1,3,3,10-tetramethyl-1,3a,4,10b-tetrahydro-3H-isoxazolo[3',4':3,4]pyrrolo[1,2-a]indole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 1,3,3,10-tetramethyl-1,3a,4,10b-tetrahydro-3H-isoxazolo[3',4':3,4]pyrrolo[1,2-a]indole
• 英文别名: 8,11,13,13-tetramethyl-12-oxa-1,11-diazatetracyclo[7.6.0.02,7.010,14]pentadeca-2,4,6,8-tetraene
• 化学式: C₁₆H₂₀N₂O
• 分子量: 256.348
• InChiKey: AZCXNHBIWMIHLQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  19
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  17.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N-甲基羟胺 、 3-甲基-1-(3-甲基丁-2-烯基)吲哚-2-甲醛 反应 0.2h， 以78%的产率得到1,3,3,10-tetramethyl-1,3a,4,10b-tetrahydro-3H-isoxazolo[3',4':3,4]pyrrolo[1,2-a]indole
  参考文献：
  名称：

  Microwave Induced 1,3-Depolar Cycloaddition Reactions of Nitrones

  摘要：

  1,3-Dipolar cycloaddition reactions involving unreactive nitrones have been carried out successfully under microwave irradiations. The reaction of nitrones 1 and alkene 2 proceeded regiospecifically at atmospheric pressure and the corresponding isoxazolidines 3 were obtained in high yields.

  DOI：

  10.1080/00397919708004124

文献信息

• Microwave Induced 1,3-Depolar Cycloaddition Reactions of Nitrones
  作者：Bipul Baruah、Dipak Prajapati、Anima Baruah、Jagir S. Sandhu

  DOI：10.1080/00397919708004124

  日期：1997.8

  1,3-Dipolar cycloaddition reactions involving unreactive nitrones have been carried out successfully under microwave irradiations. The reaction of nitrones 1 and alkene 2 proceeded regiospecifically at atmospheric pressure and the corresponding isoxazolidines 3 were obtained in high yields.