A method of treating a surface so that the antimicrobial activity of water-soluble antimicrobial agents is retained at the surface despite repeated washing with water is described. The method uses a dispersion of a lipidated polyanionic molecule and one or more antimicrobial agents in an aqueous carrier such as water. The treatment of the surface of the fabric of adhesive bandages and stainless steel is demonstrated using a combination of crystal violet and silver nitrate as the antimicrobial agents. The method has application in the treatment of such surfaces to control microbial growth and the development of biofilms.
描述了一种处理表面的方法,使
水溶性抗菌剂的抗菌活性在表面上尽管反复用
水洗涤仍然保持。该方法使用脂质化聚阴离子分子和一个或多个抗菌剂的分散体在
水等
水性载体中。使用
结晶紫和
硝酸银的组合作为抗菌剂,演示了对胶布和不锈钢的表面进行处理。该方法在处理这些表面以控制微
生物生长和
生物膜发展方面具有应用。