(R)-7,7'-bis[(O,O'-bis(o-diphenylphosphinobenzoyl))hydroxy]-2,2'-dimethoxy-1,1'-binaphthyl

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (R)-7,7'-bis[(O,O'-bis(o-diphenylphosphinobenzoyl))hydroxy]-2,2'-dimethoxy-1,1'-binaphthyl
• 英文别名: [8-[7-(2-Diphenylphosphanylbenzoyl)oxy-2-methoxynaphthalen-1-yl]-7-methoxynaphthalen-2-yl] 2-diphenylphosphanylbenzoate；[8-[7-(2-diphenylphosphanylbenzoyl)oxy-2-methoxynaphthalen-1-yl]-7-methoxynaphthalen-2-yl] 2-diphenylphosphanylbenzoate
• 化学式: C₆₀H₄₄O₆P₂
• 分子量: 922.953
• InChiKey: AJRFFIFOXSHPPA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  14.2
• 重原子数：
  68
• 可旋转键数：
  15
• 环数：
  10.0
• sp3杂化的碳原子比例：
  0.03
• 拓扑面积：
  71.1
• 氢给体数：
  0
• 氢受体数：
  6

上下游信息

• 上游原料

  中文名称	英文名称	CAS号	化学式	分子量
  ——	(R)-(-)-7,7'-Bis(benzyloxy)-2,2'-dimethoxy-1,1'-binaphthyl	——	C36H30O4	526.632
  ——	(S)-(+)-7,7'-Dihydroxy-2,2'-dimethoxy-1,1'-binaphthyl	——	C22H18O4	346.383

反应信息

• 作为产物：
  描述：

  (R)-(-)-7,7'-Bis(benzyloxy)-2,2'-dimethoxy-1,1'-binaphthyl 在 palladium dihydroxide 4-二甲氨基吡啶 、 氢气 、 N,N'-二环己基碳二亚胺 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 20.0 ℃ 、101.33 kPa 条件下， 反应 1.0h， 生成 (R)-7,7'-bis[(O,O'-bis(o-diphenylphosphinobenzoyl))hydroxy]-2,2'-dimethoxy-1,1'-binaphthyl
  参考文献：
  名称：

  C2-Symmetric Bisphosphine Ligands Derived from 1,1′-Binaphthyldiamines and Diphenylphosphinobenzoic Acid for Palladium Catalyzed Desymmetrizations

  摘要：

  A series of novel C-2-symmetric bisphosphine ligands derived from DPPBA and C-2-symmetric 1,1'-binaphthyldiamines has been synthesized. In palladium catalyzed desymmetrization of meso cyclic carbamates, the enantioselectivity and the stereochemistry of the major enantiomers are largely affected by the substitution position of DPPBA moiety on the 1,1'-binaphthyl chiral scaffold. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(00)00420-8

文献信息

• C2-Symmetric Bisphosphine Ligands Derived from 1,1′-Binaphthyldiamines and Diphenylphosphinobenzoic Acid for Palladium Catalyzed Desymmetrizations
  作者：Chung Woo Lim、Sang-gi Lee

  DOI：10.1016/s0040-4020(00)00420-8

  日期：2000.7

  A series of novel C-2-symmetric bisphosphine ligands derived from DPPBA and C-2-symmetric 1,1'-binaphthyldiamines has been synthesized. In palladium catalyzed desymmetrization of meso cyclic carbamates, the enantioselectivity and the stereochemistry of the major enantiomers are largely affected by the substitution position of DPPBA moiety on the 1,1'-binaphthyl chiral scaffold. (C) 2000 Elsevier Science Ltd. All rights reserved.