gen-β-OC18

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: gen-β-OC18
• 英文别名: (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-octadecoxyoxan-2-yl]methoxy]oxane-3,4,5-triol
• 化学式: C₃₀H₅₈O₁₁
• 分子量: 594.784
• InChiKey: BXRHQSSZAKYXMB-OTJWROPPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  41
• 可旋转键数：
  22
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  179
• 氢给体数：
  7
• 氢受体数：
  11

反应信息

• 作为产物：
  描述：

  硬脂醇 在 甲醇 、 三氟化硼乙醚 、 sodium methylate 作用下， 以 二氯甲烷 为溶剂， 反应 4.0h， 生成 gen-β-OC18
  参考文献：
  名称：

  Thermotropic and lyotropic properties of long chain alkyl glycopyranosides. Part II. Disaccharide headgroups

  摘要：

  We have investigated the thermotropic and lyotropic properties of some long chain alkyl glycosides with disaccharide headgroups. The thermotropism was measured with polarising microscopy and additionally the lyotropism with the contact preparation method, Fourier-transform Infrared (FTIR) spectroscopy, X-ray diffraction and small angle neutron scattering. A broad thermotropic as well as lyotropic polymorphism was found. The compounds displayed thermotropic S-A (lamellar) and cubic phases, and the investigation of the lyotropic phase behaviour led to the observation of inverted bicontinuous cubic V-II phases, lamellar L-alpha phases, normal bicontinuous cubic V-I phases, normal columnar H-I phases, normal discontinuous cubic I-I f phases and lyotropic cholesteric phases. The phases are discussed with respect to the chemical structures that have been varied systematically to derive structure-property relationships. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

  DOI：

  10.1016/s0009-3084(00)00151-1

文献信息

• Thermotropic and lyotropic properties of long chain alkyl glycopyranosides. Part II. Disaccharide headgroups
  作者：H.M von Minden、K Brandenburg、U Seydel、M.H.J Koch、V Garamus、R Willumeit、V Vill

  DOI：10.1016/s0009-3084(00)00151-1

  日期：2000.8

  We have investigated the thermotropic and lyotropic properties of some long chain alkyl glycosides with disaccharide headgroups. The thermotropism was measured with polarising microscopy and additionally the lyotropism with the contact preparation method, Fourier-transform Infrared (FTIR) spectroscopy, X-ray diffraction and small angle neutron scattering. A broad thermotropic as well as lyotropic polymorphism was found. The compounds displayed thermotropic S-A (lamellar) and cubic phases, and the investigation of the lyotropic phase behaviour led to the observation of inverted bicontinuous cubic V-II phases, lamellar L-alpha phases, normal bicontinuous cubic V-I phases, normal columnar H-I phases, normal discontinuous cubic I-I f phases and lyotropic cholesteric phases. The phases are discussed with respect to the chemical structures that have been varied systematically to derive structure-property relationships. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.