stearyl-α-D-galactopyranoside

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: stearyl-α-D-galactopyranoside
• 英文别名: (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-(octadecyloxy)tetrahydro-2H-pyran-3,4,5-triol；(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-octadecoxyoxane-3,4,5-triol
• 化学式: C₂₄H₄₈O₆
• 分子量: 432.642
• InChiKey: UFSKIYBOKFBSOA-BAHGYDIPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  30
• 可旋转键数：
  19
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  99.4
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  硬脂醇 在 甲醇 、 sodium methylate 、 四氯化锡 作用下， 以 二氯甲烷 为溶剂， 反应 48.0h， 生成 stearyl-α-D-galactopyranoside
  参考文献：
  名称：

  Thermotropic and lyotropic properties of long chain alkyl glycopyranosides

  摘要：

  A systematic structure variation of a classical amphiphile (dodecyl-P-D-glucopyranoside) is performed, demonstrating the influence of anomeric linkage, configuration, ring size and flexibility as well as electric charges on the mesophase behaviour. In addition, we have investigated the thermotropic and lyotropic properties of some long chain alkyl glycosides with monosaccharide headgroups. The thermotropism was measured with polarizing microscopy and differential scanning calorimetry, and additionally the lyotropism with FTIR spectroscopy and X-ray diffraction. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

  DOI：

  10.1016/s0009-3084(99)00119-x

文献信息

• Synthesis and characterization of mesogenic alkyl O-glycosides and their drug release studies
  作者：Saliha Nazir、Hina Daud、Erum Akbar Hussain

  DOI：10.1016/j.molliq.2022.121138

  日期：2023.2
• Thermotropic and lyotropic properties of long chain alkyl glycopyranosides
  作者：V. Vill、H.M. von Minden、M.H.J. Koch、U. Seydel、K. Brandenburg

  DOI：10.1016/s0009-3084(99)00119-x

  日期：2000.1

  A systematic structure variation of a classical amphiphile (dodecyl-P-D-glucopyranoside) is performed, demonstrating the influence of anomeric linkage, configuration, ring size and flexibility as well as electric charges on the mesophase behaviour. In addition, we have investigated the thermotropic and lyotropic properties of some long chain alkyl glycosides with monosaccharide headgroups. The thermotropism was measured with polarizing microscopy and differential scanning calorimetry, and additionally the lyotropism with FTIR spectroscopy and X-ray diffraction. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.