unit. The block copolymer has a group that is bound to at least one end of a main chain of the block copolymer and that includes a hetero atom.

  一种用于图案形成的定向自组装组合物包括嵌段共聚物。嵌段聚合物包括具有苯乙烯单元的聚苯乙烯嵌段和具有烷基（甲基）丙烯酸酯单元的聚烷基（甲基）丙烯酸酯嵌段。嵌段聚合物具有与嵌段共聚物主链至少一端结合的基团，该基团包括杂原子。