七氟丁酰溴 | 375-13-3

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 中文名称: 七氟丁酰溴
• 中文别名: 3,3,5-三甲基环己基羟基(苯基)乙酸酯-7-(2-羟基乙基)-1,3-二甲基-3,7-二氢-1H-嘌呤-2,6-二酮(1:1)
• 英文名称: heptafluorobutyryl bromide
• 英文别名: Heptafluor-butyrylbromid；Perfluorbutyrylbromid；Heptafluorobutanoyl bromide；2,2,3,3,4,4,4-heptafluorobutanoyl bromide
• CAS: 375-13-3
• 化学式: C₄BrF₇O
• 分子量: 276.936
• InChiKey: PJYLUIOQPJDGIG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  8

安全信息

• 海关编码：
  2915900090

反应信息

• 作为反应物：
  描述：

  七氟丁酰溴 生成 七氟丙基溴
  参考文献：
  名称：

  The Photolysis of Polyfluoroacyl Fluorides, Chlorides, and Bromides

  摘要：

  DOI：

  10.1021/jo01018a016
• 作为产物：
  描述：

  七氟丁酸 在 磷化氢 、 溴 作用下， 生成 七氟丁酰溴
  参考文献：
  名称：

  Process for making of fluorocarbon derivatives

  摘要：

  公开号：

  US02704776A1
• 作为试剂：
  描述：

  六氟丙烯 在 七氟丁酰溴 作用下， 生成 七氟丙基溴 、 1,4-dibromo-1,1,2,3,4,4-hexafluoro-2,3-bis-trifluoromethyl-butane 、 1-bromo-1,1,2,3,3,4,4,5,5,5-decafluoro-2-trifluoromethyl-pentane 、 2-bromo-2H,4H-hexadecafluoro-4-trifluoromethyl-octane
  参考文献：
  名称：

  The Photolysis of Polyfluoroacyl Fluorides, Chlorides, and Bromides

  摘要：

  DOI：

  10.1021/jo01018a016

文献信息

• Perfluorinated cyclohexyl carboxylic acid and cyclohexyl acetic acid and derivatives
  申请人：MINNESOTA MINING &

  公开号：US02593737A1

  公开（公告）日：1952-04-22
• Fukui et al., Nippon Kagaku Zasshi, 1959, vol. 80, p. 541,543
  作者：Fukui et al.

  DOI：——

  日期：——
• DE836796
  申请人：——

  公开号：——

  公开（公告）日：——
• Fluorocarbon acids and derivatives
  申请人：MINNESOTA MINING &

  公开号：US02567011A1

  公开（公告）日：1951-09-04
• Suicidal behavior—symptom or disorder?
  作者：B. Ahrens、M. Linden、H. Zäske、H. Berzewski

  DOI：10.1016/s0010-440x(00)80017-6

  日期：2000.3

  This article examines the diagnostic status of suicidal ideation with and without additional signs of defined or subthreshold mental disorders. Data from the World Health Organization (WHO) study on Psychological Problems in General Health Care (PPGHC) show that 8.8% of all general practice patients report that they recently had a wish to be dead. Among patients with acute depressive episodes, the rate is 34.5%, as compared with 1.3% in persons without any sign of mental disorder. Rates of suicidal ideation in persons with subthreshold disorders (10.4%) are similar to the rate in persons with other, nondepressed forms of mental disorders (12.9%). Still, 30.1% of all persons with suicidal ideation do not have a defined mental disorder, and 21.5% do not even have subthreshold disorders. But in these persons also, suicidal ideation is associated with an increased rate of depressive complaints. Suicidal ideation therefore, in any case, can be seen as an indicator of mental problems. But it seems impossible to lower the thresholds of defined mental disorders so that all forms of suicidal ideation will be covered. Instead, suicidal thoughts must be regarded as a symptom with the status of a disorder itself which should be handled as a comorbid condition if other mental disorders co-occur, Copyright (C) 2000 by W.B. Saunders Company.