乙二醇二新戊酸酯 | 20267-20-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 乙二醇二新戊酸酯
• 英文名称: ethylene glycol di(2,2-dimethylpropanoate)
• 英文别名: ethylene glycol dipivalate；ethylene dipivalate；Ethylenglycoldineopentanoat；1,2-Dipivaloyloxy-aethan；Aethylenglykol-dipivalat；1,2-Dipivaloyloxyaethan；2-(2,2-dimethylpropanoyloxy)ethyl 2,2-dimethylpropanoate
• CAS: 20267-20-3
• 化学式: C₁₂H₂₂O₄
• 分子量: 230.304
• InChiKey: CECHHHFZXNTPMP-UHFFFAOYSA-N

物化性质

• LogP：
  2.769 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

安全信息

• 海关编码：
  2915900090

反应信息

• 作为反应物：
  描述：

  乙二醇二新戊酸酯 、 N-甲基对甲苯磺酰胺 在 hafnium(IV) trifluoromethanesulfonate 作用下， 反应 14.0h， 以78%的产率得到
  参考文献：
  名称：

  一种制备氨基醇衍生物的方法

  摘要：

  本发明提供了一种制备氨基醇衍生物的方法，其特征在于，包括对二元或多元醇羧酸酯的酯基进行取代反应，得到氨基醇衍生物，所述氨基醇衍生物中，氨基衍生为磺酰胺基，并至少保留一个羧酸酯基。本发明原料廉价易得，催化剂用量低，反应条件简单，产物选择性高。

  公开号：

  CN108707096B
• 作为产物：
  描述：

  乙二醇 、 三甲基乙酸 在 磷酸 、 苯 作用下， 反应 8.0h， 生成 乙二醇二新戊酸酯
  参考文献：
  名称：

  Saturation vapor pressures and vaporization enthalpies of esters of ethylene glycol and lower carboxylic acids

  摘要：

  Saturation vapor pressures and vaporization enthalpies of ethylene glycol and C-1-C-5 carboxylic acid disubstituted esters of normal and branched structures are determined by the transfer method in the temperature range of 295 to 327 K. Dependences of vaporization enthalpies versus the number of carbon atoms in a molecule and the retention indices are determined. An analysis of existing calculation schemes is given to help predict the vaporization enthalpy of the compounds under study.

  DOI：

  10.1134/s0036024411100116

文献信息

• A Mild and Efficient Chemoselective Protection of Primary Alcohols as Pivaloyl Esters Using La(NO₃)₃·6H₂O as a Catalyst under Solvent-free Conditions
  作者：P. Prabhakar、N. Suryakiran、Y. Venkateswarlu

  DOI：10.1246/cl.2007.732

  日期：2007.6.5

  Primary alcohols are selectively and efficiently protected as their pivaloyl esters with pivaloyl chloride in the presence of catalytic amounts of La(NO3)3·6H2O at room temperature under solvent-free conditions in excellent yields.

  主醇能够在无溶剂条件下，在催化量的六水合硝酸镧存在下，室温时以高产率选择性地高效转化为它们的特戊酰酯，使用的是特戊酰氯。
• METHOD FOR PRODUCING TETRAFLUORO COMPOUND
  申请人：Miyashita Yasuhiro

  公开号：US20110178323A1

  公开（公告）日：2011-07-21

  Provided is a method for producing a tetrafluoro nitrogen-containing heterocyclic compound such as tetrafluoropyrrolidine in good yield and at low cost. The method comprises the steps of: (A) reacting a compound represented by the formula (I) with fluorine gas to produce a tetrafluoro compound represented by the formula (II), (B) converting the tetrafluoro derivative represented by the formula (II) to a compound represented by the formula (III), and (C) reacting the compound represented by the formula (III) with an amine compound represented by the formula NH 2 R 9 to produce a tetrafluoro nitrogen-containing heterocyclic compound represented by the formula (IV) or salt thereof.

  提供了一种生产四氟氮含杂环化合物（如四氟吡咯烷）的方法，产率高且成本低。该方法包括以下步骤：（A）将式（I）表示的化合物与氟气反应，生成式（II）表示的四氟化合物，（B）将式（II）表示的四氟衍生物转化为式（III）表示的化合物，以及（C）将式（III）表示的化合物与式NH2R9表示的胺化合物反应，生成式（IV）表示的四氟氮含杂环化合物或其盐。
• Cellulose Compound Film, Optical Compensation Sheet, Polarizing Plate, and Liquid Crystal Display Device
  申请人：Nozoe Yutaka

  公开号：US20070259134A1

  公开（公告）日：2007-11-08

  A cellulose compound film containing a cellulose compound having two or more substituents whose polarizability anisotropies Δα calculated by mathematical formula (1) are different from each other, wherein substitution degrees of the following substituents A and B in the cellulose compound satisfy relationship as defined by mathematical formula (A1), in which the substituent A has the lowest Δα and the substituent B has the highest Δα: Δ ⁢ ⁢ α = α ⁢ ⁢ x - α ⁢ ⁢ y + α ⁢ ⁢ z 2 Mathematical ⁢ ⁢ formula ⁢ ⁢ ( 1 ) wherein, in characteristic values obtained after diagonalization of polarizability tensor, αx is the largest component, αy is the second largest component, and αz is the smallest component; DS B 2+ DS B 3− DS B 6≧−0.1   Mathematical formula (A1) wherein DS B 2, DS B 3, and DS B 6 represent a substitution degree of the substituent B at the 2-, 3-, or 6-position of a β-glucose ring constituting unit of cellulose, respectively; and an optical compensation film, a polarizing plate, and a liquid crystal display device, using the cellulose compound film.

  一种纤维素化合物薄膜，其含有具有两个或更多取代基的纤维素化合物，其极化率各向异性Δα通过数学公式（1）计算得出，其中以下取代基A和B的取代度满足数学公式（A1）所定义的关系，其中取代基A具有最低的Δα，而取代基B具有最高的Δα：Δα = αx-αy + αz2数学公式（1）其中，在极化率张量对角化后获得的特征值中，αx是最大分量，αy是第二大分量，αz是最小分量;DSB2 + DSB3-DSB6≥-0.1数学公式（A1）其中DSB2、DSB3和DSB6分别表示取代基B在纤维素构成单位β-葡萄糖环的2-、3-或6-位置的取代度;以及使用该纤维素化合物薄膜的光学补偿膜、偏光板和液晶显示装置。
• Cellulose Acylate Film, Method of Producing the Same, Cellulose Derivative Film, Optically Compensatory Film Using the Same, Optically-Compensatory Film Incorporating Polarizing Plate, Polarizing Plate and Liquid Crystal Display Device
  申请人：Haruta Hiromoto

  公开号：US20090290100A1

  公开（公告）日：2009-11-26

  A method of producing a cellulose derivative film, the method comprising: forming a film with a solvent cast method from a dope including a cellulose derivative satisfying following conditions (a) and (b): (a) at least one among three hydroxyl groups included in a glucose unit of cellulose is substituted by a substituent of which a polarizability anisotropy Δα represented as following Expression (1) is 2.5×10 −24 cm 3 or higher: Expression (1): Δα=αx−(αy+αz)/2, wherein αx, αy and αz is as defined in the specification; and (b) when a substitution degree by a substituent of which Δα is 2.5×10 −24 cm 3 or higher is P A , and a substitution degree by a substituent of which Δα is lower than 2.5×10 −24 cm 3 is P B , the P A and P B satisfy following Expressions (3) and (4): Expression (3): 2P A +P B >3.0; and Expression (4): P A >0.2.

  一种生产纤维素衍生物薄膜的方法，该方法包括：使用包括满足以下条件（a）和（b）的纤维素衍生物的溶胶，通过溶剂浇铸法形成薄膜：（a）纤维素的葡萄糖单元中的三个羟基中的至少一个被取代为极化率各向异性Δα（以下表达式（1）表示）为2.5×10-24cm3或更高的取代基：表达式（1）：Δα=αx-（αy+αz）/ 2，其中αx，αy和αz如规范中定义的；并且（b）当Δα为2.5×10-24cm3或更高的取代基的取代度为PA时，Δα低于2.5×10-24cm3的取代基的取代度为PB，PA和PB满足以下表达式（3）和（4）：表达式（3）：2PA + PB> 3.0；表达式（4）：PA> 0.2。
• Access to <i>N</i>-Alkylazaheterocyclic Salts by Activation of Alkoxy C–O Bonds in Polyol Esters
  作者：Zhan Shi、Qiang Bian、Zhi Li

  DOI：10.1021/acs.joc.3c00383

  日期：2023.7.21

  are conveniently synthesized from polyol esters and azaheterocyclic salts under solventless conditions. In particular, paraquat-like derivatives showed comparable herbicidal activity toward several common weeds. Mechanistic studies suggest that polyesters likely underwent partial hydrolysis and neighboring group participating dehydration under the action of acidic salt to generate five-membered ring

  在无溶剂条件下，可以由多元醇酯和氮杂杂环盐方便地合成多种N-烷基氮杂杂环盐。特别是，百草枯样衍生物对几种常见杂草表现出相当的除草活性。机理研究表明，聚酯可能在酸性盐的作用下发生部分水解和邻基参与脱水，生成五元环中间体，与氮杂环反应完成N-烷基化。