oxalic acid triethanolammonium salt

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: oxalic acid triethanolammonium salt
• 英文别名: triethanolammonium hydrogenoxalate；2-[Bis(2-hydroxyethyl)amino]ethanol;oxalic acid
• 化学式: C₂H₂O₄*C₆H₁₅NO₃
• 分子量: 239.225
• InChiKey: BKTDITUACHTMQR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.58
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  139
• 氢给体数：
  5
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  草酸 、 三乙胺 以 甲醇 为溶剂， 反应 1.0h， 以90%的产率得到oxalic acid triethanolammonium salt
  参考文献：
  名称：

  基于二羧酸（草酸，丙二酸，琥珀酸）的三乙醇铵盐的离子液体。晶体结构和阳离子-阴离子相互作用

  摘要：

  合成了一系列基于二羧酸（草酸，丙二酸和琥珀酸）的三乙醇铵盐的离子液体，并通过IR和H 1，C 13 NMR光谱，热重分析（TGA）和差示扫描量热法（DSC）对其进行了表征。它们的结构通过单晶X射线衍射确定。结果发现，三乙醇[（HOCH 2 CH 2）3 NH] +草酸（盐阳离子1），丙二酸（2）和琥珀酸（3含一价阴离子）[OOC（CH 2）Ñ COOH] - （Ñ  = 0–2）分子内部构象，并且铵质子（H am）驻留在由3个与氮原子连接的CH 2 CH 2 OH分支形成的“灯罩”内部。琥珀酸盐（4）的第二种修饰的不对称电池包含两个三乙醇铵阳离子和一个琥珀酸二阴离子[（HOCH 2 CH 2）3 NH] 2 + [OOC（CH 2）2 COO] 2-。在该盐（4）中，三乙醇铵阳离子的一个CH 2 CH 2 OH分支绕N C键旋转（内-外构象）并形成无限的TEA链。首先在TEA的有机盐中发现

  DOI：

  10.1016/j.molliq.2016.12.111

文献信息

• Triethanolammonium salts of biologically active carboxylic acids
  作者：Yu. A. Kondratenko、T. A. Kochina、V. S. Fundamensky、Yu. G. Vlasov

  DOI：10.1134/s1070363215120075

  日期：2015.12

  Triethanolammonium salts (protatranes) of biologically active carboxylic acids (nicotinic, cinnamic, benzoic, salicylic, oxalic, malonic, succinic, malic, citric) were synthesized in yields exceeding 90%. The structure of the synthesized compounds was studied by IR spectroscopy and X-ray diffraction analysis.

  合成的生物活性羧酸（烟酸，肉桂酸，苯甲酸，水杨酸，草酸，丙二酸，琥珀酸，苹果酸，柠檬酸）的三乙醇铵盐（protatranes）的收率超过90％。通过红外光谱和X射线衍射分析研究了合成化合物的结构。
• Production process of cross-linked polyaspartic acid resin
  申请人：MITSUI CHEMICALS, INC.

  公开号：EP0866084A2

  公开（公告）日：1998-09-23

  A process is disclosed for producing with good productivity a cross-linked polyaspartic acid resin having biodegradability and high water absorbency. The process features inclusion of one of the following steps: (a) a polysuccinimide, which has been brought into a dispersed state by a dispersant, and a cross-linking agent are reacted to produce the cross-linked polyaspartic acid resin; (b) imide rings of a cross-linked polysuccinimide are subjected to a hydrolysis reaction while controlling a swelling degree of a resulting gel, whereby the cross-linked polyaspartic acid resin is produced; and (c) a gel of a cross-linked polysuccinimide, which has been obtained by reacting a cross-linking agent to a solution of a polysuccinimide in an organic solvent, is disintegrated to subject imide rings of the cross-linked polysuccinimide to a hydrolysis reaction, so that the cross-linked polyaspartic acid resin is produced. The process may also include one or both of the following steps as needed: (d) a gel of the cross-linked polyaspartic acid resin is washed with water and/or a water-miscible organic solvent; and (e) the polysuccinimide is produced using a basic amino acid as a cross-linking agent.

  本发明公开了一种工艺，用于生产具有生物降解性和高吸水性的交联聚天冬氨酸树脂，生产效率高。该工艺的特点是包含以下步骤之一：(a) 通过分散剂使聚琥珀酰亚胺进入分散状态，并与交联剂反应，生成交联聚天冬氨酸树脂；(b) 将交联聚琥珀酰亚胺的酰亚胺环进行水解反应，同时控制所得凝胶的溶胀度，从而生成交联聚天冬氨酸树脂；(c) 将交联剂与聚琥珀酰亚胺在有机溶剂中的溶液反应而得到的交联聚琥珀酰亚胺凝胶分解，使交联聚琥珀酰亚胺的酰亚胺环发生水解反应，从而制得交联聚天冬氨酸树脂。根据需要，该工艺还可包括以下一个或两个步骤：(d) 用水和/或水混溶有机溶剂洗涤交联聚天冬氨酸树脂的凝胶；(e) 使用碱性氨基酸作为交联剂生产聚琥珀酰亚胺。
• Biological Activity of Protic Ionic Liquids Based on Tris(2-hydroxyethyl)ammonium Salts and the Crystal Structure of Tris(2-hydroxyethyl)ammonium Malate
  作者：Yu. A. Kondratenko、V. V. Gurzhii、G. G. Panova、L. M. Anikina、O. R. Udalova、V. I. Krutikov、V. L. Ugolkov、T. A. Kochina

  DOI：10.1134/s0036023620090089

  日期：2020.9

  The antimicrobial and growth-stimulating activities of nine protic ionic liquids (PILs)-tris(2-hydroxyethyl)ammonium salts (protatranes) of cinnamic, benzoic, salicylic, oxalic, malonic, succinic, malic and citric acids-were investigated for the first time. It was found that tris(2-hydroxyethyl)ammonium salts of cinnamic, benzoic and malonic acids have a positive impact on seeds germination and growth characteristics of garden cress (Lepidium sativumL.) sprouts. All the investigated PILs exhibited selective activity againstStaphylococcus aureusbacteria.PILs based on tris(2-hydroxyethyl)ammonium malate with the melting point of 41 degrees C were isolated as crystals to perform a comparative study of the crystal structure by single-crystal X-ray diffraction. In contrast to cations in tris(2-hydroxyethyl)ammonium succinate, cations in malate have a tricyclicendoconformation that is most typical of tris(2-hydroxyethyl)ammonium salts.
• US6072024A
  申请人：——

  公开号：US6072024A

  公开（公告）日：2000-06-06
• US6346569B1
  申请人：——

  公开号：US6346569B1

  公开（公告）日：2002-02-12