Tetradecanedioic acid monobutyl ester

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Tetradecanedioic acid monobutyl ester
• 英文别名: 14-Butoxy-14-oxotetradecanoic acid
• 化学式: C₁₈H₃₄O₄
• 分子量: 314.466
• InChiKey: ACMXHMKISSSQBO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  22
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

上下游信息

• 上游原料

  中文名称	英文名称	CAS号	化学式	分子量
  十四烷二酸	1,14-tetradecanedioic acid	821-38-5	C14H26O4	258.358
  乙酸丁酯	acetic acid butyl ester	123-86-4	C6H12O2	116.16

反应信息

• 作为产物：
  描述：

  乙酸丁酯 、 十四烷二酸 在 Dowex 50Wx₂ 作用下， 以 正辛烷 为溶剂， 反应 25.0h， 以80%的产率得到Tetradecanedioic acid monobutyl ester
  参考文献：
  名称：

  Selective monoesterification of dicarboxylic acids catalysed by ion-exchange resins

  摘要：

  具有4至14个碳原子的对称二羧酸在强酸性离子交换树脂催化下的转酯化反应中，可以在酯-烃混合物中高选择性地获得相应的单酯，产率很高。研究发现，二羧酸的酯化速率远高于形成的单羧酸的速率。这一结果可以解释单酯形成的高选择性，也可以通过树脂表面存在的水层来解释。这种选择性酯化方法相当简单且实用。

  DOI：

  10.1039/a902325i

文献信息

• Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes
  申请人：McDaniel C. Steven

  公开号：US20100210745A1

  公开（公告）日：2010-08-19

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peotide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文公开了一些聚合材料，如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；一种表面处理，如纺织品涂层或蜡；一种填料，用于这样的聚合材料或表面处理，其中包括一种酶，如酯酶（例如，脂肪水解酶，硫酸酯水解酶，有机磷化合物降解酶），降解细胞壁和/或细胞膜成分的酶（例如，溶菌酶，裂解转糖基酶），生物杀菌或生物静态肽，以及/或肽酶。本文还公开了通过将酶纳入可通过脂肪水解酶、水解酶和/或脲酶的活性交联材料中来改变材料性能，如使用寿命、柔韧性或刚度的方法。
• Anti-fouling Paints and Coatings
  申请人：Reactive Surfaces LTD

  公开号：US20150191607A1

  公开（公告）日：2015-07-09

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peptide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文披露了聚合材料，例如涂层、塑料、层压材料、复合材料、弹性体、粘合剂或密封剂；表面处理，例如纺织品整理或蜡；填充剂，用于这种聚合材料或表面处理，包括酯酶（例如脂肪水解酶、硫酸酯水解酶、有机磷化合物降解酶）的酶，降解细胞壁和/或细胞膜成分的酶（例如溶菌酶、裂解转葡糖苷酶），生物杀菌或生物稳定肽，和/或肽酶。本文还披露了通过将酶并入能够通过脂肪水解酶、水解酶和/或脲酶的活性进行化学交联的材料中，改变材料性能（例如使用寿命、柔韧性或刚度）的方法。
• Convenient selective monoesterification of α, ω-dicarboxylic acids catalyzed by ion-exchange resins
  作者：Masahiko Saitoh、Shizuo Fujisaki、Yasuhiro Ishii、Takeshi Nishiguchi

  DOI：10.1016/s0040-4039(96)01454-2

  日期：1996.9

  Symmetric dicarboxylic acids, ranging from pentanedioic acid to tetradecanedioic acid, gave selectively the corresponding monoesters in high yields in the transesterification catalyzed by strongly acidic ion-exchange resins in ester/octane mixtures. Copyright (C) 1996 Elsevier Science Ltd
• Selective monoesterification of dicarboxylic acids catalysed by ion-exchange resins
  作者：Takeshi Nishiguchi、Yasuhiro Ishii、Shizuo Fujisaki

  DOI：10.1039/a902325i

  日期：——

  Symmetrical dicarboxylic acids with 4–14 carbon atoms gave selectively the corresponding monoesters in high yields in the transesterification catalysed by strongly acidic ion-exchange resins in ester–hydrocarbon mixtures. It was found that the rate of the esterification of the dicarboxylic acids is much higher than that of the monocarboxylic acids formed. This result can explain the high selectivity for the monoester formation and can also be explained by the existence of an aqueous layer on the surface of the resins. This method of selective esterification is quite simple and practical.

  具有4至14个碳原子的对称二羧酸在强酸性离子交换树脂催化下的转酯化反应中，可以在酯-烃混合物中高选择性地获得相应的单酯，产率很高。研究发现，二羧酸的酯化速率远高于形成的单羧酸的速率。这一结果可以解释单酯形成的高选择性，也可以通过树脂表面存在的水层来解释。这种选择性酯化方法相当简单且实用。