1-(2,3-Dichlorophenyl)pentan-1-ol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(2,3-Dichlorophenyl)pentan-1-ol
• 化学式: C₁₁H₁₄Cl₂O
• 分子量: 233.138
• InChiKey: UUPZDIJADKQRMX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-(2,3-Dichlorophenyl)pentan-1-ol 在 phosphorus pentoxide 作用下， 以 Petroleum ether 为溶剂， 生成 1,2-Dichloro-3-((Z)-pent-1-enyl)-benzene
  参考文献：
  名称：

  The Synthesis and Transition Temperatures of Some Ortho-Dichloroterphenyls for Ferroelectric Mixtures

  摘要：

  A range of ortho-dichloroterphenyls has been prepared and evaluated for their transition temperatures and physical properties. The analogous ortho difluoro-substituted materials have been very successful as ferroelectric host materials. It was expected that the dichloro-substituted compounds would provide a greater lateral dipole and confer of dielectric biaxiality. State of the art synthetic techniques were used. For example, low-temperature ortho directed metallations provided arylboronic acids which were used in palladium-catalysed cross-coupling reactions to provide final materials. Materials with low melting points that exhibit the S-C phase have been produced.

  DOI：

  10.1080/10587259508038694
• 作为产物：
  描述：

  正戊醛 、 邻二氯苯 在 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 以76%的产率得到1-(2,3-Dichlorophenyl)pentan-1-ol
  参考文献：
  名称：

  The Synthesis and Transition Temperatures of Some Ortho-Dichloroterphenyls for Ferroelectric Mixtures

  摘要：

  A range of ortho-dichloroterphenyls has been prepared and evaluated for their transition temperatures and physical properties. The analogous ortho difluoro-substituted materials have been very successful as ferroelectric host materials. It was expected that the dichloro-substituted compounds would provide a greater lateral dipole and confer of dielectric biaxiality. State of the art synthetic techniques were used. For example, low-temperature ortho directed metallations provided arylboronic acids which were used in palladium-catalysed cross-coupling reactions to provide final materials. Materials with low melting points that exhibit the S-C phase have been produced.

  DOI：

  10.1080/10587259508038694

文献信息

• The Synthesis and Transition Temperatures of Some <i>Ortho</i>-Dichloroterphenyls for Ferroelectric Mixtures
  作者：Michael Hird、Kenneth J. Toyne、Paul Hindmarsh、J. Clifford Jones、Victoria Minter

  DOI：10.1080/10587259508038694

  日期：1995.2

  A range of ortho-dichloroterphenyls has been prepared and evaluated for their transition temperatures and physical properties. The analogous ortho difluoro-substituted materials have been very successful as ferroelectric host materials. It was expected that the dichloro-substituted compounds would provide a greater lateral dipole and confer of dielectric biaxiality. State of the art synthetic techniques were used. For example, low-temperature ortho directed metallations provided arylboronic acids which were used in palladium-catalysed cross-coupling reactions to provide final materials. Materials with low melting points that exhibit the S-C phase have been produced.