3-O-{β-D-xylopyranosyl-(1->3)-[β-D-xylopyranosyl(1->2)]-β-D-glucopyranosyl(1->4)-[α-L-rhamnopyranosyl(1->2)]-β-D-galactopyranosy}-26-O-β-D-glucopyranosyl-5a-furostan-12-one-(25R)-22-methoxy-3β,26-diol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3-O-{β-D-xylopyranosyl-(1->3)-[β-D-xylopyranosyl(1->2)]-β-D-glucopyranosyl(1->4)-[α-L-rhamnopyranosyl(1->2)]-β-D-galactopyranosy}-26-O-β-D-glucopyranosyl-5a-furostan-12-one-(25R)-22-methoxy-3β,26-diol
• 英文别名: terrestroside B
• 化学式: C₆₂H₁₀₂O₃₂
• 分子量: 1359.47
• InChiKey: LOXXUPHBHNNNKD-GRACJHEVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -6.17
• 重原子数：
  94.0
• 可旋转键数：
  20.0
• 环数：
  11.0
• sp3杂化的碳原子比例：
  0.98
• 拓扑面积：
  490.2
• 氢给体数：
  17.0
• 氢受体数：
  32.0

反应信息

• 作为反应物：
  描述：

  3-O-{β-D-xylopyranosyl-(1->3)-[β-D-xylopyranosyl(1->2)]-β-D-glucopyranosyl(1->4)-[α-L-rhamnopyranosyl(1->2)]-β-D-galactopyranosy}-26-O-β-D-glucopyranosyl-5a-furostan-12-one-(25R)-22-methoxy-3β,26-diol 在 盐酸 、 水 、 吡啶 、 盐酸羟胺 作用下， 反应 3.0h， 生成 D-glucose oxime 、 galactose oxime 、 、 D-木糖肟
  参考文献：
  名称：

  Five furostanol saponins from fruits of Tribulus terrestris and their cytotoxic activities

  摘要：

  Two new furostanol saponins, terrestroside A, 3-O-{-D-xylopyranosyl-(1 3)-[-D-xylopyranosyl(1 2)]--D-glucopyranosyl(1 4)-[-L-rhamnopyranosyl(1 2)]--D-galactopyranosy}-26-O--D-glucopyranosyl-L-5a-furost-20(22)-en-(25R)-3,26-diol (1) and terrestroside B, 3-O-{-D-xylopyran-osyl(1 3)-[-D-xylopyranosyl(1 2)]--D-glucopyranosyl(1 4)-[-L-rhamnopyranosyl-(1 2)]--D-galactopyranosy}-26-O--D-glucopyranosyl-5a-furostan-12-one-(25R)-22-methoxy-3,26-diol (2), together with three known compounds, chloromaloside E (3), terrestrinin B (4) and terrestroneoside A (5) were isolated from the dry fruits of Tribulus terrestris. Furthermore, the inhibitory effects of the compounds on tumour cells were evaluated, and compounds 1-5 showed potential anti-tumour activity.

  DOI：

  10.1080/14786410902940990

文献信息

• Five furostanol saponins from fruits of <i>Tribulus terrestris</i> and their cytotoxic activities
  作者：Jue Wang、Xuyu Zu、Yuyang Jiang

  DOI：10.1080/14786410902940990

  日期：2009.10.15

  Two new furostanol saponins, terrestroside A, 3-O--D-xylopyranosyl-(1 3)-[-D-xylopyranosyl(1 2)]--D-glucopyranosyl(1 4)-[-L-rhamnopyranosyl(1 2)]--D-galactopyranosy}-26-O--D-glucopyranosyl-L-5a-furost-20(22)-en-(25R)-3,26-diol (1) and terrestroside B, 3-O--D-xylopyran-osyl(1 3)-[-D-xylopyranosyl(1 2)]--D-glucopyranosyl(1 4)-[-L-rhamnopyranosyl-(1 2)]--D-galactopyranosy}-26-O--D-glucopyranosyl-5a-furostan-12-one-(25R)-22-methoxy-3,26-diol (2), together with three known compounds, chloromaloside E (3), terrestrinin B (4) and terrestroneoside A (5) were isolated from the dry fruits of Tribulus terrestris. Furthermore, the inhibitory effects of the compounds on tumour cells were evaluated, and compounds 1-5 showed potential anti-tumour activity.