5-(9H-carbazol-9-yl)pentanoic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 5-(9H-carbazol-9-yl)pentanoic acid
• 英文别名: 5-Carbazol-9-yl-pentanoic acid；5-carbazol-9-ylpentanoic acid
• 化学式: C₁₇H₁₇NO₂
• 分子量: 267.327
• InChiKey: YEPJVQJMLQBLOE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  42.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5-(9H-carbazol-9-yl)pentanoic acid 在 草酰氯 作用下， 以 苯 为溶剂， 反应 6.0h， 以80%的产率得到5-(9H-carbazol-9-yl)pentanoyl chloride
  参考文献：
  名称：

  Influence of polyhedral oligomeric silsesquioxanes (POSS) on blue light-emitting materials for OLED

  摘要：

  By using Heck polycondensation, we have synthesized carbazole-based alt-copolymers tethered with polyhedral oligomeric silsesquioxanes (POSS), which had well-defined architectures, similar polymerization degrees and the different contents of POSS. The effect of POSS content and the length of the side chain containing FOSS on the electroluminescence properties of these polymers were investigated. POSS particles in these alt-copolymers showed excellent dispersity and prevented the interchain aggregation of polymers in film state well. Besides, POSS benefited charge balance by increasing the electron current density, which led to a higher luminance and current efficiency, as well as purer blue light-emitting. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.11.082
• 作为产物：
  描述：

  5-carbazol-9-yl-pentanoic acid ethyl ester 在 potassium hydroxide 作用下， 以 乙醇 为溶剂， 反应 24.0h， 以84%的产率得到5-(9H-carbazol-9-yl)pentanoic acid
  参考文献：
  名称：

  具有光学和电子特性的功能咔唑液晶嵌段共混物

  摘要：

  据报道，由高度通用的介晶和含咔唑的2,2-双（羟甲基）丙酸（bis-MPA）树突组成的嵌段共修饰分子家族的合成与表征。通过差示扫描量热法，偏光光学显微镜和X射线衍射研究了液晶行为。根据组成树突的化学结构，共生分子显示出层状或柱状中间相。根据实验结果，提出了分子水平和中间相的模型。研究了咔唑部分在其结构中的存在所产生的嵌段共聚体的物理性质：溶液和中间相中的光致发光，电化学行为和空穴传输。

  DOI：

  10.1002/chem.201404555

文献信息

• Electropolymerization of Metal Clusters Establishing a Versatile Platform for Enhanced Catalysis Performance
  作者：Yi‐Man Wang、Jinmeng Cai、Qian‐You Wang、Yao Li、Zhen Han、Si Li、Chun‐Hua Gong、Shan Wang、Shuang‐Quan Zang、Thomas C. W. Mak

  DOI：10.1002/anie.202114538

  日期：2022.3

  A series of metal-cluster hybrid materials was successfully fabricated by using the electropolymerization (EP) method. Poly-metal clusters in an extended conjugated network establish an electron transport highway to catalytic sites. The improvement in catalytic performance in poly-metal clusters was demonstrated by electrocatalytic reduction of nitrate (NO3−) to ammonia (NH3) and photocatalytic chemical

  采用电聚合（EP）方法成功制备了一系列金属簇杂化材料。扩展共轭网络中的多金属簇建立了通往催化位点的电子传输高速公路。通过将硝酸盐 (NO 3 - )电催化还原为氨 (NH 3 ) 和光催化化学战模拟物降解实验证明了多金属簇中催化性能的改进。
• [EN] HDAC INHIBITORS AND THERAPEUTIC METHODS USING THE SAME<br/>[FR] INHIBITEURS DE HDAC ET PROCÉDÉS THÉRAPEUTIQUES LES UTILISANT
  申请人：UNIV ILLINOIS

  公开号：WO2011011186A2

  公开（公告）日：2011-01-27

  Histone deacetylases inhibitors (HDACIs) and compositions containing the same are disclosed. Methods of treating diseases and conditions wherein inhibition of HDAC provides a benefit, like a cancer, a neurodegenerative disorder, a neurological disease, traumatic brain injury, stroke, malaria, an autoimmune disease, autism, and inflammation, also are disclosed.
• Functional Carbazole Liquid-Crystal Block Codendrimers with Optical and Electronic Properties
  作者：Ismael Gracia、Beatriz Feringán、José Luis Serrano、Roberto Termine、Attilio Golemme、Ana Omenat、Joaquín Barberá

  DOI：10.1002/chem.201404555

  日期：2015.1.12

  family of block codendrimers consisting of highly versatile mesogenic and carbazole‐containing 2,2‐bis(hydroxymethyl)propionic acid (bis‐MPA) dendrons are reported. The liquid‐crystal behaviour was investigated by means of differential scanning calorimetry, polarised‐light optical microscopy and X‐ray diffraction. Depending on the chemical structure of the constituent dendrons, the codendrimers show lamellar

  据报道，由高度通用的介晶和含咔唑的2,2-双（羟甲基）丙酸（bis-MPA）树突组成的嵌段共修饰分子家族的合成与表征。通过差示扫描量热法，偏光光学显微镜和X射线衍射研究了液晶行为。根据组成树突的化学结构，共生分子显示出层状或柱状中间相。根据实验结果，提出了分子水平和中间相的模型。研究了咔唑部分在其结构中的存在所产生的嵌段共聚体的物理性质：溶液和中间相中的光致发光，电化学行为和空穴传输。
• Influence of polyhedral oligomeric silsesquioxanes (POSS) on blue light-emitting materials for OLED
  作者：Tianfu Zhang、Jinze Wang、Manxi Zhou、Li Ma、Guangzhong Yin、Guangxin Chen、Qifang Li

  DOI：10.1016/j.tet.2013.11.082

  日期：2014.4

  By using Heck polycondensation, we have synthesized carbazole-based alt-copolymers tethered with polyhedral oligomeric silsesquioxanes (POSS), which had well-defined architectures, similar polymerization degrees and the different contents of POSS. The effect of POSS content and the length of the side chain containing FOSS on the electroluminescence properties of these polymers were investigated. POSS particles in these alt-copolymers showed excellent dispersity and prevented the interchain aggregation of polymers in film state well. Besides, POSS benefited charge balance by increasing the electron current density, which led to a higher luminance and current efficiency, as well as purer blue light-emitting. (C) 2014 Elsevier Ltd. All rights reserved.