乙烯二(羟基乙酸酯) | 52767-61-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 乙烯二(羟基乙酸酯)
• 中文别名: 2,6-二氟-3-甲氧苄基胺
• 英文名称: 1,2-ethandiyl bis(2-hydroxyacetate)
• 英文别名: HGEgG'H；1,2-bis-glycoloyloxy-ethane；Aethylenglykol-bis-hydroxyacetat；1,2-Bis-glykoloyloxy-aethan；Ethylene bis(hydroxyacetate)；ethylene glycol diglycolate；2-(2-hydroxyacetyl)oxyethyl 2-hydroxyacetate
• CAS: 52767-61-0
• 化学式: C₆H₁₀O₆
• 分子量: 178.142
• InChiKey: KCZIRQGMWBGPRP-UHFFFAOYSA-N

物化性质

• 沸点：
  133 °C(Press: 10 Torr)
• 密度：
  1.327 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  -1.3
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  93.1
• 氢给体数：
  2
• 氢受体数：
  6

安全信息

• 海关编码：
  2918199090

反应信息

• 作为反应物：
  描述：

  4-tert-butyl-N-[6-chloro-5-(3-methoxy-phenoxy)-2-(thiophen-2-yl)-pyrimidin-4-yl]-benzenesulfonamide 、 乙烯二(羟基乙酸酯) 以 乙二醇 为溶剂， 生成 4-tert-butyl-N-[6-(2-hydroxy-ethoxy)-5-(3-methoxy-phenoxy)-2-(thiophen-2-yl)-pyrimidin-4-yl]-benzenesulfonamide
  参考文献：
  名称：

  Sulfonamides

  摘要：

  化学式I的新磺胺类化合物，##STR1## 其中符号R.sup.1 -R.sup.9，R.sup.a，R.sup.b，X，Y和n的含义如描述中所示，以及其盐可用于治疗循环系统疾病，特别是高血压、缺血、血管痉挛和心绞痛。

  公开号：

  US05292740A1
• 作为产物：
  描述：

  羟乙酸甲酯 、 乙二醇 在 甲醇 、 potassium carbonate 作用下， 生成 乙烯二(羟基乙酸酯)
  参考文献：
  名称：

  Esters of substituted acetic acids

  摘要：

  公开号：

  US02350360A1

文献信息

• OXYGEN SCAVENGING MOLECULES, ARTICLES CONTAINING SAME, AND METHODS OF THEIR USE
  申请人：Deshpande Girish Nilkanth

  公开号：US20110251395A1

  公开（公告）日：2011-10-13

  The invention relates to compounds of the structure of formula I and II: where X is selected from the group consisting of O, S and NH; Y, A and B are independently selected from the group consisting of N and CH; D, E and F are independently selected from the group consisting of CH, N, O and S; the symbol represents a single or a double bond; and R 1 , R 2 and R 3 are independently selected from the group consisting of H, electron withdrawing groups and electron releasing groups. In other embodiments, the compounds are used as oxygen scavengers and in barrier compositions and articles.

  该发明涉及结构为公式I和II的化合物：其中X从O、S和NH组成的群体中选择；Y、A和B从N和CH组成的群体中独立选择；D、E和F从CH、N、O和S组成的群体中独立选择；符号代表单键或双键；R1、R2和R3从H、电子吸引基团和电子释放基团组成的群体中独立选择。在其他实施方式中，这些化合物被用作氧清除剂，以及在屏障组合物和制品中使用。
• ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS
  申请人：The Regents of the University of California

  公开号：US20140371444A1

  公开（公告）日：2014-12-18

  Embodiments of the present disclosure provide for methods of making an organoboron compound, organoboron compounds, and the like.

  本公开的实施例提供了制备有机硼化合物、有机硼化合物等方法。
• HYDROCARBOXYLATION OF FORMALDEHYDE IN THE PRESENCE OF A HIGHER ORDER CARBOXYLIC ACID AND HETEROGENEOUS CATALYST
  申请人：Barnicki Scott Donald

  公开号：US20130261333A1

  公开（公告）日：2013-10-03

  Disclosed is a process for the production and purification of glycolic acid or glycolic acid derivatives by the carbonylation of formaldehyde in the presence of a solid acid catalyst and a carboxylic acid. This invention discloses hydrocarboxylations and corresponding glycolic acid separations wherein the glycolic acid stream is readily removed from the carboxylic acid and the carboxylic acid is recycled.

  本发明揭示了一种通过在固体酸催化剂和羧酸存在下对甲醛进行羰基化生产和纯化乙醇酸或乙醇酸衍生物的方法。本发明揭示了水合羧化反应和相应的乙醇酸分离，其中乙醇酸流可轻松从羧酸中分离出来，而羧酸则可循环利用。
• HYDROCARBOXYLATION OF FORMALDEHYDE IN THE PRESENCE OF A HIGHER ORDER CARBOXYLIC ACID AND A HOMOGENEOUS CATALYST
  申请人：Barnicki Scott Donald

  公开号：US20130261328A1

  公开（公告）日：2013-10-03

  Disclosed is a process for the production and purification of glycolic acid or glycolic acid derivatives by the carbonylation of formaldehyde in the presence of a homogeneous acid catalyst and a carboxylic acid. This invention discloses hydrocarboxylations and corresponding homogeneous acid catalyst and glycolic acid separations. The homogeneous acid catalyst is readily separated from the hydrocarboxylation reaction effluent and recycled and the carboxylic acid is readily removed from the glycolic acid and the carboxylic acid is recycled.

  本发明揭示了一种通过在均相酸催化剂和羧酸的存在下对甲醛进行羰基化生产和纯化乙醇酸或乙醇酸衍生物的方法。该发明揭示了烃羧化和相应的均相酸催化剂和乙醇酸分离。均相酸催化剂可容易地从烃羧化反应产物中分离并回收，羧酸可容易地从乙醇酸中去除并回收。
• HYDROCARBOXYLATION OF METHYLENE DIPROPIONATE IN THE PRESENCE OF PROPIONIC ACID AND A HETEROGENEOUS CATALYST
  申请人：Barnicki Scott Donald

  公开号：US20130261337A1

  公开（公告）日：2013-10-03

  Disclosed is a process for the production and purification of glycolic acid or glycolic acid derivatives by the carbonylation of methylene dipropionate in the presence of a solid acid catalyst and propionic acid. This invention discloses hydrocarboxylations and corresponding glycolic acid separations wherein the propionic acid stream is readily removed from the glycolic acid and the propionic acid is recycled.

  本发明揭示了一种通过在固体酸催化剂和丙酸存在下将亚甲基二丙酸酯羰化来生产和纯化甘醇酸或甘醇酸衍生物的方法。本发明揭示了烃羧化和相应的甘醇酸分离，其中丙酸流容易从甘醇酸中去除，丙酸可循环利用。