10-hydroxystrictosidine

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 10-hydroxystrictosidine
• 化学式: C₂₇H₃₄N₂O₁₀
• 分子量: 546.574
• InChiKey: QLABDTXGSORRAP-UOLVONRJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  39.0
• 可旋转键数：
  7.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  182.96
• 氢给体数：
  7.0
• 氢受体数：
  11.0

反应信息

• 作为产物：
  描述：

  5-羟基色胺 、 开联番木鳖苷 在 recombinant strictosidine synthase 作用下， 以 phosphate buffer 为溶剂， 生成 10-hydroxystrictosidine
  参考文献：
  名称：

  Substrate specificity of strictosidine synthase

  摘要：

  Strictosidine synthase catalyzes a Pictet-Spengler reaction in the first step in the biosynthesis of terpene indole alkaloids to generate strictosidine. The substrate requirements for strictosidine synthase are systematically and quantitatively examined and the enzymatically generated compounds are processed by the second enzyme in this biosynthetic pathway. (C) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2006.01.098

文献信息

• Substrate specificity of strictosidine synthase
  作者：Elizabeth McCoy、M. Carmen Galan、Sarah E. O’Connor

  DOI：10.1016/j.bmcl.2006.01.098

  日期：2006.5

  Strictosidine synthase catalyzes a Pictet-Spengler reaction in the first step in the biosynthesis of terpene indole alkaloids to generate strictosidine. The substrate requirements for strictosidine synthase are systematically and quantitatively examined and the enzymatically generated compounds are processed by the second enzyme in this biosynthetic pathway. (C) 2006 Elsevier Ltd. All rights reserved.