(3-hydroxybutan-2-yl) (2S)-2-hydroxypropanoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (3-hydroxybutan-2-yl) (2S)-2-hydroxypropanoate
• 英文别名: 2(S)-3'-hydroxybutan-2'-yl 2-hydroxypropanoate；3-hydroxybutan-2-yl (2S)-2-hydroxypropanoate
• 化学式: C₇H₁₄O₄
• 分子量: 162.186
• InChiKey: IYGRJVIQVSHNEI-XRVVJQKQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (3-hydroxybutan-2-yl) (2S)-2-hydroxypropanoate 在 potassium hydroxide 作用下， 以 1,4-二氧六环 为溶剂， 反应 5.0h， 生成 L-乳酸
  参考文献：
  名称：

  Two new compounds from the metabolites of a marine-derived actinomyceteStreptomyces cavourensisYY01-17

  摘要：

  Our current marine natural product program investigated the second metabolites of an actinomycete Streptomyces cavourensis YY01-17 originating from the Antarctic ecological niche to discover potential antitumor chemical entities. Two new compounds, along with a known compound, were isolated from the ethyl acetate extract of the fermentation broth of the marine-derived actinomycete, and their structures were elucidated, respectively, as 2(S)-3-hydroxybutan-2-yl 2-hydroxypropanoate (1), (E)-3-hydroxy-2,4-dimethylhept-4-enamide (2), and 2-hydroxy-3-methylbutanoic acid (3) on the basis of spectroscopic data interpretation.

  DOI：

  10.1080/10286020.2012.762764

文献信息

• Two new compounds from the metabolites of a marine-derived actinomycete<i>Streptomyces cavourensis</i>YY01-17
  作者：Shan-Shan Su、Li Tian、Gang Chen、Zhan-Qiang Li、Wen-Feng Xu、Yue-Hu Pei

  DOI：10.1080/10286020.2012.762764

  日期：2013.3

  Our current marine natural product program investigated the second metabolites of an actinomycete Streptomyces cavourensis YY01-17 originating from the Antarctic ecological niche to discover potential antitumor chemical entities. Two new compounds, along with a known compound, were isolated from the ethyl acetate extract of the fermentation broth of the marine-derived actinomycete, and their structures were elucidated, respectively, as 2(S)-3-hydroxybutan-2-yl 2-hydroxypropanoate (1), (E)-3-hydroxy-2,4-dimethylhept-4-enamide (2), and 2-hydroxy-3-methylbutanoic acid (3) on the basis of spectroscopic data interpretation.