N-ethylformamide hydrochloride

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-ethylformamide hydrochloride
• 英文别名: ethylformamide hydrochloride；N-ethylformamide;hydrochloride
• 化学式: C₃H₇NO*ClH
• 分子量: 109.556
• InChiKey: OKVSEPXFKOQRQV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.17
• 重原子数：
  6
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  29.1
• 氢给体数：
  2
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  磺酰罗丹明B 在 盐酸 、 氧气 、 dioxide titanium 作用下， 以 水 为溶剂， 反应 17.0h， 生成 乙醛 、 二乙胺 、 N-ethylformamide hydrochloride 、 N,N-diethylformamide hydrochloride
  参考文献：
  名称：

  Photooxidation Pathway of Sulforhodamine-B. Dependence on the Adsorption Mode on TiO₂ Exposed to Visible Light Radiation

  摘要：

  The temporal course of the photooxidation of sulforhodamine-B (SRB) in aqueous media illuminated by visible wavelengths in the presence of TiO2 has been examined to determine the nature of the intermediate species produced and to explore the operative reaction pathway(s). Two pathways are described to account for the differences in the final photooxidation products whose nature depends on the different modes of adsorption of the dye on the metaloxide mediator. In the SRB/TiO2 system, when SRB is adsorbed on the positively charged TiO2 particle surface through a sulfonate group cleavage of the SRB chromophore structure predominates and N-de-ethylation occurs only to a slight extent with the major photooxidation products being diethylamine and carbon dioxide. in the presence of the anionic dodecylbenzenesulfonate surfactant DBS, when SRB is near the negatively charged DBS/TiO2 interface through the positive diethylamine group N-de-ethylation occurs preferentially before destruction of the structure with the major products being acetaldehyde and carbon dioxide.

  DOI：

  10.1021/es001064c
• 作为试剂：
  描述：

  2-bromo-1-methoxy-hexan-3-one 在 N-ethylformamide hydrochloride 作用下， 以 氨 为溶剂， 生成 2-ethyl-4-methoxy-butyric acid amide
  参考文献：
  名称：

  杂环核磁共振波谱，第 6 版。液氨中咪唑环化反应中 α-溴-β-甲氧基-酮的 Favorskii 重排

  摘要：

  在液氨中由 α-溴酮和甲亚氨基乙酯合成咪唑时，副产物 α-烷基取代的丁酰胺得到，其形成归因于 Favorskii 重排。通过NMR光谱检查分离的化合物。

  DOI：

  10.1002/ardp.19793120206

文献信息

• Photooxidation Pathway of Sulforhodamine-B. Dependence on the Adsorption Mode on TiO₂ Exposed to Visible Light Radiation
  作者：Guangming Liu、Xiangzhong Li、Jincai Zhao、Hisao Hidaka、Nick Serpone

  DOI：10.1021/es001064c

  日期：2000.9.1

  The temporal course of the photooxidation of sulforhodamine-B (SRB) in aqueous media illuminated by visible wavelengths in the presence of TiO2 has been examined to determine the nature of the intermediate species produced and to explore the operative reaction pathway(s). Two pathways are described to account for the differences in the final photooxidation products whose nature depends on the different modes of adsorption of the dye on the metaloxide mediator. In the SRB/TiO2 system, when SRB is adsorbed on the positively charged TiO2 particle surface through a sulfonate group cleavage of the SRB chromophore structure predominates and N-de-ethylation occurs only to a slight extent with the major photooxidation products being diethylamine and carbon dioxide. in the presence of the anionic dodecylbenzenesulfonate surfactant DBS, when SRB is near the negatively charged DBS/TiO2 interface through the positive diethylamine group N-de-ethylation occurs preferentially before destruction of the structure with the major products being acetaldehyde and carbon dioxide.