1-dioxolanyl-2,3-dihydro-1H-indene

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: 1-dioxolanyl-2,3-dihydro-1H-indene
• 英文别名: 2-indanyl-1,3-dioxolane；2-(2,3-dihydro-1H-inden-1-yl)-1,3-dioxolane
• 化学式: C₁₂H₁₄O₂
• 分子量: 190.242
• InChiKey: ALLYMHNPYIWABA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1,2-二氢萘 、 乙二醇 在 thallium(III) nitrate 作用下， 反应 0.25h， 以65%的产率得到1-dioxolanyl-2,3-dihydro-1H-indene
  参考文献：
  名称：

  Thallium trinitrate-mediated ring contraction of 1,2-dihydronaphthalenes: an approach to the synthesis of indans

  摘要：

  Oxidation of 1,2-dihydronaphthalenes with thallium trinitrate was studied. 1,2-dihydronaphthalene, 1-methyl-1,2-dihydronaphthalene, 6- and 8-methoxy-1,2-dihydronaphthalenes gave rise to the respective ring contraction products in good yields, whereas the rearrangement was not observed using 4-methyl-1,2-dihydronaphthalene and 1-n-butyl-4-methyl-1,2-dihydronaphthalene as substrates. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(00)01174-1

文献信息

• US6342612B1
  申请人：——

  公开号：US6342612B1

  公开（公告）日：2002-01-29
• US6362141B1
  申请人：——

  公开号：US6362141B1

  公开（公告）日：2002-03-26
• Thallium trinitrate-mediated ring contraction of 1,2-dihydronaphthalenes: an approach to the synthesis of indans
  作者：Helena M.C Ferraz、Luiz F Silva、Tiago O Vieira

  DOI：10.1016/s0040-4020(00)01174-1

  日期：2001.2

  Oxidation of 1,2-dihydronaphthalenes with thallium trinitrate was studied. 1,2-dihydronaphthalene, 1-methyl-1,2-dihydronaphthalene, 6- and 8-methoxy-1,2-dihydronaphthalenes gave rise to the respective ring contraction products in good yields, whereas the rearrangement was not observed using 4-methyl-1,2-dihydronaphthalene and 1-n-butyl-4-methyl-1,2-dihydronaphthalene as substrates. (C) 2001 Elsevier Science Ltd. All rights reserved.